An Iterative Adaptive Approach for Blood Velocity Estimation Using Ultrasound

Publication in the conference proceedings of EUSIPCO, Aalborg, Denmark, 201

Computationally Efficient Time-Recursive IAA-Based Blood Velocity Estimation

High-resolution spectral Doppler is an important and pow- erful non-invasive tool for estimation of velocities in blood vessels using medical ultrasound scanners. Such estimates are typically formed using an averaged periodogram technique, resulting in well-known limitations in the resulting spectral resolution. Recently, we have proposed tech- niques to instead form high-resolution data-adaptive estimates exploiting measurements along both depth and emission. The resulting estimates gives noticeably superior velocity estimates as compared to the standard technique, but suffers from a high computational complexity, making it interesting to formulate computationally efficient implementations of the estimators. In this work, by exploiting the rich structure of the iterative adaptive approach (IAA) based estimator, we examine how these estimates can be efficiently implemented in a time-recursive manner using both exact and approximate formulations of the method. The resulting algorithms are shown to reduce the necessary computational load with several orders of magnitude without noticeable loss of performance

Annual report 2015

Accessions considered in the study. Overview of the material considered in this study. For all materials, the GenBank identifier, the accession and species name as used in this study (Species) as well as their species synonyms used in the donor seed banks or in the NCBI GenBank (Material source/Reference) are provided. The genome symbol, and the country of origin, where the material was originally collected are given. The ploidy level measured in the scope of this study and the information if a herbarium voucher could be deposited in the herbarium of IPK Gatersleben (GAT) is given. Genomic formulas of tetraploids and hexploids are given as “female x male parent”. The genomes of Aegilops taxa follow Kilian et al. [74] and Li et al. [84]. Genome denominations for Hordeum follow Blattner [107] and Bernhardt [12] for the remaining taxa. (XLS 84 kb

Psr1p interacts with SUN/sad1p and EB1/mal3p to establish the bipolar spindle

Regular Abstracts - Sunday Poster Presentations: no. 382During mitosis, interpolar microtubules from two spindle pole bodies (SPBs) interdigitate to create an antiparallel microtubule array for accommodating numerous regulatory proteins. Among these proteins, the kinesin-5 cut7p/Eg5 is the key player responsible for sliding apart antiparallel microtubules and thus helps in establishing the bipolar spindle. At the onset of mitosis, two SPBs are adjacent to one another with most microtubules running nearly parallel toward the nuclear envelope, creating an unfavorable microtubule configuration for the kinesin-5 kinesins. Therefore, how the cell organizes the antiparallel microtubule array in the first place at mitotic onset remains enigmatic. Here, we show that a novel protein psrp1p localizes to the SPB and plays a key role in organizing the antiparallel microtubule array. The absence of psr1+ leads to a transient monopolar spindle and massive chromosome loss. Further functional characterization demonstrates that psr1p is recruited to the SPB through interaction with the conserved SUN protein sad1p and that psr1p physically interacts with the conserved microtubule plus tip protein mal3p/EB1. These results suggest a model that psr1p serves as a linking protein between sad1p/SUN and mal3p/EB1 to allow microtubule plus ends to be coupled to the SPBs for organization of an antiparallel microtubule array. Thus, we conclude that psr1p is involved in organizing the antiparallel microtubule array in the first place at mitosis onset by interaction with SUN/sad1p and EB1/mal3p, thereby establishing the bipolar spindle.postprin