LiveSketch: Query Perturbations for Guided Sketch-based Visual Search

LiveSketch is a novel algorithm for searching large image collections using hand-sketched queries. LiveSketch tackles the inherent ambiguity of sketch search by creating visual suggestions that augment the query as it is drawn, making query specification an iterative rather than one-shot process that helps disambiguate users' search intent. Our technical contributions are: a triplet convnet architecture that incorporates an RNN based variational autoencoder to search for images using vector (stroke-based) queries; real-time clustering to identify likely search intents (and so, targets within the search embedding); and the use of backpropagation from those targets to perturb the input stroke sequence, so suggesting alterations to the query in order to guide the search. We show improvements in accuracy and time-to-task over contemporary baselines using a 67M image corpus.Comment: Accepted to CVPR 201

Predicting Genetic Regulatory Response Using Classification

We present a novel classification-based method for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple organisms such as Saccharomyces cerevisiae, we can learn a decision rule for predicting whether a gene is up- or down-regulated in a particular experiment based on (1) the presence of binding site subsequences (``motifs'') in the gene's regulatory region and (2) the expression levels of regulators such as transcription factors in the experiment (``parents''). Thus our learning task integrates two qualitatively different data sources: genome-wide cDNA microarray data across multiple perturbation and mutant experiments along with motif profile data from regulatory sequences. We convert the regression task of predicting real-valued gene expression measurement to a classification task of predicting +1 and -1 labels, corresponding to up- and down-regulation beyond the levels of biological and measurement noise in microarray measurements. The learning algorithm employed is boosting with a margin-based generalization of decision trees, alternating decision trees. This large-margin classifier is sufficiently flexible to allow complex logical functions, yet sufficiently simple to give insight into the combinatorial mechanisms of gene regulation. We observe encouraging prediction accuracy on experiments based on the Gasch S. cerevisiae dataset, and we show that we can accurately predict up- and down-regulation on held-out experiments. Our method thus provides predictive hypotheses, suggests biological experiments, and provides interpretable insight into the structure of genetic regulatory networks.Comment: 8 pages, 4 figures, presented at Twelfth International Conference on Intelligent Systems for Molecular Biology (ISMB 2004), supplemental website: http://www.cs.columbia.edu/compbio/geneclas

Online Metric-Weighted Linear Representations for Robust Visual Tracking

In this paper, we propose a visual tracker based on a metric-weighted linear representation of appearance. In order to capture the interdependence of different feature dimensions, we develop two online distance metric learning methods using proximity comparison information and structured output learning. The learned metric is then incorporated into a linear representation of appearance. We show that online distance metric learning significantly improves the robustness of the tracker, especially on those sequences exhibiting drastic appearance changes. In order to bound growth in the number of training samples, we design a time-weighted reservoir sampling method. Moreover, we enable our tracker to automatically perform object identification during the process of object tracking, by introducing a collection of static template samples belonging to several object classes of interest. Object identification results for an entire video sequence are achieved by systematically combining the tracking information and visual recognition at each frame. Experimental results on challenging video sequences demonstrate the effectiveness of the method for both inter-frame tracking and object identification.Comment: 51 pages. Appearing in IEEE Transactions on Pattern Analysis and Machine Intelligenc