21,614 research outputs found
Computer Aided ECG Analysis - State of the Art and Upcoming Challenges
In this paper we present current achievements in computer aided ECG analysis
and their applicability in real world medical diagnosis process. Most of the
current work is covering problems of removing noise, detecting heartbeats and
rhythm-based analysis. There are some advancements in particular ECG segments
detection and beat classifications but with limited evaluations and without
clinical approvals. This paper presents state of the art advancements in those
areas till present day. Besides this short computer science and signal
processing literature review, paper covers future challenges regarding the ECG
signal morphology analysis deriving from the medical literature review. Paper
is concluded with identified gaps in current advancements and testing, upcoming
challenges for future research and a bullseye test is suggested for morphology
analysis evaluation.Comment: 7 pages, 3 figures, IEEE EUROCON 2013 International conference on
computer as a tool, 1-4 July 2013, Zagreb, Croati
Healthcare Robotics
Robots have the potential to be a game changer in healthcare: improving
health and well-being, filling care gaps, supporting care givers, and aiding
health care workers. However, before robots are able to be widely deployed, it
is crucial that both the research and industrial communities work together to
establish a strong evidence-base for healthcare robotics, and surmount likely
adoption barriers. This article presents a broad contextualization of robots in
healthcare by identifying key stakeholders, care settings, and tasks; reviewing
recent advances in healthcare robotics; and outlining major challenges and
opportunities to their adoption.Comment: 8 pages, Communications of the ACM, 201
Synthetic Biology: A Bridge between Artificial and Natural Cells.
Artificial cells are simple cell-like entities that possess certain properties of natural cells. In general, artificial cells are constructed using three parts: (1) biological membranes that serve as protective barriers, while allowing communication between the cells and the environment; (2) transcription and translation machinery that synthesize proteins based on genetic sequences; and (3) genetic modules that control the dynamics of the whole cell. Artificial cells are minimal and well-defined systems that can be more easily engineered and controlled when compared to natural cells. Artificial cells can be used as biomimetic systems to study and understand natural dynamics of cells with minimal interference from cellular complexity. However, there remain significant gaps between artificial and natural cells. How much information can we encode into artificial cells? What is the minimal number of factors that are necessary to achieve robust functioning of artificial cells? Can artificial cells communicate with their environments efficiently? Can artificial cells replicate, divide or even evolve? Here, we review synthetic biological methods that could shrink the gaps between artificial and natural cells. The closure of these gaps will lead to advancement in synthetic biology, cellular biology and biomedical applications
Constructing living buildings: a review of relevant technologies for a novel application of biohybrid robotics
Biohybrid robotics takes an engineering approach to the expansion and exploitation of biological behaviours for application to automated tasks. Here, we identify the construction of living buildings and infrastructure as a high-potential application domain for biohybrid robotics, and review technological advances relevant to its future development. Construction, civil infrastructure maintenance and building occupancy in the last decades have comprised a major portion of economic production, energy consumption and carbon emissions. Integrating biological organisms into automated construction tasks and permanent building components therefore has high potential for impact. Live materials can provide several advantages over standard synthetic construction materials, including self-repair of damage, increase rather than degradation of structural performance over time, resilience to corrosive environments, support of biodiversity, and mitigation of urban heat islands. Here, we review relevant technologies, which are currently disparate. They span robotics, self-organizing systems, artificial life, construction automation, structural engineering, architecture, bioengineering, biomaterials, and molecular and cellular biology. In these disciplines, developments relevant to biohybrid construction and living buildings are in the early stages, and typically are not exchanged between disciplines. We, therefore, consider this review useful to the future development of biohybrid engineering for this highly interdisciplinary application.publishe
Computational challenges of systems biology
Progress in the study of biological systems such as the heart, brain, and liver will require computer scientists to work closely with life scientists and mathematicians. Computer science will play a key role in shaping the new discipline of systems biology and addressing the significant computational challenges it poses
Detecting event-related recurrences by symbolic analysis: Applications to human language processing
Quasistationarity is ubiquitous in complex dynamical systems. In brain
dynamics there is ample evidence that event-related potentials reflect such
quasistationary states. In order to detect them from time series, several
segmentation techniques have been proposed. In this study we elaborate a recent
approach for detecting quasistationary states as recurrence domains by means of
recurrence analysis and subsequent symbolisation methods. As a result,
recurrence domains are obtained as partition cells that can be further aligned
and unified for different realisations. We address two pertinent problems of
contemporary recurrence analysis and present possible solutions for them.Comment: 24 pages, 6 figures. Draft version to appear in Proc Royal Soc
Behaviour-based Knowledge Systems: An Epigenetic Path from Behaviour to Knowledge
In this paper we expose the theoretical background underlying our current research.
This consists in the development of behaviour-based knowledge systems, for closing
the gaps between behaviour-based and knowledge-based systems, and also
between the understandings of the phenomena they model. We expose the
requirements and stages for developing behaviour-based knowledge systems and
discuss their limits. We believe that these are necessary conditions for the
development of higher order cognitive capacities, in artificial and natural cognitive
systems
Extracorporeal membrane oxygenation simulation-based training: methods, drawbacks and a novel solution
Introduction: Patients under the error-prone and complication-burdened extracorporeal membrane oxygenation (ECMO) are looked after by a highly trained, multidisciplinary team. Simulation-based training (SBT) affords ECMO centers the opportunity to equip practitioners with the technical dexterity required to manage emergencies. The aim of this article is to review ECMO SBT activities and technology followed by a novel solution to current challenges. ECMO simulation: The commonly-used simulation approach is easy-to-build as it requires a functioning ECMO machine and an altered circuit. Complications are simulated through manual circuit manipulations. However, scenario diversity is limited and often lacks physiological and/or mechanical authenticity. It is also expensive to continuously operate due to the consumption of highly specialized equipment. Technological aid: Commercial extensions can be added to enable remote control and to automate circuit manipulation, but do not improve on the realism or cost-effectiveness. A modular ECMO simulator: To address those drawbacks, we are developing a standalone modular ECMO simulator that employs affordable technology for high-fidelity simulation.Peer reviewe
- …