48,167 research outputs found
Self-supervised pseudo-colorizing of masked cells
Self-supervised learning, which is strikingly referred to as the dark matter of intelligence, is gaining more attention in biomedical applications of deep learning. In this work, we introduce a novel self-supervision objective for the analysis of cells in biomedical microscopy images. We propose training deep learning models to pseudo-colorize masked cells. We use a physics-informed pseudo-spectral colormap that is well suited for colorizing cell topology. Our experiments reveal that approximating semantic segmentation by pseudo-colorization is beneficial for subsequent fine-tuning on cell detection. Inspired by the recent success of masked image modeling, we additionally mask out cell parts and train to reconstruct these parts to further enrich the learned representations. We compare our pre-training method with self-supervised frameworks including contrastive learning (SimCLR), masked autoencoders (MAEs), and edge-based self-supervision. We build upon our previous work and train hybrid models for cell detection, which contain both convolutional and vision transformer modules. Our pre-training method can outperform SimCLR, MAE-like masked image modeling, and edge-based self-supervision when pre-training on a diverse set of six fluorescence microscopy datasets. Code is available at: https://github.com/roydenwa/pseudo-colorize-masked-cells
Self-supervised pseudo-colorizing of masked cells
Self-supervised learning, which is strikingly referred to as the dark matter of intelligence, is gaining more attention in biomedical applications of deep learning. In this work, we introduce a novel self-supervision objective for the analysis of cells in biomedical microscopy images. We propose training deep learning models to pseudo-colorize masked cells. We use a physics-informed pseudo-spectral colormap that is well suited for colorizing cell topology. Our experiments reveal that approximating semantic segmentation by pseudo-colorization is beneficial for subsequent fine-tuning on cell detection. Inspired by the recent success of masked image modeling, we additionally mask out cell parts and train to reconstruct these parts to further enrich the learned representations. We compare our pre-training method with self-supervised frameworks including contrastive learning (SimCLR), masked autoencoders (MAEs), and edge-based self-supervision. We build upon our previous work and train hybrid models for cell detection, which contain both convolutional and vision transformer modules. Our pre-training method can outperform SimCLR, MAE-like masked image modeling, and edge-based self-supervision when pre-training on a diverse set of six fluorescence microscopy datasets. Code is available at: https://github.com/roydenwa/pseudo-colorize-masked-cell
Physics Inspired Optimization on Semantic Transfer Features: An Alternative Method for Room Layout Estimation
In this paper, we propose an alternative method to estimate room layouts of
cluttered indoor scenes. This method enjoys the benefits of two novel
techniques. The first one is semantic transfer (ST), which is: (1) a
formulation to integrate the relationship between scene clutter and room layout
into convolutional neural networks; (2) an architecture that can be end-to-end
trained; (3) a practical strategy to initialize weights for very deep networks
under unbalanced training data distribution. ST allows us to extract highly
robust features under various circumstances, and in order to address the
computation redundance hidden in these features we develop a principled and
efficient inference scheme named physics inspired optimization (PIO). PIO's
basic idea is to formulate some phenomena observed in ST features into
mechanics concepts. Evaluations on public datasets LSUN and Hedau show that the
proposed method is more accurate than state-of-the-art methods.Comment: To appear in CVPR 2017. Project Page:
https://sites.google.com/view/st-pio
Towards a bio-inspired mixed-signal retinal processor
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A biologically inspired spiking model of visual processing for image feature detection
To enable fast reliable feature matching or tracking in scenes, features need to be discrete and meaningful, and hence edge or corner features, commonly called interest points are often used for this purpose. Experimental research has illustrated that biological vision systems use neuronal circuits to extract particular features such as edges or corners from visual scenes. Inspired by this biological behaviour, this paper proposes a biologically inspired spiking neural network for the purpose of image feature extraction. Standard digital images are processed and converted to spikes in a manner similar to the processing that transforms light into spikes in the retina. Using a hierarchical spiking network, various types of biologically inspired receptive fields are used to extract progressively complex image features. The performance of the network is assessed by examining the repeatability of extracted features with visual results presented using both synthetic and real images
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