On Interpretability of Deep Learning based Skin Lesion Classifiers using Concept Activation Vectors

Deep learning based medical image classifiers have shown remarkable prowess in various application areas like ophthalmology, dermatology, pathology, and radiology. However, the acceptance of these Computer-Aided Diagnosis (CAD) systems in real clinical setups is severely limited primarily because their decision-making process remains largely obscure. This work aims at elucidating a deep learning based medical image classifier by verifying that the model learns and utilizes similar disease-related concepts as described and employed by dermatologists. We used a well-trained and high performing neural network developed by REasoning for COmplex Data (RECOD) Lab for classification of three skin tumours, i.e. Melanocytic Naevi, Melanoma and Seborrheic Keratosis and performed a detailed analysis on its latent space. Two well established and publicly available skin disease datasets, PH2 and derm7pt, are used for experimentation. Human understandable concepts are mapped to RECOD image classification model with the help of Concept Activation Vectors (CAVs), introducing a novel training and significance testing paradigm for CAVs. Our results on an independent evaluation set clearly shows that the classifier learns and encodes human understandable concepts in its latent representation. Additionally, TCAV scores (Testing with CAVs) suggest that the neural network indeed makes use of disease-related concepts in the correct way when making predictions. We anticipate that this work can not only increase confidence of medical practitioners on CAD but also serve as a stepping stone for further development of CAV-based neural network interpretation methods.Comment: Accepted for the IEEE International Joint Conference on Neural Networks (IJCNN) 202

Quick and (not so) Dirty: Unsupervised Selection of Justification Sentences for Multi-hop Question Answering

We propose an unsupervised strategy for the selection of justification sentences for multi-hop question answering (QA) that (a) maximizes the relevance of the selected sentences, (b) minimizes the overlap between the selected facts, and (c) maximizes the coverage of both question and answer. This unsupervised sentence selection method can be coupled with any supervised QA approach. We show that the sentences selected by our method improve the performance of a state-of-the-art supervised QA model on two multi-hop QA datasets: AI2's Reasoning Challenge (ARC) and Multi-Sentence Reading Comprehension (MultiRC). We obtain new state-of-the-art performance on both datasets among approaches that do not use external resources for training the QA system: 56.82% F1 on ARC (41.24% on Challenge and 64.49% on Easy) and 26.1% EM0 on MultiRC. Our justification sentences have higher quality than the justifications selected by a strong information retrieval baseline, e.g., by 5.4% F1 in MultiRC. We also show that our unsupervised selection of justification sentences is more stable across domains than a state-of-the-art supervised sentence selection method.Comment: Published at EMNLP-IJCNLP 2019 as long conference paper. Corrected the name reference for Speer et.al, 201

Unsupervised Alignment-based Iterative Evidence Retrieval for Multi-hop Question Answering

Evidence retrieval is a critical stage of question answering (QA), necessary not only to improve performance, but also to explain the decisions of the corresponding QA method. We introduce a simple, fast, and unsupervised iterative evidence retrieval method, which relies on three ideas: (a) an unsupervised alignment approach to soft-align questions and answers with justification sentences using only GloVe embeddings, (b) an iterative process that reformulates queries focusing on terms that are not covered by existing justifications, which (c) a stopping criterion that terminates retrieval when the terms in the given question and candidate answers are covered by the retrieved justifications. Despite its simplicity, our approach outperforms all the previous methods (including supervised methods) on the evidence selection task on two datasets: MultiRC and QASC. When these evidence sentences are fed into a RoBERTa answer classification component, we achieve state-of-the-art QA performance on these two datasets.Comment: Accepted at ACL 2020 as a long conference pape

Prediction model of alcohol intoxication from facial temperature dynamics based on K-means clustering driven by evolutionary computing

Alcohol intoxication is a significant phenomenon, affecting many social areas, including work procedures or car driving. Alcohol causes certain side effects including changing the facial thermal distribution, which may enable the contactless identification and classification of alcohol-intoxicated people. We adopted a multiregional segmentation procedure to identify and classify symmetrical facial features, which reliably reflects the facial-temperature variations while subjects are drinking alcohol. Such a model can objectively track alcohol intoxication in the form of a facial temperature map. In our paper, we propose the segmentation model based on the clustering algorithm, which is driven by the modified version of the Artificial Bee Colony (ABC) evolutionary optimization with the goal of facial temperature features extraction from the IR (infrared radiation) images. This model allows for a definition of symmetric clusters, identifying facial temperature structures corresponding with intoxication. The ABC algorithm serves as an optimization process for an optimal cluster's distribution to the clustering method the best approximate individual areas linked with gradual alcohol intoxication. In our analysis, we analyzed a set of twenty volunteers, who had IR images taken to reflect the process of alcohol intoxication. The proposed method was represented by multiregional segmentation, allowing for classification of the individual spatial temperature areas into segmentation classes. The proposed method, besides single IR image modelling, allows for dynamical tracking of the alcohol-temperature features within a process of intoxication, from the sober state up to the maximum observed intoxication level.Web of Science118art. no. 99