43 research outputs found

    LIPIcs, Volume 251, ITCS 2023, Complete Volume

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    LIPIcs, Volume 251, ITCS 2023, Complete Volum

    LIPIcs, Volume 261, ICALP 2023, Complete Volume

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    LIPIcs, Volume 261, ICALP 2023, Complete Volum

    Novel Strategies in Ischemic Heart Disease

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    The first edition of this book will provide a comprehensive overview of ischemic heart disease, including epidemiology, risk factors, pathogenesis, clinical presentation, diagnostic tests, differential diagnosis, treatment, complications and prognosis. Also discussed are current treatment options, protocols and diagnostic procedures, as well as the latest advances in the field. The book will serve as a cutting-edge point of reference for the basic or clinical researcher, and any clinician involved in the diagnosis and management of ischemic heart disease. This book is essentially designed to fill the vital gap existing between these practices, to provide a textbook that is substantial and readable, compact and reasonably comprehensive, and to provide an excellent blend of "basics to bedside and beyond" in the field of ischemic heart disease. The book also covers the future novel treatment strategies, focusing on the basic scientific and clinical aspects of the diagnosis and management of ischemic heart disease

    Fire

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    Vegetation plays a crucial role in regulating environmental conditions, including weather and climate. The amount of water and carbon dioxide in the air and the albedo of our planet are all influenced by vegetation, which in turn influences all life on Earth. Soil properties are also strongly influenced by vegetation, through biogeochemical cycles and feedback loops (see Volume 1A—Section 4). Vegetated landscapes on Earth provide habitat and energy for a rich diversity of animal species, including humans. Vegetation is also a major component of the world economy, through the global production of food, fibre, fuel, medicine, and other plantbased resources for human consumptio

    Orthogeriatrics

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    This new open access edition supported by the Fragility Fracture Network aims at giving the widest possible dissemination on fragility fracture (especially hip fracture) management and notably in countries where this expertise is sorely needed. It has been extensively revised and updated by the experts of this network to provide a unique and reliable content in one single volume. Throughout the book, attention is given to the difficult question of how to provide best practice in countries where the discipline of geriatric medicine is not well established and resources for secondary prevention are scarce. The revised and updated chapters on the epidemiology of hip fractures, osteoporosis, sarcopenia, surgery, anaesthesia, medical management of frailty, peri-operative complications, rehabilitation and nursing are supplemented by six new chapters. These include an overview of the multidisciplinary approach to fragility fractures and new contributions on pre-hospital care, treatment in the emergency room, falls prevention, nutrition and systems for audit. The reader will have an exhaustive overview and will gain essential, practical knowledge on how best to manage fractures in elderly patients and how to develop clinical systems that do so reliably

    Evaluating the impact of tree provenance, tree phenotype and emergent disease on microbial and insect populations in tree ecosystems

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    Trees host complex microhabitats, supporting a wide diversity of organisms. This study focuses on two of these communities: the insect herbivores and the microbial endophytes. Studies in the field of community genetics have demonstrated that intraspecific genetic variation in a foundation species can have cascading effects on the composition and diversity of associated communities. Using a provenance trial, which excludes confounding environmental factors, the effects of tree phenotypic traits on the insect herbivore and microbial endophytic community were tested, in the first instance, using the Quercus study system. A leaf morphometric analysis allowed for accurate differentiation of the two native oak species, Quercus robur and Q. petraea. Interspecific variation in the composition of insect herbivore species and in the composition of bacterial and fungal endophyte species were recorded in the two oak species for the first time. The plant vigour hypothesis, which states that insect herbivores would preferentially feed on the most vigorous plant, was supported by the galling and mining insect feeding guilds in this study system but had varying effects on the endophytic species. Tree budburst phenology, another phenotypic trait, also had varying effects on the abundance of insects and endophytes. Quercus trees in the UK are expected to experience profound changes in climate. In an effort to maintain oak species, assisted migration schemes may be implemented, which involves the planting of seed stock from exotic provenances that match the predicted climate of the planting site in 50-100 years. This study considers the effect of this approach on the associated biodiversity. Insect and endophyte composition, richness and diversity were not strongly correlated with tree provenance, so it seems unlikely that climate matching strategies would strongly negatively impact these associated communities. As the UK climate warms, walnut trees (Juglans spp.) may become a more commercially viable source of hardwood timber. This study characterised the endophytic community of two introduced walnut trees in the UK: Juglans nigra and J. regia. A number of latent pathogenic fungi and bacteria were associated with asymptomatic tissues of both Quercus and Juglans, these species have the potential to cause disease if the tree is subjected to stress such as climate change and should therefore be monitored. Finally, the effect of a decline syndrome, Acute Oak Decline (AOD) which causes bleeding cankers among other symptoms on native oak species in the UK, on the endophytic community of oak was recorded. Bacterial endophyte communities did not differ between symptomatic and asymptomatic trees. However, differences in the fungal endophytic community associated with the inner bark of trees showing symptoms of AOD were significantly different from asymptomatic trees. This result suggests that (1) there could be a fungal component(s) to AOD that has not been reported or (2) asymptomatic trees harbour beneficial fungal endophytes that protect against AOD

    Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

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    These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical aspects of flow cytometry enabling immunologists to avoid the common errors that often undermine immunological data. Notably, there are comprehensive sections of all major immune cell types with helpful Tables detailing phenotypes in murine and human cells. The latest flow cytometry techniques and applications are also described, featuring examples of the data that can be generated and, importantly, how the data can be analysed. Furthermore, there are sections detailing tips, tricks and pitfalls to avoid, all written and peer-reviewed by leading experts in the field, making this an essential research companion

    Generalized averaged Gaussian quadrature and applications

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    A simple numerical method for constructing the optimal generalized averaged Gaussian quadrature formulas will be presented. These formulas exist in many cases in which real positive GaussKronrod formulas do not exist, and can be used as an adequate alternative in order to estimate the error of a Gaussian rule. We also investigate the conditions under which the optimal averaged Gaussian quadrature formulas and their truncated variants are internal
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