3,771 research outputs found

    Histopathological image analysis : a review

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    Over the past decade, dramatic increases in computational power and improvement in image analysis algorithms have allowed the development of powerful computer-assisted analytical approaches to radiological data. With the recent advent of whole slide digital scanners, tissue histopathology slides can now be digitized and stored in digital image form. Consequently, digitized tissue histopathology has now become amenable to the application of computerized image analysis and machine learning techniques. Analogous to the role of computer-assisted diagnosis (CAD) algorithms in medical imaging to complement the opinion of a radiologist, CAD algorithms have begun to be developed for disease detection, diagnosis, and prognosis prediction to complement the opinion of the pathologist. In this paper, we review the recent state of the art CAD technology for digitized histopathology. This paper also briefly describes the development and application of novel image analysis technology for a few specific histopathology related problems being pursued in the United States and Europe

    The Data Big Bang and the Expanding Digital Universe: High-Dimensional, Complex and Massive Data Sets in an Inflationary Epoch

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    Recent and forthcoming advances in instrumentation, and giant new surveys, are creating astronomical data sets that are not amenable to the methods of analysis familiar to astronomers. Traditional methods are often inadequate not merely because of the size in bytes of the data sets, but also because of the complexity of modern data sets. Mathematical limitations of familiar algorithms and techniques in dealing with such data sets create a critical need for new paradigms for the representation, analysis and scientific visualization (as opposed to illustrative visualization) of heterogeneous, multiresolution data across application domains. Some of the problems presented by the new data sets have been addressed by other disciplines such as applied mathematics, statistics and machine learning and have been utilized by other sciences such as space-based geosciences. Unfortunately, valuable results pertaining to these problems are mostly to be found only in publications outside of astronomy. Here we offer brief overviews of a number of concepts, techniques and developments, some "old" and some new. These are generally unknown to most of the astronomical community, but are vital to the analysis and visualization of complex datasets and images. In order for astronomers to take advantage of the richness and complexity of the new era of data, and to be able to identify, adopt, and apply new solutions, the astronomical community needs a certain degree of awareness and understanding of the new concepts. One of the goals of this paper is to help bridge the gap between applied mathematics, artificial intelligence and computer science on the one side and astronomy on the other.Comment: 24 pages, 8 Figures, 1 Table. Accepted for publication: "Advances in Astronomy, special issue "Robotic Astronomy

    Fuzzy spectral and spatial feature integration for classification of nonferrous materials in hyperspectral data

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    Hyperspectral data allows the construction of more elaborate models to sample the properties of the nonferrous materials than the standard RGB color representation. In this paper, the nonferrous waste materials are studied as they cannot be sorted by classical procedures due to their color, weight and shape similarities. The experimental results presented in this paper reveal that factors such as the various levels of oxidization of the waste materials and the slight differences in their chemical composition preclude the use of the spectral features in a simplistic manner for robust material classification. To address these problems, the proposed FUSSER (fuzzy spectral and spatial classifier) algorithm detailed in this paper merges the spectral and spatial features to obtain a combined feature vector that is able to better sample the properties of the nonferrous materials than the single pixel spectral features when applied to the construction of multivariate Gaussian distributions. This approach allows the implementation of statistical region merging techniques in order to increase the performance of the classification process. To achieve an efficient implementation, the dimensionality of the hyperspectral data is reduced by constructing bio-inspired spectral fuzzy sets that minimize the amount of redundant information contained in adjacent hyperspectral bands. The experimental results indicate that the proposed algorithm increased the overall classification rate from 44% using RGB data up to 98% when the spectral-spatial features are used for nonferrous material classification

    GETNET: A General End-to-end Two-dimensional CNN Framework for Hyperspectral Image Change Detection

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    Change detection (CD) is an important application of remote sensing, which provides timely change information about large-scale Earth surface. With the emergence of hyperspectral imagery, CD technology has been greatly promoted, as hyperspectral data with the highspectral resolution are capable of detecting finer changes than using the traditional multispectral imagery. Nevertheless, the high dimension of hyperspectral data makes it difficult to implement traditional CD algorithms. Besides, endmember abundance information at subpixel level is often not fully utilized. In order to better handle high dimension problem and explore abundance information, this paper presents a General End-to-end Two-dimensional CNN (GETNET) framework for hyperspectral image change detection (HSI-CD). The main contributions of this work are threefold: 1) Mixed-affinity matrix that integrates subpixel representation is introduced to mine more cross-channel gradient features and fuse multi-source information; 2) 2-D CNN is designed to learn the discriminative features effectively from multi-source data at a higher level and enhance the generalization ability of the proposed CD algorithm; 3) A new HSI-CD data set is designed for the objective comparison of different methods. Experimental results on real hyperspectral data sets demonstrate the proposed method outperforms most of the state-of-the-arts
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