VLSI Design

This book provides some recent advances in design nanometer VLSI chips. The selected topics try to present some open problems and challenges with important topics ranging from design tools, new post-silicon devices, GPU-based parallel computing, emerging 3D integration, and antenna design. The book consists of two parts, with chapters such as: VLSI design for multi-sensor smart systems on a chip, Three-dimensional integrated circuits design for thousand-core processors, Parallel symbolic analysis of large analog circuits on GPU platforms, Algorithms for CAD tools VLSI design, A multilevel memetic algorithm for large SAT-encoded problems, etc

AI/ML Algorithms and Applications in VLSI Design and Technology

An evident challenge ahead for the integrated circuit (IC) industry in the nanometer regime is the investigation and development of methods that can reduce the design complexity ensuing from growing process variations and curtail the turnaround time of chip manufacturing. Conventional methodologies employed for such tasks are largely manual; thus, time-consuming and resource-intensive. In contrast, the unique learning strategies of artificial intelligence (AI) provide numerous exciting automated approaches for handling complex and data-intensive tasks in very-large-scale integration (VLSI) design and testing. Employing AI and machine learning (ML) algorithms in VLSI design and manufacturing reduces the time and effort for understanding and processing the data within and across different abstraction levels via automated learning algorithms. It, in turn, improves the IC yield and reduces the manufacturing turnaround time. This paper thoroughly reviews the AI/ML automated approaches introduced in the past towards VLSI design and manufacturing. Moreover, we discuss the scope of AI/ML applications in the future at various abstraction levels to revolutionize the field of VLSI design, aiming for high-speed, highly intelligent, and efficient implementations

Variability-Aware Circuit Performance Optimisation Through Digital Reconfiguration

This thesis proposes optimisation methods for improving the performance of circuits imple- mented on a custom reconfigurable hardware platform with knowledge of intrinsic variations, through the use of digital reconfiguration. With the continuing trend of transistor shrinking, stochastic variations become first order effects, posing a significant challenge for device reliability. Traditional device models tend to be too conservative, as the margins are greatly increased to account for these variations. Variation-aware optimisation methods are then required to reduce the performance spread caused by these substrate variations. The Programmable Analogue and Digital Array (PAnDA) is a reconfigurable hardware plat- form which combines the traditional architecture of a Field Programmable Gate Array (FPGA) with the concept of configurable transistor widths, and is used in this thesis as a platform on which variability-aware circuits can be implemented. A model of the PAnDA architecture is designed to allow for rapid prototyping of devices, making the study of the effects of intrinsic variability on circuit performance – which re- quires expensive statistical simulations – feasible. This is achieved by means of importing statistically-enhanced transistor performance data from RandomSPICE simulations into a model of the PAnDA architecture implemented in hardware. Digital reconfiguration is then used to explore the hardware resources available for performance optimisation. A bio-inspired optimisation algorithm is used to explore the large solution space more efficiently. Results from test circuits suggest that variation-aware optimisation can provide a significant reduction in the spread of the distribution of performance across various instances of circuits, as well as an increase in performance for each. Even if transistor geometry flexibility is not available, as is the case of traditional architectures, it is still possible to make use of the substrate variations to reduce spread and increase performance by means of function relocation

Unsupervised SFQ-Based Spiking Neural Network

Single Flux Quantum (SFQ) technology represents a groundbreaking advancement in computational efficiency and ultra-high-speed neuromorphic processing. The key features of SFQ technology, particularly data representation, transmission, and processing through SFQ pulses, closely mirror fundamental aspects of biological neural structures. Consequently, SFQ-based circuits emerge as an ideal candidate for realizing Spiking Neural Networks (SNNs). This study presents a proof-of-concept demonstration of an SFQ-based SNN architecture, showcasing its capacity for ultra-fast switching at remarkably low energy consumption per output activity. Notably, our work introduces innovative approaches: (i) We introduce a novel spike-timing-dependent plasticity mechanism to update synapses and to trace spike-activity by incorporating a leaky non-destructive readout circuit. (ii) We propose a novel method to dynamically regulate the threshold behavior of leaky integrate and fire superconductor neurons, enhancing the adaptability of our SNN architecture. (iii) Our research incorporates a novel winner-take-all mechanism, aligning with practical strategies for SNN development and enabling effective decision-making processes. The effectiveness of these proposed structural enhancements is evaluated by integrating high-level models into the BindsNET framework. By leveraging BindsNET, we model the online training of an SNN, integrating the novel structures into the learning process. To ensure the robustness and functionality of our circuits, we employ JoSIM for circuit parameter extraction and functional verification through simulation

Algorithmic techniques for physical design : macro placement and under-the-cell routing

With the increase of chip component density and new manufacturability constraints imposed by modern technology nodes, the role of algorithms for electronic design automation is key to the successful implementation of integrated circuits. Two of the critical steps in the physical design flows are macro placement and ensuring all design rules are honored after timing closure. This thesis proposes contributions to help in these stages, easing time-consuming manual steps and helping physical design engineers to obtain better layouts in reduced turnaround time. The first contribution is under-the-cell routing, a proposal to systematically connect standard cell components via lateral pins in the lower metal layers. The aim is to reduce congestion in the upper metal layers caused by extra metal and vias, decreasing the number of design rule violations. To allow cells to connect by abutment, a standard cell library is enriched with instances containing lateral pins in a pre-selected sharing track. Algorithms are proposed to maximize the numbers of connections via lateral connection by mapping placed cell instances to layouts with lateral pins, and proposing local placement modifications to increase the opportunities for such connections. Experimental results show a significant decrease in the number of pins, vias, and in number of design rule violations, with negligible impact on wirelength and timing. The second contribution, done in collaboration with eSilicon (a leading ASIC design company), is the creation of HiDaP, a macro placement tool for modern industrial designs. The proposed approach follows a multilevel scheme to floorplan hierarchical blocks, composed of macros and standard cells. By exploiting RTL information available in the netlist, the dataflow affinity between these blocks is modeled and minimized to find a macro placement with good wirelength and timing properties. The approach is further extended to allow additional engineer input, such as preferred macro locations, and also spectral and force methods to guide the floorplanning search. Experimental results show that the layouts generated by HiDaP outperforms those obtained by a state-of-the-art EDA physical design software, with similar wirelength and better timing when compared to manually designed tape-out ready macro placements. Layouts obtained by HiDaP have successfully been brought to near timing closure with one to two rounds of small modifications by physical design engineers. HiDaP has been fully integrated in the design flows of the company and its development remains an ongoing effort.A causa de l'increment de la densitat de components en els xip i les noves restriccions de disseny imposades pels últims nodes de fabricació, el rol de l'algorísmia en l'automatització del disseny electrònic ha esdevingut clau per poder implementar circuits integrats. Dos dels passos crucials en el procés de disseny físic és el placement de macros i assegurar la correcció de les regles de disseny un cop les restriccions de timing del circuit són satisfetes. Aquesta tesi proposa contribucions per ajudar en aquests dos reptes, facilitant laboriosos passos manuals en el procés i ajudant als enginyers de disseny físic a obtenir millors resultats en menys temps. La primera contribució és el routing "under-the-cell", una proposta per connectar cel·les estàndard usant pins laterals en les capes de metall inferior de manera sistemàtica. L'objectiu és reduir la congestió en les capes de metall superior causades per l'ús de metall i vies, i així disminuir el nombre de violacions de regles de disseny. Per permetre la connexió lateral de cel·les, estenem una llibreria de cel·les estàndard amb dissenys que incorporen connexions laterals. També proposem modificacions locals al placement per permetre explotar aquest tipus de connexions més sovint. Els resultats experimentals mostren una reducció significativa en el nombre de pins, vies i nombre de violacions de regles de disseny, amb un impacte negligible en wirelength i timing. La segona contribució, desenvolupada en col·laboració amb eSilicon (una empresa capdavantera en disseny ASIC), és el desenvolupament de HiDaP, una eina de macro placement per a dissenys industrials actuals. La proposta segueix un procés multinivell per fer el floorplan de blocks jeràrquics, formats per macros i cel·les estàndard. Mitjançant la informació RTL disponible en la netlist, l'afinitat de dataflow entre els mòduls es modela i minimitza per trobar macro placements amb bones propietats de wirelength i timing. La proposta també incorpora la possibilitat de rebre input addicional de l'enginyer, com ara suggeriments de les posicions de les macros. Finalment, també usa mètodes espectrals i de forçes per guiar la cerca de floorplans. Els resultats experimentals mostren que els dissenys generats amb HiDaP són millors que els obtinguts per eines comercials capdavanteres de EDA. Els resultats també mostren que els dissenys presentats poden obtenir un wirelength similar i millor timing que macro placements obtinguts manualment, usats per fabricació. Alguns dissenys obtinguts per HiDaP s'han dut fins a timing-closure en una o dues rondes de modificacions incrementals per part d'enginyers de disseny físic. L'eina s'ha integrat en el procés de disseny de eSilicon i el seu desenvolupament continua més enllà de les aportacions a aquesta tesi.Postprint (published version

Algorithmic techniques for physical design : macro placement and under-the-cell routing

With the increase of chip component density and new manufacturability constraints imposed by modern technology nodes, the role of algorithms for electronic design automation is key to the successful implementation of integrated circuits. Two of the critical steps in the physical design flows are macro placement and ensuring all design rules are honored after timing closure. This thesis proposes contributions to help in these stages, easing time-consuming manual steps and helping physical design engineers to obtain better layouts in reduced turnaround time. The first contribution is under-the-cell routing, a proposal to systematically connect standard cell components via lateral pins in the lower metal layers. The aim is to reduce congestion in the upper metal layers caused by extra metal and vias, decreasing the number of design rule violations. To allow cells to connect by abutment, a standard cell library is enriched with instances containing lateral pins in a pre-selected sharing track. Algorithms are proposed to maximize the numbers of connections via lateral connection by mapping placed cell instances to layouts with lateral pins, and proposing local placement modifications to increase the opportunities for such connections. Experimental results show a significant decrease in the number of pins, vias, and in number of design rule violations, with negligible impact on wirelength and timing. The second contribution, done in collaboration with eSilicon (a leading ASIC design company), is the creation of HiDaP, a macro placement tool for modern industrial designs. The proposed approach follows a multilevel scheme to floorplan hierarchical blocks, composed of macros and standard cells. By exploiting RTL information available in the netlist, the dataflow affinity between these blocks is modeled and minimized to find a macro placement with good wirelength and timing properties. The approach is further extended to allow additional engineer input, such as preferred macro locations, and also spectral and force methods to guide the floorplanning search. Experimental results show that the layouts generated by HiDaP outperforms those obtained by a state-of-the-art EDA physical design software, with similar wirelength and better timing when compared to manually designed tape-out ready macro placements. Layouts obtained by HiDaP have successfully been brought to near timing closure with one to two rounds of small modifications by physical design engineers. HiDaP has been fully integrated in the design flows of the company and its development remains an ongoing effort.A causa de l'increment de la densitat de components en els xip i les noves restriccions de disseny imposades pels últims nodes de fabricació, el rol de l'algorísmia en l'automatització del disseny electrònic ha esdevingut clau per poder implementar circuits integrats. Dos dels passos crucials en el procés de disseny físic és el placement de macros i assegurar la correcció de les regles de disseny un cop les restriccions de timing del circuit són satisfetes. Aquesta tesi proposa contribucions per ajudar en aquests dos reptes, facilitant laboriosos passos manuals en el procés i ajudant als enginyers de disseny físic a obtenir millors resultats en menys temps. La primera contribució és el routing "under-the-cell", una proposta per connectar cel·les estàndard usant pins laterals en les capes de metall inferior de manera sistemàtica. L'objectiu és reduir la congestió en les capes de metall superior causades per l'ús de metall i vies, i així disminuir el nombre de violacions de regles de disseny. Per permetre la connexió lateral de cel·les, estenem una llibreria de cel·les estàndard amb dissenys que incorporen connexions laterals. També proposem modificacions locals al placement per permetre explotar aquest tipus de connexions més sovint. Els resultats experimentals mostren una reducció significativa en el nombre de pins, vies i nombre de violacions de regles de disseny, amb un impacte negligible en wirelength i timing. La segona contribució, desenvolupada en col·laboració amb eSilicon (una empresa capdavantera en disseny ASIC), és el desenvolupament de HiDaP, una eina de macro placement per a dissenys industrials actuals. La proposta segueix un procés multinivell per fer el floorplan de blocks jeràrquics, formats per macros i cel·les estàndard. Mitjançant la informació RTL disponible en la netlist, l'afinitat de dataflow entre els mòduls es modela i minimitza per trobar macro placements amb bones propietats de wirelength i timing. La proposta també incorpora la possibilitat de rebre input addicional de l'enginyer, com ara suggeriments de les posicions de les macros. Finalment, també usa mètodes espectrals i de forçes per guiar la cerca de floorplans. Els resultats experimentals mostren que els dissenys generats amb HiDaP són millors que els obtinguts per eines comercials capdavanteres de EDA. Els resultats també mostren que els dissenys presentats poden obtenir un wirelength similar i millor timing que macro placements obtinguts manualment, usats per fabricació. Alguns dissenys obtinguts per HiDaP s'han dut fins a timing-closure en una o dues rondes de modificacions incrementals per part d'enginyers de disseny físic. L'eina s'ha integrat en el procés de disseny de eSilicon i el seu desenvolupament continua més enllà de les aportacions a aquesta tesi

Etude de l’expression des gènes nycthéméraux à la lumière de l’évolution

Circadian clocks are now an important part of the understanding of biological systems. They are ubiquitous, found in a wide range of biological processes, from molecular systems to behavior, and are also found almost everywhere in nature: in animals, plants, bacteria and fungi. This thesis focuses on biological systems that respond to factors oscillating on a 24-hour time scale. The detection of genes expressed with a periodicity of 24 hrs remains a complicated aspect of analytical work. We show that most detection methods are efficient only for strong signals and that outside of these genes, the algorithms seem to detect rhythmic genes in a rather random way. We have also tried to understand why genes have periodic variations in the amount of their RNA or their protein they encode. Indeed, 20% to 50% of cyclically accumulated proteins (i.e. nycthemeral) are translated from non-oscillating mRNAs, and conversely, there are many mRNAs that oscillate but not the proteins they encode. Why is that? My results suggest that the nycthemeral variation of proteins concerns on average highly expressed proteins, which remain on average costlier to produce for the cell (in terms of energy and molecular material) compared to other proteins produced in a non-rhythmic way. Moreover, these rhythmic proteins would be even more expensive to produce if the cell had to maintain constantly a sufficient high effective level of these proteins to ensure the function. The costs of protein production are large enough to be under natural selection, whereas the costs of mRNA production are not. So, why do cells periodically produce some mRNAs? My results suggest that the periodic oscillation in mRNA quantity concerns genes that have on average weaker cell-to-cell variability (noise) than genes with constant mRNA levels. Since causality is not very clear, it is still possible that the rhythmicity of mRNAs may optimize the expression precision for noise-sensitive functions over a period of time, repeatedly, every 24 hours. Finally, mRNA rhythmicity concerns genes that have undergone a strong purifying selection. This strong purifying selection does not seem to concern genes that have periodic protein levels, although there is insufficient data to really go further in the formulation of an evolutionary explanation. Overall, I suggest the hypothesis that rhythmicity of gene expression provides an adaptive advantage only to species living in highly changing environments (over 24 hours). In such environments, i.e. for a large part of marine and terrestrial ecosystems, it is possible that the rhythmicity of gene expression could have allowed the preservation of complex and costly new properties that would otherwise have been eliminated. The evolutionary trade-offs take into account the advantages provided by the function, its expression costs and precision required, but maybe also the variability of expression leading to phenotypic diversity improving adaptability in a fluctuating environment