Cancer diagnosis using deep learning: A bibliographic review

In this paper, we first describe the basics of the field of cancer diagnosis, which includes steps of cancer diagnosis followed by the typical classification methods used by doctors, providing a historical idea of cancer classification techniques to the readers. These methods include Asymmetry, Border, Color and Diameter (ABCD) method, seven-point detection method, Menzies method, and pattern analysis. They are used regularly by doctors for cancer diagnosis, although they are not considered very efficient for obtaining better performance. Moreover, considering all types of audience, the basic evaluation criteria are also discussed. The criteria include the receiver operating characteristic curve (ROC curve), Area under the ROC curve (AUC), F1 score, accuracy, specificity, sensitivity, precision, dice-coefficient, average accuracy, and Jaccard index. Previously used methods are considered inefficient, asking for better and smarter methods for cancer diagnosis. Artificial intelligence and cancer diagnosis are gaining attention as a way to define better diagnostic tools. In particular, deep neural networks can be successfully used for intelligent image analysis. The basic framework of how this machine learning works on medical imaging is provided in this study, i.e., pre-processing, image segmentation and post-processing. The second part of this manuscript describes the different deep learning techniques, such as convolutional neural networks (CNNs), generative adversarial models (GANs), deep autoencoders (DANs), restricted Boltzmann’s machine (RBM), stacked autoencoders (SAE), convolutional autoencoders (CAE), recurrent neural networks (RNNs), long short-term memory (LTSM), multi-scale convolutional neural network (M-CNN), multi-instance learning convolutional neural network (MIL-CNN). For each technique, we provide Python codes, to allow interested readers to experiment with the cited algorithms on their own diagnostic problems. The third part of this manuscript compiles the successfully applied deep learning models for different types of cancers. Considering the length of the manuscript, we restrict ourselves to the discussion of breast cancer, lung cancer, brain cancer, and skin cancer. The purpose of this bibliographic review is to provide researchers opting to work in implementing deep learning and artificial neural networks for cancer diagnosis a knowledge from scratch of the state-of-the-art achievements

A Novel Sep-Unet Architecture of Convolutional Neural Networks to Improve Dermoscopic Image Segmentation by Training Parameters Reduction

Nowadays, we use dermoscopic images as one of the imaging methods in diagnosis of skin lesions such as skin cancer. But due to the noise and other problems, including hair artifacts around the lesion, this issue requires automatic and reliable segmentation methods. The diversity in the color and structure of the skin lesions is a challenging reason for automatic skin lesion segmentation. In this study, we used convolutional neural networks (CNN) as an efficient method for dermoscopic image segmentation. The main goal of this research is to recommend a novel architecture of deep neural networks for the injured lesion in dermoscopic images which has been improved by the convolutional layers based on the separable layers. By convolutional layers and the specific operations on the kernel of them, the velocity of the algorithm increases and the training parameters decrease. Additionally, we used a suitable preprocessing method to enter the images into the neural network. Suitable structure of the convolutional layers, separable convolutional layers and transposed convolution in the down sampling and up sampling parts, have made the structure of the mentioned neural network. This algorithm is named Sep-unet and could segment the images with 98% dice coefficient