18 research outputs found
A Comprehensive Review of Techniques for Processing and Analyzing Fetal Heart Rate Signals
The availability of standardized guidelines regarding the use of electronic fetal monitoring
(EFM) in clinical practice has not effectively helped to solve the main drawbacks of fetal heart rate
(FHR) surveillance methodology, which still presents inter- and intra-observer variability as well
as uncertainty in the classification of unreassuring or risky FHR recordings. Given the clinical
relevance of the interpretation of FHR traces as well as the role of FHR as a marker of fetal wellbeing
autonomous nervous system development, many different approaches for computerized processing
and analysis of FHR patterns have been proposed in the literature. The objective of this review is to
describe the techniques, methodologies, and algorithms proposed in this field so far, reporting their
main achievements and discussing the value they brought to the scientific and clinical community.
The review explores the following two main approaches to the processing and analysis of FHR
signals: traditional (or linear) methodologies, namely, time and frequency domain analysis, and less
conventional (or nonlinear) techniques. In this scenario, the emerging role and the opportunities
offered by Artificial Intelligence tools, representing the future direction of EFM, are also discussed
with a specific focus on the use of Artificial Neural Networks, whose application to the analysis of
accelerations in FHR signals is also examined in a case study conducted by the authors
Permutation entropy and its main biomedical and econophysics applications: a review
Entropy is a powerful tool for the analysis of time series, as it allows describing the probability distributions of the possible state of a system, and therefore the information encoded in it. Nevertheless, important information may be codified also in the temporal dynamics, an aspect which is not usually taken into account. The idea of calculating entropy based on permutation patterns (that is, permutations defined by the order relations among values of a time series) has received a lot of attention in the last years, especially for the understanding of complex and chaotic systems. Permutation entropy directly accounts for the temporal information contained in the time series; furthermore, it has the quality of simplicity, robustness and very low computational cost. To celebrate the tenth anniversary of the original work, here we analyze the theoretical foundations of the permutation entropy, as well as the main recent applications to the analysis of economical markets and to the understanding of biomedical systems.Facultad de IngenierÃ
Persistent Homology of Coarse Grained State Space Networks
This work is dedicated to the topological analysis of complex transitional
networks for dynamic state detection. Transitional networks are formed from
time series data and they leverage graph theory tools to reveal information
about the underlying dynamic system. However, traditional tools can fail to
summarize the complex topology present in such graphs. In this work, we
leverage persistent homology from topological data analysis to study the
structure of these networks. We contrast dynamic state detection from time
series using CGSSN and TDA to two state of the art approaches: Ordinal
Partition Networks (OPNs) combined with TDA, and the standard application of
persistent homology to the time-delay embedding of the signal. We show that the
CGSSN captures rich information about the dynamic state of the underlying
dynamical system as evidenced by a significant improvement in dynamic state
detection and noise robustness in comparison to OPNs. We also show that because
the computational time of CGSSN is not linearly dependent on the signal's
length, it is more computationally efficient than applying TDA to the
time-delay embedding of the time series
Review and classification of variability analysis techniques with clinical applications
Analysis of patterns of variation of time-series, termed variability analysis, represents a rapidly evolving discipline with increasing applications in different fields of science. In medicine and in particular critical care, efforts have focussed on evaluating the clinical utility of variability. However, the growth and complexity of techniques applicable to this field have made interpretation and understanding of variability more challenging. Our objective is to provide an updated review of variability analysis techniques suitable for clinical applications. We review more than 70 variability techniques, providing for each technique a brief description of the underlying theory and assumptions, together with a summary of clinical applications. We propose a revised classification for the domains of variability techniques, which include statistical, geometric, energetic, informational, and invariant. We discuss the process of calculation, often necessitating a mathematical transform of the time-series. Our aims are to summarize a broad literature, promote a shared vocabulary that would improve the exchange of ideas, and the analyses of the results between different studies. We conclude with challenges for the evolving science of variability analysis