3,485 research outputs found

    Graduate Catalog of Studies, 2023-2024

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    Securing NextG networks with physical-layer key generation: A survey

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    As the development of next-generation (NextG) communication networks continues, tremendous devices are accessing the network and the amount of information is exploding. However, with the increase of sensitive data that requires confidentiality to be transmitted and stored in the network, wireless network security risks are further amplified. Physical-layer key generation (PKG) has received extensive attention in security research due to its solid information-theoretic security proof, ease of implementation, and low cost. Nevertheless, the applications of PKG in the NextG networks are still in the preliminary exploration stage. Therefore, we survey existing research and discuss (1) the performance advantages of PKG compared to cryptography schemes, (2) the principles and processes of PKG, as well as research progresses in previous network environments, and (3) new application scenarios and development potential for PKG in NextG communication networks, particularly analyzing the effect and prospects of PKG in massive multiple-input multiple-output (MIMO), reconfigurable intelligent surfaces (RISs), artificial intelligence (AI) enabled networks, integrated space-air-ground network, and quantum communication. Moreover, we summarize open issues and provide new insights into the development trends of PKG in NextG networks

    Principles of generalization for sensorimotor cerebellar learning

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    Dataflow Programming and Acceleration of Computationally-Intensive Algorithms

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    The volume of unstructured textual information continues to grow due to recent technological advancements. This resulted in an exponential growth of information generated in various formats, including blogs, posts, social networking, and enterprise documents. Numerous Enterprise Architecture (EA) documents are also created daily, such as reports, contracts, agreements, frameworks, architecture requirements, designs, and operational guides. The processing and computation of this massive amount of unstructured information necessitate substantial computing capabilities and the implementation of new techniques. It is critical to manage this unstructured information through a centralized knowledge management platform. Knowledge management is the process of managing information within an organization. This involves creating, collecting, organizing, and storing information in a way that makes it easily accessible and usable. The research involved the development textual knowledge management system, and two use cases were considered for extracting textual knowledge from documents. The first case study focused on the safety-critical documents of a railway enterprise. Safety is of paramount importance in the railway industry. There are several EA documents including manuals, operational procedures, and technical guidelines that contain critical information. Digitalization of these documents is essential for analysing vast amounts of textual knowledge that exist in these documents to improve the safety and security of railway operations. A case study was conducted between the University of Huddersfield and the Railway Safety Standard Board (RSSB) to analyse EA safety documents using Natural language processing (NLP). A graphical user interface was developed that includes various document processing features such as semantic search, document mapping, text summarization, and visualization of key trends. For the second case study, open-source data was utilized, and textual knowledge was extracted. Several features were also developed, including kernel distribution, analysis offkey trends, and sentiment analysis of words (such as unique, positive, and negative) within the documents. Additionally, a heterogeneous framework was designed using CPU/GPU and FPGAs to analyse the computational performance of document mapping

    Graduate Catalog of Studies, 2023-2024

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    Principles of generalization for sensorimotor cerebellar learning

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    Comparison of Various Machine Learning Models for Estimating Construction Projects Sales Valuation Using Economic Variables and Indices

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    The capability of various machine learning techniques in predicting construction project profit in residential buildings using a combination of economic variables and indices (EV&Is) and physical and financial variables (P&F) as input variables remain uncertain. Although recent studies have primarily focused on identifying the factors influencing the sales of construction projects due to their significant short-term impact on a country's economy, the prediction of these parameters is crucial for ensuring project sustainability. While techniques such as regression and artificial neural networks have been utilized to estimate construction project sales, limited research has been conducted in this area. The application of machine learning techniques presents several advantages over conventional methods, including reductions in cost, time, and effort. Therefore, this study aims to predict the sales valuation of construction projects using various machine learning approaches, incorporating different EV&Is and P&F as input features for these models and subsequently generating the sales valuation as the output. This research will undertake a comparative analysis to investigate the efficiency of the different machine learning models, identifying the most effective approach for estimating the sales valuation of construction projects. By leveraging machine learning techniques, it is anticipated that the accuracy of sales valuation predictions will be enhanced, ultimately resulting in more sustainable and successful construction projects. In general, the findings of this research reveal that the extremely randomized trees model delivers the best performance, while the decision tree model exhibits the least satisfactory performance in predicting the sales valuation of construction projects

    Resource-aware scheduling for 2D/3D multi-/many-core processor-memory systems

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    This dissertation addresses the complexities of 2D/3D multi-/many-core processor-memory systems, focusing on two key areas: enhancing timing predictability in real-time multi-core processors and optimizing performance within thermal constraints. The integration of an increasing number of transistors into compact chip designs, while boosting computational capacity, presents challenges in resource contention and thermal management. The first part of the thesis improves timing predictability. We enhance shared cache interference analysis for set-associative caches, advancing the calculation of Worst-Case Execution Time (WCET). This development enables accurate assessment of cache interference and the effectiveness of partitioned schedulers in real-world scenarios. We introduce TCPS, a novel task and cache-aware partitioned scheduler that optimizes cache partitioning based on task-specific WCET sensitivity, leading to improved schedulability and predictability. Our research explores various cache and scheduling configurations, providing insights into their performance trade-offs. The second part focuses on thermal management in 2D/3D many-core systems. Recognizing the limitations of Dynamic Voltage and Frequency Scaling (DVFS) in S-NUCA many-core processors, we propose synchronous thread migrations as a thermal management strategy. This approach culminates in the HotPotato scheduler, which balances performance and thermal safety. We also introduce 3D-TTP, a transient temperature-aware power budgeting strategy for 3D-stacked systems, reducing the need for Dynamic Thermal Management (DTM) activation. Finally, we present 3QUTM, a novel method for 3D-stacked systems that combines core DVFS and memory bank Low Power Modes with a learning algorithm, optimizing response times within thermal limits. This research contributes significantly to enhancing performance and thermal management in advanced processor-memory systems

    The development of bioinformatics workflows to explore single-cell multi-omics data from T and B lymphocytes

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    The adaptive immune response is responsible for recognising, containing and eliminating viral infection, and protecting from further reinfection. This antigen-specific response is driven by T and B cells, which recognise antigenic epitopes via highly specific heterodimeric surface receptors, termed T-cell receptors (TCRs) and B cell receptors (BCRs). The theoretical diversity of the receptor repertoire that can be generated via homologous recombination of V, D and J genes is large enough (>1015 unique sequences) that virtually any antigen can be recognised. However, only a subset of these are generated within the human body, and how they succeed in specifically recognising any pathogen(s) and distinguishing these from self-proteins remains largely unresolved. The recent advances in applying single-cell genomics technologies to simultaneously measure the clonality, surface phenotype and transcriptomic signature of pathogen- specific immune cells have significantly improved understanding of these questions. Single-cell multi-omics permits the accurate identification of clonally expanded populations, their differentiation trajectories, the level of immune receptor repertoire diversity involved in the response and the phenotypic and molecular heterogeneity. This thesis aims to develop a bioinformatic workflow utilising single-cell multi-omics data to explore, quantify and predict the clonal and transcriptomic signatures of the human T-cell response during and following viral infection. In the first aim, a web application, VDJView, was developed to facilitate the simultaneous analysis and visualisation of clonal, transcriptomic and clinical metadata of T and B cell multi-omics data. The application permits non-bioinformaticians to perform quality control and common analyses of single-cell genomics data integrated with other metadata, thus permitting the identification of biologically and clinically relevant parameters. The second aim pertains to analysing the functional, molecular and immune receptor profiles of CD8+ T cells in the acute phase of primary hepatitis C virus (HCV) infection. This analysis identified a novel population of progenitors of exhausted T cells, and lineage tracing revealed distinct trajectories with multiple fates and evolutionary plasticity. Furthermore, it was observed that high-magnitude IFN-γ CD8+ T-cell response is associated with the increased probability of viral escape and chronic infection. Finally, in the third aim, a novel analysis is presented based on the topological characteristics of a network generated on pathogen-specific, paired-chain, CD8+ TCRs. This analysis revealed how some cross-reactivity between TCRs can be explained via the sequence similarity between TCRs and that this property is not uniformly distributed across all pathogen-specific TCR repertoires. Strong correlations between the topological properties of the network and the biological properties of the TCR sequences were identified and highlighted. The suite of workflows and methods presented in this thesis are designed to be adaptable to various T and B cell multi-omic datasets. The associated analyses contribute to understanding the role of T and B cells in the adaptive immune response to viral-infection and cancer
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