Ontology of core data mining entities

In this article, we present OntoDM-core, an ontology of core data mining entities. OntoDM-core defines themost essential datamining entities in a three-layered ontological structure comprising of a specification, an implementation and an application layer. It provides a representational framework for the description of mining structured data, and in addition provides taxonomies of datasets, data mining tasks, generalizations, data mining algorithms and constraints, based on the type of data. OntoDM-core is designed to support a wide range of applications/use cases, such as semantic annotation of data mining algorithms, datasets and results; annotation of QSAR studies in the context of drug discovery investigations; and disambiguation of terms in text mining. The ontology has been thoroughly assessed following the practices in ontology engineering, is fully interoperable with many domain resources and is easy to extend

A service broker for Intercloud computing

This thesis aims at assisting users in finding the most suitable Cloud resources taking into account their functional and non-functional SLA requirements. A key feature of the work is a Cloud service broker acting as mediator between consumers and Clouds. The research involves the implementation and evaluation of two SLA-aware match-making algorithms by use of a simulation environment. The work investigates also the optimal deployment of Multi-Cloud workflows on Intercloud environments

Enterprise application reuse: Semantic discovery of business grid services

Web services have emerged as a prominent paradigm for the development of distributed software systems as they provide the potential for software to be modularized in a way that functionality can be described, discovered and deployed in a platform independent manner over a network (e.g., intranets, extranets and the Internet). This paper examines an extension of this paradigm to encompass ‘Grid Services’, which enables software capabilities to be recast with an operational focus and support a heterogeneous mix of business software and data, termed a Business Grid - "the grid of semantic services". The current industrial representation of services is predominantly syntactic however, lacking the fundamental semantic underpinnings required to fulfill the goals of any semantically-oriented Grid. Consequently, the use of semantic technology in support of business software heterogeneity is investigated as a likely tool to support a diverse and distributed software inventory and user. Service discovery architecture is therefore developed that is (a) distributed in form, (2) supports distributed service knowledge and (3) automatically extends service knowledge (as greater descriptive precision is inferred from the operating application system). This discovery engine is used to execute several real-word scenarios in order to develop and test a framework for engineering such grid service knowledge. The examples presented comprise software components taken from a group of Investment Banking systems. Resulting from the research is a framework for engineering servic

The INCF Digital Atlasing Program: Report on Digital Atlasing Standards in the Rodent Brain

The goal of the INCF Digital Atlasing Program is to provide the vision and direction necessary to make the rapidly growing collection of multidimensional data of the rodent brain (images, gene expression, etc.) widely accessible and usable to the international research community. This Digital Brain Atlasing Standards Task Force was formed in May 2008 to investigate the state of rodent brain digital atlasing, and formulate standards, guidelines, and policy recommendations.

Our first objective has been the preparation of a detailed document that includes the vision and specific description of an infrastructure, systems and methods capable of serving the scientific goals of the community, as well as practical issues for achieving
the goals. This report builds on the 1st INCF Workshop on Mouse and Rat Brain Digital Atlasing Systems (Boline et al., 2007, _Nature Preceedings_, doi:10.1038/npre.2007.1046.1) and includes a more detailed analysis of both the current state and desired state of digital atlasing along with specific recommendations for achieving these goals

An Analysis of Service Ontologies

Services are increasingly shaping the world’s economic activity. Service provision and consumption have been profiting from advances in ICT, but the decentralization and heterogeneity of the involved service entities still pose engineering challenges. One of these challenges is to achieve semantic interoperability among these autonomous entities. Semantic web technology aims at addressing this challenge on a large scale, and has matured over the last years. This is evident from the various efforts reported in the literature in which service knowledge is represented in terms of ontologies developed either in individual research projects or in standardization bodies. This paper aims at analyzing the most relevant service ontologies available today for their suitability to cope with the service semantic interoperability challenge. We take the vision of the Internet of Services (IoS) as our motivation to identify the requirements for service ontologies. We adopt a formal approach to ontology design and evaluation in our analysis. We start by defining informal competency questions derived from a motivating scenario, and we identify relevant concepts and properties in service ontologies that match the formal ontological representation of these questions. We analyze the service ontologies with our concepts and questions, so that each ontology is positioned and evaluated according to its utility. The gaps we identify as the result of our analysis provide an indication of open challenges and future work

Semantically defined Analytics for Industrial Equipment Diagnostics

In this age of digitalization, industries everywhere accumulate massive amount of data such that it has become the lifeblood of the global economy. This data may come from various heterogeneous systems, equipment, components, sensors, systems and applications in many varieties (diversity of sources), velocities (high rate of changes) and volumes (sheer data size). Despite significant advances in the ability to collect, store, manage and filter data, the real value lies in the analytics. Raw data is meaningless, unless it is properly processed to actionable (business) insights. Those that know how to harness data effectively, have a decisive competitive advantage, through raising performance by making faster and smart decisions, improving short and long-term strategic planning, offering more user-centric products and services and fostering innovation. Two distinct paradigms in practice can be discerned within the field of analytics: semantic-driven (deductive) and data-driven (inductive). The first emphasizes logic as a way of representing the domain knowledge encoded in rules or ontologies and are often carefully curated and maintained. However, these models are often highly complex, and require intensive knowledge processing capabilities. Data-driven analytics employ machine learning (ML) to directly learn a model from the data with minimal human intervention. However, these models are tuned to trained data and context, making it difficult to adapt. Industries today that want to create value from data must master these paradigms in combination. However, there is great need in data analytics to seamlessly combine semantic-driven and data-driven processing techniques in an efficient and scalable architecture that allows extracting actionable insights from an extreme variety of data. In this thesis, we address these needs by providing: • A unified representation of domain-specific and analytical semantics, in form of ontology models called TechOnto Ontology Stack. It is highly expressive, platform-independent formalism to capture conceptual semantics of industrial systems such as technical system hierarchies, component partonomies etc and its analytical functional semantics. • A new ontology language Semantically defined Analytical Language (SAL) on top of the ontology model that extends existing DatalogMTL (a Horn fragment of Metric Temporal Logic) with analytical functions as first class citizens. • A method to generate semantic workflows using our SAL language. It helps in authoring, reusing and maintaining complex analytical tasks and workflows in an abstract fashion. • A multi-layer architecture that fuses knowledge- and data-driven analytics into a federated and distributed solution. To our knowledge, the work in this thesis is one of the first works to introduce and investigate the use of the semantically defined analytics in an ontology-based data access setting for industrial analytical applications. The reason behind focusing our work and evaluation on industrial data is due to (i) the adoption of semantic technology by the industries in general, and (ii) the common need in literature and in practice to allow domain expertise to drive the data analytics on semantically interoperable sources, while still harnessing the power of analytics to enable real-time data insights. Given the evaluation results of three use-case studies, our approach surpass state-of-the-art approaches for most application scenarios.Im Zeitalter der Digitalisierung sammeln die Industrien überall massive Daten-mengen, die zum Lebenselixier der Weltwirtschaft geworden sind. Diese Daten können aus verschiedenen heterogenen Systemen, Geräten, Komponenten, Sensoren, Systemen und Anwendungen in vielen Varianten (Vielfalt der Quellen), Geschwindigkeiten (hohe Änderungsrate) und Volumina (reine Datengröße) stammen. Trotz erheblicher Fortschritte in der Fähigkeit, Daten zu sammeln, zu speichern, zu verwalten und zu filtern, liegt der eigentliche Wert in der Analytik. Rohdaten sind bedeutungslos, es sei denn, sie werden ordnungsgemäß zu verwertbaren (Geschäfts-)Erkenntnissen verarbeitet. Wer weiß, wie man Daten effektiv nutzt, hat einen entscheidenden Wettbewerbsvorteil, indem er die Leistung steigert, indem er schnellere und intelligentere Entscheidungen trifft, die kurz- und langfristige strategische Planung verbessert, mehr benutzerorientierte Produkte und Dienstleistungen anbietet und Innovationen fördert. In der Praxis lassen sich im Bereich der Analytik zwei unterschiedliche Paradigmen unterscheiden: semantisch (deduktiv) und Daten getrieben (induktiv). Die erste betont die Logik als eine Möglichkeit, das in Regeln oder Ontologien kodierte Domänen-wissen darzustellen, und wird oft sorgfältig kuratiert und gepflegt. Diese Modelle sind jedoch oft sehr komplex und erfordern eine intensive Wissensverarbeitung. Datengesteuerte Analysen verwenden maschinelles Lernen (ML), um mit minimalem menschlichen Eingriff direkt ein Modell aus den Daten zu lernen. Diese Modelle sind jedoch auf trainierte Daten und Kontext abgestimmt, was die Anpassung erschwert. Branchen, die heute Wert aus Daten schaffen wollen, müssen diese Paradigmen in Kombination meistern. Es besteht jedoch ein großer Bedarf in der Daten-analytik, semantisch und datengesteuerte Verarbeitungstechniken nahtlos in einer effizienten und skalierbaren Architektur zu kombinieren, die es ermöglicht, aus einer extremen Datenvielfalt verwertbare Erkenntnisse zu gewinnen. In dieser Arbeit, die wir auf diese Bedürfnisse durch die Bereitstellung: • Eine einheitliche Darstellung der Domänen-spezifischen und analytischen Semantik in Form von Ontologie Modellen, genannt TechOnto Ontology Stack. Es ist ein hoch-expressiver, plattformunabhängiger Formalismus, die konzeptionelle Semantik industrieller Systeme wie technischer Systemhierarchien, Komponenten-partonomien usw. und deren analytische funktionale Semantik zu erfassen. • Eine neue Ontologie-Sprache Semantically defined Analytical Language (SAL) auf Basis des Ontologie-Modells das bestehende DatalogMTL (ein Horn fragment der metrischen temporären Logik) um analytische Funktionen als erstklassige Bürger erweitert. • Eine Methode zur Erzeugung semantischer workflows mit unserer SAL-Sprache. Es hilft bei der Erstellung, Wiederverwendung und Wartung komplexer analytischer Aufgaben und workflows auf abstrakte Weise. • Eine mehrschichtige Architektur, die Wissens- und datengesteuerte Analysen zu einer föderierten und verteilten Lösung verschmilzt. Nach unserem Wissen, die Arbeit in dieser Arbeit ist eines der ersten Werke zur Einführung und Untersuchung der Verwendung der semantisch definierten Analytik in einer Ontologie-basierten Datenzugriff Einstellung für industrielle analytische Anwendungen. Der Grund für die Fokussierung unserer Arbeit und Evaluierung auf industrielle Daten ist auf (i) die Übernahme semantischer Technologien durch die Industrie im Allgemeinen und (ii) den gemeinsamen Bedarf in der Literatur und in der Praxis zurückzuführen, der es der Fachkompetenz ermöglicht, die Datenanalyse auf semantisch inter-operablen Quellen voranzutreiben, und nutzen gleichzeitig die Leistungsfähigkeit der Analytik, um Echtzeit-Daten-einblicke zu ermöglichen. Aufgrund der Evaluierungsergebnisse von drei Anwendungsfällen Übertritt unser Ansatz für die meisten Anwendungsszenarien Modernste Ansätze

Perspectives on automated composition of workflows in the life sciences [version 1; peer review: 2 approved]

Scientific data analyses often combine several computational tools in automated pipelines, or workflows. Thousands of such workflows have been used in the life sciences, though their composition has remained a cumbersome manual process due to a lack of standards for annotation, assembly, and implementation. Recent technological advances have returned the long-standing vision of automated workflow composition into focus. This article summarizes a recent Lorentz Center workshop dedicated to automated composition of workflows in the life sciences. We survey previous initiatives to automate the composition process, and discuss the current state of the art and future perspectives. We start by drawing the “big picture” of the scientific workflow development life cycle, before surveying and discussing current methods, technologies and practices for semantic domain modelling, automation in workflow development, and workflow assessment. Finally, we derive a roadmap of individual and community-based actions to work toward the vision of automated workflow development in the forthcoming years. A central outcome of the workshop is a general description of the workflow life cycle in six stages: 1) scientific question or hypothesis, 2) conceptual workflow, 3) abstract workflow, 4) concrete workflow, 5) production workflow, and 6) scientific results. The transitions between stages are facilitated by diverse tools and methods, usually incorporating domain knowledge in some form. Formal semantic domain modelling is hard and often a bottleneck for the application of semantic technologies. However, life science communities have made considerable progress here in recent years and are continuously improving, renewing interest in the application of semantic technologies for workflow exploration, composition and instantiation. Combined with systematic benchmarking with reference data and large-scale deployment of production-stage workflows, such technologies enable a more systematic process of workflow development than we know today. We believe that this can lead to more robust, reusable, and sustainable workflows in the future.Stian Soiland-Reyes was supported by BioExcel-2 Centre of Excellence, funded by European Commission Horizon 2020 programme under European Commission contract H2020-INFRAEDI-02-2018 823830. Carole Goble was supported by EOSC-Life, funded by European Commission Horizon 2020 programme under grant agreement H2020-INFRAEOSC-2018-2 824087. We gratefully acknowledge the financial support from the Lorentz Center, ELIXIR, and the Leiden University Medical Center (LUMC) that made the workshop possible. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscriptPeer Reviewed"Article signat per 33 autors/es: Anna-Lena Lamprecht , Magnus Palmblad, Jon Ison, Veit Schwämmle , Mohammad Sadnan Al Manir, Ilkay Altintas, Christopher J. O. Baker, Ammar Ben Hadj Amor, Salvador Capella-Gutierrez, Paulos Charonyktakis, Michael R. Crusoe, Yolanda Gil, Carole Goble, Timothy J. Griffin , Paul Groth , Hans Ienasescu, Pratik Jagtap, Matúš Kalaš , Vedran Kasalica, Alireza Khanteymoori , Tobias Kuhn12, Hailiang Mei, Hervé Ménager, Steffen Möller, Robin A. Richardson, Vincent Robert9, Stian Soiland-Reyes, Robert Stevens, Szoke Szaniszlo, Suzan Verberne, Aswin Verhoeven, Katherine Wolstencroft "Postprint (published version