25,703 research outputs found
Recent Developments in Fermion Simulation Algorithms
A summary of recent developments in the field of simulation algorithms for
dynamical fermions is given.Comment: Plenary talk given at the International Symposium on Lattice Field
Theory, 4-8 June 1996, St. Louis, Mo, USA, Latex, 3 Figures, 7 page
Recent developments in the tmLQCD software suite
We present an overview of recent developments in the tmLQCD software suite.
We summarise the features of the code, including actions and operators
implemented. In particular, we discuss the optimisation efforts for modern
architectures using the Blue Gene/Q system as an example.Comment: presented at the 31st International Symposium on Lattice Field Theory
(Lattice 2013), 29 July - 3 August 2013, Mainz, German
Status and Future Perspectives for Lattice Gauge Theory Calculations to the Exascale and Beyond
In this and a set of companion whitepapers, the USQCD Collaboration lays out
a program of science and computing for lattice gauge theory. These whitepapers
describe how calculation using lattice QCD (and other gauge theories) can aid
the interpretation of ongoing and upcoming experiments in particle and nuclear
physics, as well as inspire new ones.Comment: 44 pages. 1 of USQCD whitepapers
The Rational Hybrid Monte Carlo Algorithm
The past few years have seen considerable progress in algorithmic development
for the generation of gauge fields including the effects of dynamical fermions.
The Rational Hybrid Monte Carlo (RHMC) algorithm, where Hybrid Monte Carlo is
performed using a rational approximation in place the usual inverse quark
matrix kernel is one of these developments. This algorithm has been found to be
extremely beneficial in many areas of lattice QCD (chiral fermions, finite
temperature, Wilson fermions etc.). We review the algorithm and some of these
benefits, and we compare against other recent algorithm developements. We
conclude with an update of the Berlin wall plot comparing costs of all popular
fermion formulations.Comment: 15 pages. Proceedings from Lattice 200
Computational identification and analysis of noncoding RNAs - Unearthing the buried treasures in the genome
The central dogma of molecular biology states that the genetic information flows from DNA to RNA to protein. This dogma has exerted a substantial influence on our understanding of the genetic activities in the cells. Under this influence, the prevailing assumption until the recent past was that genes are basically repositories for protein coding information, and proteins are responsible for most of the important biological functions in all cells. In the meanwhile, the importance of RNAs has remained rather obscure, and RNA was mainly viewed as a passive intermediary that bridges the gap between DNA and protein. Except for classic examples such as tRNAs (transfer RNAs) and rRNAs (ribosomal RNAs), functional noncoding RNAs were considered to be rare.
However, this view has experienced a dramatic change during the last decade, as systematic screening of various genomes identified myriads of noncoding RNAs (ncRNAs), which are RNA molecules that function without being translated into proteins [11], [40]. It has been realized that many ncRNAs play important roles in various biological processes. As RNAs can interact with other RNAs and DNAs in a sequence-specific manner, they are especially useful in tasks that require highly specific nucleotide recognition [11]. Good examples are the miRNAs (microRNAs) that regulate gene expression by targeting mRNAs (messenger RNAs) [4], [20], and the siRNAs (small interfering RNAs) that take part in the RNAi (RNA interference) pathways for gene silencing [29], [30]. Recent developments show that ncRNAs are extensively involved in many gene regulatory mechanisms [14], [17].
The roles of ncRNAs known to this day are truly diverse. These include transcription and translation control, chromosome replication, RNA processing and modification, and protein degradation and translocation [40], just to name a few. These days, it is even claimed that ncRNAs dominate the genomic output of the higher organisms such as mammals, and it is being suggested that the greater portion of their genome (which does not encode proteins) is dedicated to the control and regulation of cell development [27]. As more and more evidence piles up, greater attention is paid to ncRNAs, which have been neglected for a long time. Researchers began to realize that the vast majority of the genome that was regarded as “junk,” mainly because it was not well understood, may indeed hold the key for the best kept secrets in life, such as the mechanism of alternative splicing, the control of epigenetic variations and so forth [27]. The complete range and extent of the role of ncRNAs are not so obvious at this point, but it is certain that a comprehensive understanding of cellular processes is not possible without understanding the functions of ncRNAs [47]
Minimizing synchronizations in sparse iterative solvers for distributed supercomputers
Eliminating synchronizations is one of the important techniques related to minimizing communications for modern high performance computing. This paper discusses principles of reducing communications due to global synchronizations in sparse iterative solvers on distributed supercomputers. We demonstrates how to minimizing global synchronizations by rescheduling a typical Krylov subspace method. The benefit of minimizing synchronizations is shown in theoretical analysis and is verified by numerical experiments using up to 900 processors. The experiments also show the communication complexity for some structured sparse matrix vector multiplications and global communications in the underlying supercomputers are in the order P1/2.5 and P4/5 respectively, where P is the number of processors and the experiments were carried on a Dawning 5000A
Progress on lattice QCD algorithms
I review recent progress on algorithms for calculating quark propagators and
for simulating full QCD.Comment: 8 uuencoded PostScript pages, contribution to LAT95 (fig.1 simplified
to conserve space; available upon request
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