A network approach for managing and processing big cancer data in clouds

Translational cancer research requires integrative analysis of multiple levels of big cancer data to identify and treat cancer. In order to address the issues that data is decentralised, growing and continually being updated, and the content living or archiving on different information sources partially overlaps creating redundancies as well as contradictions and inconsistencies, we develop a data network model and technology for constructing and managing big cancer data. To support our data network approach for data process and analysis, we employ a semantic content network approach and adopt the CELAR cloud platform. The prototype implementation shows that the CELAR cloud can satisfy the on-demanding needs of various data resources for management and process of big cancer data

Proactive cloud management for highly heterogeneous multi-cloud infrastructures

Various literature studies demonstrated that the cloud computing paradigm can help to improve availability and performance of applications subject to the problem of software anomalies. Indeed, the cloud resource provisioning model enables users to rapidly access new processing resources, even distributed over different geographical regions, that can be promptly used in the case of, e.g., crashes or hangs of running machines, as well as to balance the load in the case of overloaded machines. Nevertheless, managing a complex geographically-distributed cloud deploy could be a complex and time-consuming task. Autonomic Cloud Manager (ACM) Framework is an autonomic framework for supporting proactive management of applications deployed over multiple cloud regions. It uses machine learning models to predict failures of virtual machines and to proactively redirect the load to healthy machines/cloud regions. In this paper, we study different policies to perform efficient proactive load balancing across cloud regions in order to mitigate the effect of software anomalies. These policies use predictions about the mean time to failure of virtual machines. We consider the case of heterogeneous cloud regions, i.e regions with different amount of resources, and we provide an experimental assessment of these policies in the context of ACM Framework

Split and Migrate: Resource-Driven Placement and Discovery of Microservices at the Edge

Microservices architectures combine the use of fine-grained and independently-scalable services with lightweight communication protocols, such as REST calls over HTTP. Microservices bring flexibility to the development and deployment of application back-ends in the cloud. Applications such as collaborative editing tools require frequent interactions between the front-end running on users\u27 machines and a back-end formed of multiple microservices. User-perceived latencies depend on their connection to microservices, but also on the interaction patterns between these services and their databases. Placing services at the edge of the network, closer to the users, is necessary to reduce user-perceived latencies. It is however difficult to decide on the placement of complete stateful microservices at one specific core or edge location without trading between a latency reduction for some users and a latency increase for the others. We present how to dynamically deploy microservices on a combination of core and edge resources to systematically reduce user-perceived latencies. Our approach enables the split of stateful microservices, and the placement of the resulting splits on appropriate core and edge sites. Koala, a decentralized and resource-driven service discovery middleware, enables REST calls to reach and use the appropriate split, with only minimal changes to a legacy microservices application. Locality awareness using network coordinates further enables to automatically migrate services split and follow the location of the users. We confirm the effectiveness of our approach with a full prototype and an application to ShareLatex, a microservices-based collaborative editing application