521,533 research outputs found

    A prospective cohort study comparing the reactogenicity of trivalent influenza vaccine in pregnant and non-pregnant women

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    Background: Influenza vaccination during pregnancy can prevent serious illness in expectant mothers and provide protection to newborns; however, historically uptake has been limited due to a number of factors, including safety concerns. Symptomatic complaints are common during pregnancy and may be mistakenly associated with reactions to trivalent influenza vaccine (TIV). To investigate this, we compared post-vaccination events self-reported by pregnant women to events reported by non-pregnant women receiving TIV. Methods: A prospective cohort of 1,086 pregnant women and 314 non-pregnant female healthcare workers (HCWs) who received TIV between March-May 2014 were followed-up seven days post-vaccination to assess local and systemic adverse events following immunisation (AEFIs). Women were surveyed by text message regarding perceived reactions to TIV. Those reporting an AEFI completed an interview by telephone or mobile phone to ascertain details. Logistic regression models adjusting for age and residence were used to compare reactions reported by pregnant women and non-pregnant HCWs. Results: Similar proportions of pregnant women and non-pregnant, female HCWs reported ≥1 reaction following vaccination with TIV (13.0% and 17.3%, respectively; OR = 1.2 [95% CI: 0.8-1.8]). Non-pregnant, female HCWs were more likely to report fever or headache compared to pregnant women (OR: 4.6 [95% CI 2.1-10.3] and OR: 2.2 [95% CI 1.0-4.6], respectively). No other significant differences in reported symptoms were observed. No serious vaccine-associated adverse events were reported, and less than 2% of each group sought medical advice for a reaction. Conclusions: We found no evidence suggesting pregnant women are more likely to report adverse events following influenza vaccination when compared to non-pregnant female HCWs of similar age, and in some cases, pregnant women reported significantly fewer adverse events. These results further support the safety of TIV administered in pregnant women

    Comparison of Ankle Proprioception Between Pregnant and Non Pregnant Women

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    Pregnant women report falls especially during their third trimester. Physiological changes along with ligament laxity can affect the joint proprioception in this population. This study was conducted to compare the ankle proprioception between pregnant and non pregnant women. Thirty pregnant and 30 non pregnant women were included in the study and the position of ankles were recorded by a digital camera placed 60 cms away from the feet of the subject. UTHSCSA Image tool software version 3.0. was used to measure the difference between the initial and the final angle. The median repositioning error in the pregnant group was 11.6 (7.6, 12.4) degrees and the median repositioning error in the non-pregnant group was 4.2 (2.1, 6.3) degrees. There was a statistically significant difference in ankle joint proprioception between pregnant and non pregnant women

    Testing the surface fixation method in gestational diabetes mellitus

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    Introduction: To test the surface fixation method contrasting urine samples of women with GDM vs healthy pregnant women. Methods: This was a pilot descriptive study. Three groups were conformed: A) Pregnant women with GDM, B) Women with healthy pregnancies and C) Non-pregnant healthy women. The positiveness of the surface fixation method was contrasted with Odds Ratio. Results: 12 women with GDM, 14 with healthy pregnancies and 9 non-pregnant women were included in the study. The OR for a positive surface fixation test when contrasting GDM vs Healthy pregnancies was of 2.7 while the value when contrasting GDM vs Healthy pregnancies + Non pregnant women was of 3.2 without reaching significant statistical difference in any case. Conclusion: the surface fixation method used with urine samples, suggests the existence of a transient antigen-antibody reaction that contributes to the inefficient insulin secretion

    Effect of Oral Iron Tablet Administration on Serum Feritin and Hemoglobin Concentration of Pre-pregnant Women with Mild Iron Deficiency Anemia in Bali

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    Iron deficiency anemia (IDA) is still to be a problem of pregnant women healthrelated to its high prevalence and its negative effects on health. Prevention efforts by ironsuplementation in pregnant woman have not reducing IDA problem in pregnant women yet. This failure is probably due to the assumption that IDA have been seen pre-pregnant. Totest this hypothesis, a quasi experimental study was conducted by randomized pre and posttest control group design. Sample were collected by multistage sampling random technicconsist of 47 women in treated group and 52 in control group. Both group were serumferritin and hemoglobin value test untill 3 time, pre-pregnant, early pregnant and duringpregnant. Iron tablet was administrated to treated group from the beginning of pre-pregnantperiod, continued until the first 3 months of pregnancy, while in control group iron tabletwas only given during the first 3 months of pregnancy. T-group result shown that meanserum ferritin and hemoglobin concentration at pregnant women on treated group(33,45±14,12 ?g/dL dan 12,25±1,20 g/dl) more high than control group (19,65±8,99 ?g/dLdan 10,91±0,67 g/dl), p<0,05. Mean difference serum ferritin and hemoglobinconcentration at pregnant women is 13,8 ?g/dL dan 1,34 g/dl (p<0,05). Benefid analysisresult shown that iron suplementation since pre-pregnant more benefid than ironsuplementation during pregnant (BCR >1). Based on these results, it can be concluded thatiron supplementation to IDA women starting from pre-pregnant period results in a bettereffect compare to oral iron supplementation during pregnancy only

    The Role of Mindfulness and Self Compassion Toward Depression Among Pregnant Women

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    Pregnant women tend to experience depression during pregnancy. This can affect mothers and babies' health widely. Previous research has found that mindfulness and self-compassion can reduce depression in pregnant women in abroad, but it still no specific research on it in Indonesia. Therefore, the purpose of this study was to see the relationship and also the role of mindfulness and self-compassion toward depression in pregnant women. Participants in this study were 121 pregnant women who lived in the area of Jakarta, Bogor, Depok, Tangerang, and Bekasi. This study used Five Facets of Mindfulness Questionnaire (FFMQ) to measure mindfulness, Self-Compassion Scale (SCS) to measure self-compassion, and Postnatal Depression Scale (EPDS) to measure depression in pregnant women. The results of this study showed that three dimensions of mindfulness (describing, acting with awareness, and non-judging) and self-compassion as a whole had a significant relationship with depression. Then the results of multiple regression tests conducted to get results that describing dimensions of mindfulness and self-compassion have a role to depression in pregnant women

    Factors that influence women\u27s disclosures of substance use during pregnancy : a qualitative study of ten midwives and ten pregnant women

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    The present study was designed to examine the factors that motivate or act as barriers to disclosure of substance use by pregnant women. Participants included 10 midwives and 10 pregnant women who attended two ante-natal clinics at an Australian maternity hospital. One clinic specialized in women who were substance users and one clinic was specifically for young women (under 19 years of age). Midwives and pregnant women were interviewed in-depth about disclosure of substance use. Interview transcripts were analyzed, and the results revealed six main themes: practice style, assessment of substance use, practice environment and privacy, child protection issues, health of the baby, and continuity of care. The findings are discussed in relation to recommendations for best practice in midwifery care when working with pregnant women who use substances.<br /

    Placental Morphology of Pregnant Iraqi Women with Rheumatic Heart Disease

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    Background: Placental morphology and cellular arrangement can be altered in maternal diseases. Rheumatic heart disease (RHD) is a chronic heart condition that can lead to death in pregnant women. The aim of this study is to determine the histological changes of the placenta in pregnant women suffering from RHD. Methods: Placentae were collected from 10 healthy pregnant women, and 31 pregnant women with heart conditions (26 with RHD and 5 with NRHD) who had been admitted to the Baghdad Teaching Hospital. Placental tissues were fixed in 10% formal-saline and were processed for light microscopy. Measurements including the placental weight and diameter of the chorionic villi capillaries were recorded. Results: The results indicate that there are many histological changes in pregnant women with RHD such as hyalinisation, fibrosis of the chorionic villi, proliferation of trophoblastic cells, and thickening of its membrane. Additionally, expectant mothers with RHD experience a reduction in capillary diameter and thickening of the capillary walls, and decreased size and weight of their placenta when compared with the control. Conclusions: Heart diseases, especially RHD, are associated with developmental damage of the placenta in pregnant women by injuring the endothelial cells of the placentas capillaries

    High mortality associated with an outbreak of hepatitis E among displaced persons in Darfur, Sudan

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    BACKGROUND: Hepatitis E virus (HEV) causes acute onset of jaundice and a high case-fatality ratio in pregnant women. We provide a clinical description of hospitalized case patients and assess the specific impact on pregnant women during a large epidemic of HEV infection in a displaced population in Mornay camp (78,800 inhabitants), western Darfur, Sudan. METHODS: We reviewed hospital records. A sample of 20 clinical cases underwent laboratory confirmation. These patients were tested for immunoglobulin G (IgG) and immunoglobulin M (IgM) antibody to HEV (serum) and for amplification of the HEV genome (serum and stool). We performed a cross-sectional survey in the community to determine the attack rate and case-fatality ratio in pregnant women. RESULTS: Over 6 months, 253 HEV cases were recorded at the hospital, of which 61 (24.1%) were in pregnant women. A total of 72 cases (39.1% of those for whom clinical records were available) had a diagnosis of hepatic encephalopathy. Of the 45 who died (case-fatality ratio, 17.8%), 19 were pregnant women (specific case-fatality ratio, 31.1%). Acute hepatitis E was confirmed in 95% (19/20) of cases sampled; 18 case-patients were positive for IgG (optical density ratio > or =3), for IgM (optical density ratio >2 ), or for both, whereas 1 was negative for IgG and IgM but positive for HEV RNA in serum. The survey identified 220 jaundiced women among the 1133 pregnant women recorded over 3 months (attack rate, 19.4%). A total of 18 deaths were recorded among these jaundiced pregnant women (specific case-fatality ratio, 8.2%). CONCLUSIONS: This large epidemic of HEV infection illustrates the dramatic impact of this disease on pregnant women. Timely interventions and a vaccine are urgently needed to prevent mortality in this special group

    Early Weight Gain During Pregnancy: Which Women Are the Most Affected?

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    Maternal weight gain during pregnancy is a good prediction tool in short and long term health of pregnant women and their children. To study the effect of early weight gain of pregnant women until the end of the 2nd trimester of pregnancy, depending on their pre-pregnancy body mass index. 116 healthy pregnant women were followed until the 2nd trimester of pregnancy, their weight and height before pregnancy, as well as the current weight at the end of the 1st and 2nd trimesters were collected. Data included age, parity, eating habits and physical activity level. Statistics were performed using the Statview software. The mean pre-pregnancy BMI was 27 ± 5.27 kg/m². Weight gain in the 2nd trimester is 6.33 ± 4.84 kg. It decreases with the increasing age of the mother (25% of women between 20 and 24.9 years vs 12.5% of more than 35). Also, it decreases with the increasing number of children (62.5% in nulliparous vs 25% in multiparous). Breakfast is skipped by 64.5 % of overweight pregnant women in the 1st trimester and 90 % in the 2nd one. 80.17% and 69.83% of pregnant women do not practice any physical activity. Overweight and obese pregnant women before pregnancy do not take enough weight during pregnancy. Prospects will to analyze behaviors related to health and social status
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