KindMed: Knowledge-Induced Medicine Prescribing Network for Medication Recommendation

Extensive adoption of electronic health records (EHRs) offers opportunities for its use in various clinical analyses. We could acquire more comprehensive insights by enriching an EHR cohort with external knowledge (e.g., standardized medical ontology and wealthy semantics curated on the web) as it divulges a spectrum of informative relations between observed medical codes. This paper proposes a novel Knowledge-Induced Medicine Prescribing Network (KindMed) framework to recommend medicines by inducing knowledge from myriad medical-related external sources upon the EHR cohort, rendering them as medical knowledge graphs (KGs). On top of relation-aware graph representation learning to unravel an adequate embedding of such KGs, we leverage hierarchical sequence learning to discover and fuse clinical and medicine temporal dynamics across patients' historical admissions for encouraging personalized recommendations. In predicting safe, precise, and personalized medicines, we devise an attentive prescribing that accounts for and associates three essential aspects, i.e., a summary of joint historical medical records, clinical condition progression, and the current clinical state of patients. We exhibited the effectiveness of our KindMed on the augmented real-world EHR cohorts, etching leading performances against graph-driven competing baselines

StratMed: Relevance Stratification for Low-resource Medication Recommendation

With the growing imbalance between limited medical resources and escalating demands, AI-based clinical tasks have become paramount. Medication recommendation, as a sub-domain, aims to amalgamate longitudinal patient history with medical knowledge, assisting physicians in prescribing safer and more accurate medication combinations. Existing methods overlook the inherent long-tail distribution in medical data, lacking balanced representation between head and tail data, which leads to sub-optimal model performance. To address this challenge, we introduce StratMed, a model that incorporates an innovative relevance stratification mechanism. It harmonizes discrepancies in data long-tail distribution and strikes a balance between the safety and accuracy of medication combinations. Specifically, we first construct a pre-training method using deep learning networks to obtain entity representation. After that, we design a pyramid-like data stratification method to obtain more generalized entity relationships by reinforcing the features of unpopular entities. Based on this relationship, we designed two graph structures to express medication precision and safety at the same level to obtain visit representations. Finally, the patient's historical clinical information is fitted to generate medication combinations for the current health condition. Experiments on the MIMIC-III dataset demonstrate that our method has outperformed current state-of-the-art methods in four evaluation metrics (including safety and accuracy)

Social Search: retrieving information in Online Social Platforms -- A Survey

Social Search research deals with studying methodologies exploiting social information to better satisfy user information needs in Online Social Media while simplifying the search effort and consequently reducing the time spent and the computational resources utilized. Starting from previous studies, in this work, we analyze the current state of the art of the Social Search area, proposing a new taxonomy and highlighting current limitations and open research directions. We divide the Social Search area into three subcategories, where the social aspect plays a pivotal role: Social Question&Answering, Social Content Search, and Social Collaborative Search. For each subcategory, we present the key concepts and selected representative approaches in the literature in greater detail. We found that, up to now, a large body of studies model users' preferences and their relations by simply combining social features made available by social platforms. It paves the way for significant research to exploit more structured information about users' social profiles and behaviors (as they can be inferred from data available on social platforms) to optimize their information needs further

Report on the SIGIR 2013 Workshop on Health Search and Discovery

Abstract The workshop brought together 40 researchers and practitioners from academia and industry to discuss search and discovery in the medical domain. Presentations and discussions spanned several challenging and important topics, including directions improving the accessibility of medical and health information for lay people (with associated enhancements to result ranking algorithms and search interfaces), and methods for discovering biomedical phenomena from the information that people seek online, as evidenced in query streams and other sources such as social and news media. A thread throughout the workshop was the opportunity for new methods and applications to enhance the quality of life of people suffering from medical disorders, carry out surveillance of emerging diseases and other threats, and, more generally, to improve the health and well-being of people via tools to support their health-related information behavior

Deliverable D4.1 Specification of user profiling and contextualisation

This deliverable presents a comprehensive research of past work in the field of capturing and interpreting user preferences and context and an overview of relevant digital media-specific techniques, aiming to provide insights and ideas for innovative context-aware user preference learning and to justify the user modelling strategies considered within LinkedTV’s WP4. Based on this research and a study over the specific technical and conceptual requirements of LinkedTV, a prototypical design for profiling and contextualizing user needs in a linked media environment is specified

Congenial Web Search : A Conceptual Framework for Personalized, Collaborative, and Social Peer-to-Peer Retrieval

Traditional information retrieval methods fail to address the fact that information consumption and production are social activities. Most Web search engines do not consider the social-cultural environment of users' information needs and the collaboration between users. This dissertation addresses a new search paradigm for Web information retrieval denoted as Congenial Web Search. It emphasizes personalization, collaboration, and socialization methods in order to improve effectiveness. The client-server architecture of Web search engines only allows the consumption of information. A peer-to-peer system architecture has been developed in this research to improve information seeking. Each user is involved in an interactive process to produce meta-information. Based on a personalization strategy on each peer, the user is supported to give explicit feedback for relevant documents. His information need is expressed by a query that is stored in a Peer Search Memory. On one hand, query-document associations are incorporated in a personalized ranking method for repeated information needs. The performance is shown in a known-item retrieval setting. On the other hand, explicit feedback of each user is useful to discover collaborative information needs. A new method for a controlled grouping of query terms, links, and users was developed to maintain Virtual Knowledge Communities. The quality of this grouping represents the effectiveness of grouped terms and links. Both strategies, personalization and collaboration, tackle the problem of a missing socialization among searchers. Finally, a concept for integrated information seeking was developed. This incorporates an integrated representation to improve effectiveness of information retrieval and information filtering. An integrated information retrieval process explores a virtual search network of Peer Search Memories in order to accomplish a reputation-based ranking. In addition, the community structure is considered by an integrated information filtering process. Both concepts have been evaluated and shown to have a better performance than traditional techniques. The methods presented in this dissertation offer the potential towards more transparency, and control of Web search