5,313 research outputs found

    Predicting Alder shrub expansion in Sub-Arctic Alaska using machine learning, satellite data, and environmental variables

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    The wider Fairbanks area, a sub-Arctic region of Alaska, USA, is home to a variety of alpine, oroarctic tundra that is being impacted by climate warming. This has resulted in an infilling and expansion of shrubs across the tundra and an elevational increase in the range limits of tall shrubs. Expansion of Alder (a key pioneer tall shrub) is thought to result from Arctic warming and shifts in its spread are likely to be a result of such warming. Alder can fix atmospheric nitrogen by virtue of a mutualistic association with soil bacteria, which subsequently becomes available to other shrubs, potentially relieving local soil nitrogen limitations and promoting a positive growth response to climate warming. This potential landscape-scale change requires information of change at a suitable scale. However, Alder and other tall shrubs have been hard to measure using existing remote sensing approaches alone. This is mainly due to issues surrounding data availability and suitable spatial resolution of imagery. Satellite remote sensing and environmental data are combined to create a map of Alder expansion across the wider Fairbanks area. A methodology is presented where ecological variables are integrated into prediction maps using a combination of regression and machine learning to estimate spatial extents. A baseline for a minimum number of high resolution training polygons is found to understand minimum required inputs. Field-based validation data were collected using a random sampling design across four different locations within the Yukon-Koyukuk area, Alaska. The combination of satellite data and environmental variables yields the best results for predicting Alder locations across the study area with a model accuracy of 0.99 and User’s accuracy of 43.66%. Orthomosaics as validation data are found to be very useful, enabling better quantification of smaller plant functional types for more accurate error matrix class assignment increasing overall model accuracy

    Optimization of Beyond 5G Network Slicing for Smart City Applications

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    Transitioning from the current fifth-generation (5G) wireless technology, the advent of beyond 5G (B5G) signifies a pivotal stride toward sixth generation (6G) communication technology. B5G, at its essence, harnesses end-to-end (E2E) network slicing (NS) technology, enabling the simultaneous accommodation of multiple logical networks with distinct performance requirements on a shared physical infrastructure. At the forefront of this implementation lies the critical process of network slice design, a phase central to the realization of efficient smart city networks. This thesis assumes a key role in the network slicing life cycle, emphasizing the analysis and formulation of optimal procedures for configuring, customizing, and allocating E2E network slices. The focus extends to catering to the unique demands of smart city applications, encompassing critical areas such as emergency response, smart buildings, and video surveillance. By addressing the intricacies of network slice design, the study navigates through the complexities of tailoring slices to meet specific application needs, thereby contributing to the seamless integration of diverse services within the smart city framework. Addressing the core challenge of NS, which involves the allocation of virtual networks on the physical topology with optimal resource allocation, the thesis introduces a dual integer linear programming (ILP) optimization problem. This problem is formulated to jointly minimize the embedding cost and latency. However, given the NP-hard nature of this ILP, finding an efficient alternative becomes a significant hurdle. In response, this thesis introduces a novel heuristic approach the matroid-based modified greedy breadth-first search (MGBFS) algorithm. This pioneering algorithm leverages matroid properties to navigate the process of virtual network embedding and resource allocation. By introducing this novel heuristic approach, the research aims to provide near-optimal solutions, overcoming the computational complexities associated with the dual integer linear programming problem. The proposed MGBFS algorithm not only addresses the connectivity, cost, and latency constraints but also outperforms the benchmark model delivering solutions remarkably close to optimal. This innovative approach represents a substantial advancement in the optimization of smart city applications, promising heightened connectivity, efficiency, and resource utilization within the evolving landscape of B5G-enabled communication technology

    Understanding local neuromuscular mechanisms that explain the efficacy of interventions for patellofemoral pain

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    Patellofemoral pain (PFP) is a common and persistent knee pain complaint among all age ranges, especially highly active people. Multiple approaches have been used to understand symptom persistence, including identifying a mechanism explaining intervention benefits (i.e. changes in specific deficits in groups that show symptoms’ improvement). Research has been conducted to identify the characteristics associated with PFP, but uncertainty regarding local neuromuscular characteristics remain evident. The thesis aimed to a) identify the local neuromuscular characteristics associated with PFP, b) develop an evidence informed laboratory protocol to detect those characteristics, c) establish protocol reliability and feasibility, and d) identify interventions that can target these neuromuscular characteristics. A systematic review with meta-analysis was completed to identify the neuromuscular characteristics of all muscles that cross the knee in people with PFP compared to uninjured groups. Ten deficits within three neuromuscular domains were found. Within the electromyography (EMG) domain, a delay in Vastus medialis (VM) relative to Vastus lateralis (VL) excitation onset, a high Biceps femoris (BF) mean excitation amplitude, and a lower Hoffman-reflex amplitude of VM were identified. Within the muscle performance domain, lower isometric, concentric, and eccentric extensors peak torque and total work, lower concentric flexors peak torque, and lower rate of torque development (RTD) to reach 30%, 60% and 90% of extensors peak torque were identified. Hamstring tightness was identified within muscle flexibility domain. The systematic review was published and the results used to inform testing protocol development. A second systematic review with meta-analysis was conducted to identify interventions that can target the local deficits associated with PFP. The results indicate that currently an intervention that effectively modifies EMG characteristics cannot be identified. Predominantly, exercise interventions have effects on strength and flexibility in PFP. Specifically, hip and knee targeted exercises are found to have a potential mechanism of benefit through both characteristics categories. A unique approach was introduced within the thesis to develop a deficit-detection protocol based on systematic review results. This approach provided a comprehensive analysis of the protocols from the studies that were included in the meta-analysis. A battery of tests was developed and included; a) VM-VL excitation onset timing in step-up task, b) BF mean excitation amplitude in single-leg triple-hop test, c) isometric, d) concentric and e) eccentric extensors peak torque, f) RTD to 30%, 60% and 90% of isometric peak torque, and hamstrings flexibility. Reliability testing of the deficit-detection protocol was conducted with both uninjured and participants with PFP over two phases. Phase one evaluated the original protocols adapted from the review. Phase two was performed on the EMG and RTD domains to explore the effects of signal processing parameters on reliability, such as; onset detection thresholds modification, unnormalised signals, and the addition of absolute RTD. For the PFP group: reliable results were demonstrated for concentric and eccentric extensors peak torque; RTD of the quadriceps at 25ms, 50ms and 90% of peak torque; and hamstrings flexibility. The uninjured group showed reliable results in: unnormalised BF mean excitation amplitude; all three peak torque tests; RTD to 30% of peak torque and at 150 and 175 milliseconds; and hamstrings flexibility. To establish participant recruitment rate and retention, in addition to the acceptability of the test protocol, a preliminary feasibility study of the deficit-detection protocol was conducted. A sample of 14 participants with PFP were recruited and tested at the Mile-end campus of QMUL before and after a six weeks period. Feasibility results indicate that 25.5% were willing to participate following an online screening process (n=17/55) and 82% met the eligibility criteria following face-to-face assessment (n=14/17). Recruitment rate was 0.5 participants per week and drop-out rate was 35.2% (n=11/17). The results indicate that the protocol did not meet all a-priori feasibility criteria, but the results can inform future research planning. The thesis has successfully identified local deficits associated with PFP, developed a test protocol that demonstrates reliability in evaluating these deficits and assessed the feasibility of the protocol in individuals with PFP. Interventions to cause change within these local deficits have been identified, with gap maps demonstrating where further research is required to better align the mechanisms of treatment effects with specific deficits associated with PFP

    Unravelling the complex reproductive tactics of male humpback whales : an integrative analysis of paternity, age, testosterone, and genetic diversity

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    How the underlying forces of sexual selection impact reproductive tactics including elaborate acoustic displays in cetaceans remains poorly understood. Here, I combined 26 years (1995-2020) of photo-identification, behavioural, (epi)genetic, and endocrine data from an endangered population of humpback whales (New Caledonia), to explore male reproductive success, age, physiology, and population dynamics over almost a third of the lifespan of a humpback whale. First, I conducted a paternity analysis on 177 known mother-offspring pairs and confirmed previous findings of low variation in reproductive success in male humpback whales. Second, epigenetic age estimates of 485 males revealed a left-skewed population age structure in the first half of the study period that became more balanced in the second half. Further, older males (> 23 years) more often engaged in certain reproductive tactics (singing and escorting) and were more successful in siring offspring once the population age structure stabilised, suggesting reproductive tactics and reproductive success in male humpback whales may be age-dependent. Third, using enzyme immunoassays on 457 blubber samples, I observed a seasonal decline in male testosterone in the population over the breeding season. Testosterone levels appeared highest during puberty, then decreased and levelled off at the onset of maturity, yet were highly variable at any point during the breeding season and across males of all ages. Lastly, I investigated the influence of genetic diversity at the major histocompatibility complex (MHC) class I and class IIa (DQB and DRB-a) on patterns of male reproductive success in humpback whales. Mating pairs shared fewer alleles than expected under random mating at MHC class I and IIa, thus, providing evidence of an MHC-mediated female mate choice in humpback whales. This thesis provides novel, critical insights into the evolutionary consequences of commercial whaling on the demography, patterns of reproduction and sexual selection of exploited populations of baleen whales."This work was supported by a University of St Andrews School of Biology Ph.D. Scholarship and the Louis M. Herman Research Scholarship 2022 to Franca Eichenberger. Sample collection and analyses from 2018-2020 were supported by grants to Ellen C. Garland (Royal Society University Research Fellowship (UF160081 & URF\R\221020), Royal Society Research Fellows Enhancement Award (RGF\EA\180213), Royal Society Research Grants for Research Fellows 2018 (RGF\R1\181014), National Geographic Grant (#NGS-50654R-18), Carnegie Trust Research Incentive Grant (RIG007772), British Ecological Society Small Research Grant (SR18/1288) and School of Biology Research Committee funding)."--Fundin

    Digitalization and Development

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    This book examines the diffusion of digitalization and Industry 4.0 technologies in Malaysia by focusing on the ecosystem critical for its expansion. The chapters examine the digital proliferation in major sectors of agriculture, manufacturing, e-commerce and services, as well as the intermediary organizations essential for the orderly performance of socioeconomic agents. The book incisively reviews policy instruments critical for the effective and orderly development of the embedding organizations, and the regulatory framework needed to quicken the appropriation of socioeconomic synergies from digitalization and Industry 4.0 technologies. It highlights the importance of collaboration between government, academic and industry partners, as well as makes key recommendations on how to encourage adoption of IR4.0 technologies in the short- and long-term. This book bridges the concepts and applications of digitalization and Industry 4.0 and will be a must-read for policy makers seeking to quicken the adoption of its technologies

    LIPIcs, Volume 251, ITCS 2023, Complete Volume

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    LIPIcs, Volume 251, ITCS 2023, Complete Volum

    Algebraic solutions of linear differential equations: an arithmetic approach

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    Given a linear differential equation with coefficients in Q(x)\mathbb{Q}(x), an important question is to know whether its full space of solutions consists of algebraic functions, or at least if one of its specific solutions is algebraic. After presenting motivating examples coming from various branches of mathematics, we advertise in an elementary way a beautiful local-global arithmetic approach to these questions, initiated by Grothendieck in the late sixties. This approach has deep ramifications and leads to the still unsolved Grothendieck-Katz pp-curvature conjecture.Comment: 47 page

    Non-perturbative renormalization group analysis of nonlinear spiking networks

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    The critical brain hypothesis posits that neural circuits may operate close to critical points of a phase transition, which has been argued to have functional benefits for neural computation. Theoretical and computational studies arguing for or against criticality in neural dynamics largely rely on establishing power laws or scaling functions of statistical quantities, while a proper understanding of critical phenomena requires a renormalization group (RG) analysis. However, neural activity is typically non-Gaussian, nonlinear, and non-local, rendering models that capture all of these features difficult to study using standard statistical physics techniques. Here, we overcome these issues by adapting the non-perturbative renormalization group (NPRG) to work on (symmetric) network models of stochastic spiking neurons. By deriving a pair of Ward-Takahashi identities and making a ``local potential approximation,'' we are able to calculate non-universal quantities such as the effective firing rate nonlinearity of the network, allowing improved quantitative estimates of network statistics. We also derive the dimensionless flow equation that admits universal critical points in the renormalization group flow of the model, and identify two important types of critical points: in networks with an absorbing state there is Directed Percolation (DP) fixed point corresponding to a non-equilibrium phase transition between sustained activity and extinction of activity, and in spontaneously active networks there is a \emph{complex valued} critical point, corresponding to a spinodal transition observed, e.g., in the Lee-Yang ϕ3\phi^3 model of Ising magnets with explicitly broken symmetry. Our Ward-Takahashi identities imply trivial dynamical exponents z=2z_\ast = 2 in both cases, rendering it unclear whether these critical points fall into the known DP or Ising universality classes

    Differences in well-being:the biological and environmental causes, related phenotypes, and real-time assessment

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    Well-being is a complex, and multifaceted construct that includes feeling good and functioning well. There is a growing global recognition of well-being as an important research topic and public policy goal. Well-being is related to less behavioral and emotional problems, and is associated with many positive aspects of daily life, including longevity, higher educational achievement, happier marriage, and more productivity at work. People differ in their levels of well-being, i.e., some people are in general happier or more satisfied with their lives than others. These individual differences in well-being can arise from many different factors, including biological (genetic) influences and environmental influences. To enhance the development of future mental health prevention and intervention strategies to increase well-being, more knowledge about these determinants and factors underlying well-being is needed. In this dissertation, I aimed to increase the understanding of the etiology in a series of studies using different methods, including systematic reviews, meta-analyses, twin designs, and molecular genetic designs. In part I, we brought together all published studies on the neural and physiological factors underlying well-being. This overview allowed us to critically investigate the claims made about the biology involved in well-being. The number of studies on the neural and physiological factors underlying well-being is increasing and the results point towards potential correlates of well-being. However, samples are often still small, and studies focus mostly on a single biomarker. Therefore, more well-powered, data-driven, and integrative studies across biological categories are needed to better understand the neural and physiological pathways that play a role in well-being. In part II, we investigated the overlap between well-being and a range of other phenotypes to learn more about the etiology of well-being. We report a large overlap with phenotypes including optimism, resilience, and depressive symptoms. Furthermore, when removing the genetic overlap between well-being and depressive symptoms, we showed that well-being has unique genetic associations with a range of phenotypes, independently from depressive symptoms. These results can be helpful in designing more effective interventions to increase well-being, taking into account the overlap and possible causality with other phenotypes. In part III, we used the extreme environmental change during the COVID-19 pandemic to investigate individual differences in the effects of such environmental changes on well-being. On average, we found a negative effect of the pandemic on different aspects of well-being, especially further into the pandemic. Whereas most previous studies only looked at this average negative effect of the pandemic on well-being, we focused on the individual differences as well. We reported large individual differences in the effects of the pandemic on well-being in both chapters. This indicates that one-size-fits-all preventions or interventions to maintain or increase well-being during the pandemic or lockdowns will not be successful for the whole population. Further research is needed for the identification of protective factors and resilience mechanisms to prevent further inequality during extreme environmental situations. In part IV, we looked at the real-time assessment of well-being, investigating the feasibility and results of previous studies. The real-time assessment of well-being, related variables, and the environment can lead to new insights about well-being, i.e., results that we cannot capture with traditional survey research. The real-time assessment of well-being is therefore a promising area for future research to unravel the dynamic nature of well-being fluctuations and the interaction with the environment in daily life. Integrating all results in this dissertation confirmed that well-being is a complex human trait that is influenced by many interrelated and interacting factors. Future directions to understand individual differences in well-being will be a data-driven approach to investigate the complex interplay of neural, physiological, genetic, and environmental factors in well-being

    Pairwise versus mutual independence: visualisation, actuarial applications and central limit theorems

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    Accurately capturing the dependence between risks, if it exists, is an increasingly relevant topic of actuarial research. In recent years, several authors have started to relax the traditional 'independence assumption', in a variety of actuarial settings. While it is known that 'mutual independence' between random variables is not equivalent to their 'pairwise independence', this thesis aims to provide a better understanding of the materiality of this difference. The distinction between mutual and pairwise independence matters because, in practice, dependence is often assessed via pairs only, e.g., through correlation matrices, rank-based measures of association, scatterplot matrices, heat-maps, etc. Using such pairwise methods, it is possible to miss some forms of dependence. In this thesis, we explore how material the difference between pairwise and mutual independence is, and from several angles. We provide relevant background and motivation for this thesis in Chapter 1, then conduct a literature review in Chapter 2. In Chapter 3, we focus on visualising the difference between pairwise and mutual independence. To do so, we propose a series of theoretical examples (some of them new) where random variables are pairwise independent but (mutually) dependent, in short, PIBD. We then develop new visualisation tools and use them to illustrate what PIBD variables can look like. We showcase that the dependence involved is possibly very strong. We also use our visualisation tools to identify subtle forms of dependence, which would otherwise be hard to detect. In Chapter 4, we review common dependence models (such has elliptical distributions and Archimedean copulas) used in actuarial science and show that they do not allow for the possibility of PIBD data. We also investigate concrete consequences of the 'nonequivalence' between pairwise and mutual independence. We establish that many results which hold for mutually independent variables do not hold under sole pairwise independent. Those include results about finite sums of random variables, extreme value theory and bootstrap methods. This part thus illustrates what can potentially 'go wrong' if one assumes mutual independence where only pairwise independence holds. Lastly, in Chapters 5 and 6, we investigate the question of what happens for PIBD variables 'in the limit', i.e., when the sample size goes to infi nity. We want to see if the 'problems' caused by dependence vanish for sufficiently large samples. This is a broad question, and we concentrate on the important classical Central Limit Theorem (CLT), for which we fi nd that the answer is largely negative. In particular, we construct new sequences of PIBD variables (with arbitrary margins) for which a CLT does not hold. We derive explicitly the asymptotic distribution of the standardised mean of our sequences, which allows us to illustrate the extent of the 'failure' of a CLT for PIBD variables. We also propose a general methodology to construct dependent K-tuplewise independent (K an arbitrary integer) sequences of random variables with arbitrary margins. In the case K = 3, we use this methodology to derive explicit examples of triplewise independent sequences for which no CLT hold. Those results illustrate that mutual independence is a crucial assumption within CLTs, and that having larger samples is not always a viable solution to the problem of non-independent data
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