SonoNet: Real-Time Detection and Localisation of Fetal Standard Scan Planes in Freehand Ultrasound

Identifying and interpreting fetal standard scan planes during 2D ultrasound mid-pregnancy examinations are highly complex tasks which require years of training. Apart from guiding the probe to the correct location, it can be equally difficult for a non-expert to identify relevant structures within the image. Automatic image processing can provide tools to help experienced as well as inexperienced operators with these tasks. In this paper, we propose a novel method based on convolutional neural networks which can automatically detect 13 fetal standard views in freehand 2D ultrasound data as well as provide a localisation of the fetal structures via a bounding box. An important contribution is that the network learns to localise the target anatomy using weak supervision based on image-level labels only. The network architecture is designed to operate in real-time while providing optimal output for the localisation task. We present results for real-time annotation, retrospective frame retrieval from saved videos, and localisation on a very large and challenging dataset consisting of images and video recordings of full clinical anomaly screenings. We found that the proposed method achieved an average F1-score of 0.798 in a realistic classification experiment modelling real-time detection, and obtained a 90.09% accuracy for retrospective frame retrieval. Moreover, an accuracy of 77.8% was achieved on the localisation task.Comment: 12 pages, 8 figures, published in IEEE Transactions in Medical Imagin

Text-detection and -recognition from natural images

Text detection and recognition from images could have numerous functional applications for document analysis, such as assistance for visually impaired people; recognition of vehicle license plates; evaluation of articles containing tables, street signs, maps, and diagrams; keyword-based image exploration; document retrieval; recognition of parts within industrial automation; content-based extraction; object recognition; address block location; and text-based video indexing. This research exploited the advantages of artificial intelligence (AI) to detect and recognise text from natural images. Machine learning and deep learning were used to accomplish this task.In this research, we conducted an in-depth literature review on the current detection and recognition methods used by researchers to identify the existing challenges, wherein the differences in text resulting from disparity in alignment, style, size, and orientation combined with low image contrast and a complex background make automatic text extraction a considerably challenging and problematic task. Therefore, the state-of-the-art suggested approaches obtain low detection rates (often less than 80%) and recognition rates (often less than 60%). This has led to the development of new approaches. The aim of the study was to develop a robust text detection and recognition method from natural images with high accuracy and recall, which would be used as the target of the experiments. This method could detect all the text in the scene images, despite certain specific features associated with the text pattern. Furthermore, we aimed to find a solution to the two main problems concerning arbitrarily shaped text (horizontal, multi-oriented, and curved text) detection and recognition in a low-resolution scene and with various scales and of different sizes.In this research, we propose a methodology to handle the problem of text detection by using novel combination and selection features to deal with the classification algorithms of the text/non-text regions. The text-region candidates were extracted from the grey-scale images by using the MSER technique. A machine learning-based method was then applied to refine and validate the initial detection. The effectiveness of the features based on the aspect ratio, GLCM, LBP, and HOG descriptors was investigated. The text-region classifiers of MLP, SVM, and RF were trained using selections of these features and their combinations. The publicly available datasets ICDAR 2003 and ICDAR 2011 were used to evaluate the proposed method. This method achieved the state-of-the-art performance by using machine learning methodologies on both databases, and the improvements were significant in terms of Precision, Recall, and F-measure. The F-measure for ICDAR 2003 and ICDAR 2011 was 81% and 84%, respectively. The results showed that the use of a suitable feature combination and selection approach could significantly increase the accuracy of the algorithms.A new dataset has been proposed to fill the gap of character-level annotation and the availability of text in different orientations and of curved text. The proposed dataset was created particularly for deep learning methods which require a massive completed and varying range of training data. The proposed dataset includes 2,100 images annotated at the character and word levels to obtain 38,500 samples of English characters and 12,500 words. Furthermore, an augmentation tool has been proposed to support the proposed dataset. The missing of object detection augmentation tool encroach to proposed tool which has the ability to update the position of bounding boxes after applying transformations on images. This technique helps to increase the number of samples in the dataset and reduce the time of annotations where no annotation is required. The final part of the thesis presents a novel approach for text spotting, which is a new framework for an end-to-end character detection and recognition system designed using an improved SSD convolutional neural network, wherein layers are added to the SSD networks and the aspect ratio of the characters is considered because it is different from that of the other objects. Compared with the other methods considered, the proposed method could detect and recognise characters by training the end-to-end model completely. The performance of the proposed method was better on the proposed dataset; it was 90.34. Furthermore, the F-measure of the method’s accuracy on ICDAR 2015, ICDAR 2013, and SVT was 84.5, 91.9, and 54.8, respectively. On ICDAR13, the method achieved the second-best accuracy. The proposed method could spot text in arbitrarily shaped (horizontal, oriented, and curved) scene text.</div

Active Learning Strategies for Phenotypic Profiling of High-Content Screens

Abstract High-content screening is a powerful method to discover new drugs and carry out basic biological research. Increasingly, high-content screens have come to rely on supervised machine learning (SML) to perform automatic phenotypic classification as an essential step of the analysis. However, this comes at a cost, namely, the labeled examples required to train the predictive model. Classification performance increases with the number of labeled examples, and because labeling examples demands time from an expert, the training process represents a significant time investment. Active learning strategies attempt to overcome this bottleneck by presenting the most relevant examples to the annotator, thereby achieving high accuracy while minimizing the cost of obtaining labeled data. In this article, we investigate the impact of active learning on single-cell–based phenotype recognition, using data from three large-scale RNA interference high-content screens representing diverse phenotypic profiling problems. We consider several combinations of active learning strategies and popular SML methods. Our results show that active learning significantly reduces the time cost and can be used to reveal the same phenotypic targets identified using SML. We also identify combinations of active learning strategies and SML methods which perform better than others on the phenotypic profiling problems we studied