Service-oriented architecture for ontologies supporting multi-agent system negotiations in virtual enterprise

This paper offers a service-oriented architecture (SOA) for ontology-based multi-agent system (MAS) negotiations in the context of virtual enterprises (VEs). The objective of this paper is fourfold. First, it is to design a SOA which utilizes ontology and MAS to provide a distributed and interoperable environment for automated negotiations in VE. In this architecture, individual ontologies for both the VE initiator and its potential partners are constructed to describe and store resources and service knowledge. Second, a series of semantic ontology matching methods are developed to reach agents' interoperability during the negotiation process. Third, correspondence-based extended contract net protocol is presented, which provides basic guidelines for agents' reaching mutual understandings and service negotiation. Last, a fuzzy set theory based knowledge reuse approach is proposed to evaluate the current negotiation behaviors of the VE partners. A walkthrough example is presented to illustrate the methodologies and system architecture proposed in this paper. © 2010 The Author(s).published_or_final_versionSpringer Open Choice, 21 Feb 201

A Hybrid Simulation Framework of Consumer-to-Consumer Ecommerce Space

In the past decade, ecommerce transformed the business models of many organizations. Information Technology leveled the playing field for new participants, who were capable of causing disruptive changes in every industry. Web 2.0 or Social Web further redefined ways users enlist for services. It is now easy to be influenced to make choices of services based on recommendations of friends and popularity amongst peers. This research proposes a simulation framework to investigate how actions of stakeholders at this level of complexity affect system performance as well as the dynamics that exist between different models using concepts from the fields of operations engineering, engineering management, and multi-model simulation. Viewing this complex model from a systems perspective calls for the integration of different levels of behaviors. Complex interactions exist among stakeholders, the environment and available technology. The presence of continuous and discrete behaviors coupled with stochastic and deterministic behaviors present challenges for using standalone simulation tools to simulate the business model. We propose a framework that takes into account dynamic system complexity and risk from a hybrid paradigm. The SCOR model is employed to map the business processes and it is implemented using agent based simulation and system dynamics. By combining system dynamics at the strategy level with agent based models of consumer behaviors, an accurate yet efficient representation of the business model that makes for sound basis of decision making can be achieved to maximize stakeholders\u27 utility

Coordination Issues in Complex Socio-technical Systems: Self-organisation of Knowledge in MoK

The thesis proposes the Molecules of Knowledge (MoK) model for self-organisation of knowledge in knowledge-intensive socio-technical systems. The main contribution is the conception, definition, design, and implementation of the MoK model. The model is based on a chemical metaphor for self-organising coordination, in which coordination laws are interpreted as artificial chemical reactions ruling evolution of the molecules of knowledge living in the system (the information chunks), indirectly coordinating the users working with them. In turn, users may implicitly affect system behaviour with their interactions, according to the cognitive theory of behavioural implicit communication, integrated in MoK. The theory states that any interaction conveys tacit messages that can be suitably interpreted by the coordination model to better support users' workflows. Design and implementation of the MoK model required two other contributions: conception, design, and tuning of the artificial chemical reactions with custom kinetic rates, playing the role of the coordination laws, and development of an infrastructure supporting situated coordination, both in time, space, and w.r.t. the environment, along with a dedicated coordination language

The Shaping of Cancer by the Tumour Microenvironment and Its Relevance for Cancer Therapy

In this book, we present a compilation of original research articles as well as review articles that are focused on improving our understanding of the molecular and cellular mechanisms by which cancer cells adapt to their microenvironment. These include the interplay between cancer cells and the surrounding microenvironmental cells (e.g., macrophages, tumor-infiltrating lymphocytes and myeloid cells) and microenvironmental environments (e.g., oxidative stress, pH, hypoxia) and the implications of this dynamic interaction to tumor radioresistance, chemoresistance, invasion and metastasis. Finally, the importance and relevance of these findings are translated to cancer therapy