A Method for Neuronal Source Identification

Multi-sensor microelectrodes for extracellular action potential recording have significantly improved the quality of in vivo recorded neuronal signals. These microelectrodes have also been instrumental in the localization of neuronal signal sources. However, existing neuron localization methods have been mostly utilized in vivo, where the true neuron location remains unknown. Therefore, these methods could not be experimentally validated. This article presents experimental validation of a method capable of estimating both the location and intensity of an electrical signal source. A four-sensor microelectrode (tetrode) immersed in a saline solution was used to record stimulus patterns at multiple intensity levels generated by a stimulating electrode. The location of the tetrode was varied with respect to the stimulator. The location and intensity of the stimulator were estimated using the Multiple Signal Classification (MUSIC) algorithm, and the results were quantified by comparison to the true values. The localization results, with an accuracy and precision of ~ 10 microns, and ~ 11 microns respectively, imply that MUSIC can resolve individual neuronal sources. Similarly, source intensity estimations indicate that this approach can track changes in signal amplitude over time. Together, these results suggest that MUSIC can be used to characterize neuronal signal sources in vivo.Comment: 14 pages, 5 figure

Low cost underwater acoustic localization

Over the course of the last decade, the cost of marine robotic platforms has significantly decreased. In part this has lowered the barriers to entry of exploring and monitoring larger areas of the earth's oceans. However, these advances have been mostly focused on autonomous surface vehicles (ASVs) or shallow water autonomous underwater vehicles (AUVs). One of the main drivers for high cost in the deep water domain is the challenge of localizing such vehicles using acoustics. A low cost one-way travel time underwater ranging system is proposed to assist in localizing deep water submersibles. The system consists of location aware anchor buoys at the surface and underwater nodes. This paper presents a comparison of methods together with details on the physical implementation to allow its integration into a deep sea micro AUV currently in development. Additional simulation results show error reductions by a factor of three.Comment: 73rd Meeting of the Acoustical Society of Americ

MScMS-II: an innovative IR-based indoor coordinate measuring system for large-scale metrology applications

According to the current great interest concerning large-scale metrology applications in many different fields of manufacturing industry, technologies and techniques for dimensional measurement have recently shown a substantial improvement. Ease-of-use, logistic and economic issues, as well as metrological performance are assuming a more and more important role among system requirements. This paper describes the architecture and the working principles of a novel infrared (IR) optical-based system, designed to perform low-cost and easy indoor coordinate measurements of large-size objects. The system consists of a distributed network-based layout, whose modularity allows fitting differently sized and shaped working volumes by adequately increasing the number of sensing units. Differently from existing spatially distributed metrological instruments, the remote sensor devices are intended to provide embedded data elaboration capabilities, in order to share the overall computational load. The overall system functionalities, including distributed layout configuration, network self-calibration, 3D point localization, and measurement data elaboration, are discussed. A preliminary metrological characterization of system performance, based on experimental testing, is also presente

Nonlinear time-warping made simple: a step-by-step tutorial on underwater acoustic modal separation with a single hydrophone

© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Bonnel, J., Thode, A., Wright, D., & Chapman, R. Nonlinear time-warping made simple: a step-by-step tutorial on underwater acoustic modal separation with a single hydrophone. The Journal of the Acoustical Society of America, 147(3), (2020): 1897, doi:10.1121/10.0000937.Classical ocean acoustic experiments involve the use of synchronized arrays of sensors. However, the need to cover large areas and/or the use of small robotic platforms has evoked interest in single-hydrophone processing methods for localizing a source or characterizing the propagation environment. One such processing method is “warping,” a non-linear, physics-based signal processing tool dedicated to decomposing multipath features of low-frequency transient signals (frequency f  1 km). Since its introduction to the underwater acoustics community in 2010, warping has been adopted in the ocean acoustics literature, mostly as a pre-processing method for single receiver geoacoustic inversion. Warping also has potential applications in other specialties, including bioacoustics; however, the technique can be daunting to many potential users unfamiliar with its intricacies. Consequently, this tutorial article covers basic warping theory, presents simulation examples, and provides practical experimental strategies. Accompanying supplementary material provides matlab code and simulated and experimental datasets for easy implementation of warping on both impulsive and frequency-modulated signals from both biotic and man-made sources. This combined material should provide interested readers with user-friendly resources for implementing warping methods into their own research.This work was supported by the Office of Naval Research (Task Force Ocean, project N00014-19-1-2627) and by the North Pacific Research Board (project 1810). Original warping developments were supported by the French Delegation Generale de l'Armement

Robust Gravitational Wave Burst Detection and Source Localization in a Network of Interferometers Using Cross Wigner Spectra

We discuss a fast cross-Wigner transform based technique for detecting gravitational wave bursts, and estimating the direction of arrival, using a network of (three) non co-located interferometric detectors. The performances of the detector as a function of signal strength and source location, and the accuracy of the direction of arrival estimation are investigated by numerical simulations.Comment: accepted in Class. Quantum Gravit