Indispensability arguments in favour of reductive explanations

Instances of explanatory reduction are often advocated on metaphysical grounds; given that the only real things in the world are subatomic particles and their interaction, we have to try to explain everything in terms of the laws of physics. In this paper, we show that explanatory reduction cannot be defended on metaphysical grounds. Nevertheless, indispensability arguments for reductive explanations can be developed, taking into account actual scientific practice and the role of epistemic interests. Reductive explanations might be indispensable to address some epistemic interest answering a specific explanation-seeking question in the most accurate, adequate and efficient way. Just like explanatory pluralists often advocate the indispensability of higher levels of explanation pointing at the pragmatic value of the explanatory information obtained on these higher levels, we argue that explanatory reduction – traditionally understood as the contender of pluralism – can be defended in a similar way. The pragmatic value reductionist, lower level explanations might have in the biomedical sciences and the social sciences is illustrated by some case studies

Information Outlook, May 2006

Volume 10, Issue 5https://scholarworks.sjsu.edu/sla_io_2006/1004/thumbnail.jp

Information Outlook, May 2006

Volume 10, Issue 5https://scholarworks.sjsu.edu/sla_io_2006/1004/thumbnail.jp

Three Ways of Resisting Racism

Two widespread strategies of resisting racism are the following. The first one is to deny the existence of races and thus block even the possibility of racist claims. The second one is to grant that races exist but insist that racial differences do not imply value differences. The aim of this paper is to outline a strategy of resisting racism that is weaker than the first but stronger than the second strategy: even if we accept that races exist, we can still deny that there are projectible racial differences. And this is enough to block the possibility of racist claims without appealing to the slippery topic of value differences. I use some considerations from philosophy of biology in order to argue for this claim

Ethical perspectives on advances in biogerontology

Worldwide populations are aging with economic development as a result of public health initiatives and advances in therapeutic discoveries. Since 1850, life expectancy has advanced by 1 year for every four. Accompanying this change is the rapid development of anti‐aging science. There are three schools of thought in the field of aging science. One perspective is the life course approach, which considers that aging is a good and natural process to be embraced as a necessary and positive aspect of life, where the aim is to improve the quality of existing lifespan and “compress” morbidity. Another view is that aging is undesirable, and that rejuvenation and indeed immortality are possible since the biological basis of aging is understood, and therefore, strategies are possible for engineering negligible senescence. Finally, a hybrid approach is that life span can be extended by anti‐aging medicines but with uncertain effects on health. While these advances offer much promise, the ethical perspectives are seldom discussed in cross‐disciplinary settings. This article discusses some of the key ethical issues arising from recent advances in biogerontology

Is a gene-centric human proteome project the best way for proteomics to serve biology?

With the recent developments in proteomic technologies, a complete human proteome project (HPP) appears feasible for the first time. However, there is still debate as to how it should be designed and what it should encompass. In "proteomics speak", the debate revolves around the central question as to whether a gene-centric or a protein-centric proteomics approach is the most appropriate way forward. In this paper, we try to shed light on what these definitions mean, how large-scale proteomics such as a HPP can insert into the larger omics chorus, and what we can reasonably expect from a HPP in the way it has been proposed so far