3,204 research outputs found

    QuASeR -- Quantum Accelerated De Novo DNA Sequence Reconstruction

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    In this article, we present QuASeR, a reference-free DNA sequence reconstruction implementation via de novo assembly on both gate-based and quantum annealing platforms. Each one of the four steps of the implementation (TSP, QUBO, Hamiltonians and QAOA) is explained with simple proof-of-concept examples to target both the genomics research community and quantum application developers in a self-contained manner. The details of the implementation are discussed for the various layers of the quantum full-stack accelerator design. We also highlight the limitations of current classical simulation and available quantum hardware systems. The implementation is open-source and can be found on https://github.com/prince-ph0en1x/QuASeR.Comment: 24 page

    Performance comparison of various probability gate assisted binary lightning search algorithm

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    Recently, many new nature-inspired optimization algorithms have been introduced to further enhance the computational intelligence optimization algorithms. Among them, lightning search algorithm (LSA) is a recent heuristic optimization method for resolving continuous problems. It mimics the natural phenomenon of lightning to find out the global optimal solution around the search space. In this paper, a suitable technique to formulate binary version of lightning search algorithm (BLSA) is presented. Three common probability transfer functions, namely, logistic sigmoid, tangent hyperbolic sigmoid and quantum bit rotating gate are investigated to be utilized in the original LSA. The performances of three transfer functions based BLSA is evaluated using various standard functions with different features and the results are compared with other four famous heuristic optimization techniques. The comparative study clearly reveals that tangent hyperbolic transfer function is the most suitable function that can be utilized in the binary version of LSA

    Portfolio Optimisation Using the D-Wave Quantum Annealer

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    The first quantum computers are expected to perform well at quadratic optimisation problems. In this paper a quadratic problem in finance is taken, the Portfolio Optimisation problem. Here, a set of assets is chosen for investment, such that the total risk is minimised, a minimum return is realised and a budget constraint is met. This problem is solved for several instances in two main indices, the Nikkei225 and the S\&P500 index, using the state-of-the-art implementation of D-Wave's quantum annealer and its hybrid solvers. The results are benchmarked against conventional, state-of-the-art, commercially available tooling. Results show that for problems of the size of the used instances, the D-Wave solution, in its current, still limited size, comes already close to the performance of commercial solvers.Comment: 14 pages, 1 figur
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