Exploiting Nonlinear Recurrence and Fractal Scaling Properties for Voice Disorder Detection

Background: Voice disorders affect patients profoundly, and acoustic tools can potentially measure voice function objectively. Disordered sustained vowels exhibit wide-ranging phenomena, from nearly periodic to highly complex, aperiodic vibrations, and increased "breathiness". Modelling and surrogate data studies have shown significant nonlinear and non-Gaussian random properties in these sounds. Nonetheless, existing tools are limited to analysing voices displaying near periodicity, and do not account for this inherent biophysical nonlinearity and non-Gaussian randomness, often using linear signal processing methods insensitive to these properties. They do not directly measure the two main biophysical symptoms of disorder: complex nonlinear aperiodicity, and turbulent, aeroacoustic, non-Gaussian randomness. Often these tools cannot be applied to more severe disordered voices, limiting their clinical usefulness.

Methods: This paper introduces two new tools to speech analysis: recurrence and fractal scaling, which overcome the range limitations of existing tools by addressing directly these two symptoms of disorder, together reproducing a "hoarseness" diagram. A simple bootstrapped classifier then uses these two features to distinguish normal from disordered voices.

Results: On a large database of subjects with a wide variety of voice disorders, these new techniques can distinguish normal from disordered cases, using quadratic discriminant analysis, to overall correct classification performance of 91.8% plus or minus 2.0%. The true positive classification performance is 95.4% plus or minus 3.2%, and the true negative performance is 91.5% plus or minus 2.3% (95% confidence). This is shown to outperform all combinations of the most popular classical tools.

Conclusions: Given the very large number of arbitrary parameters and computational complexity of existing techniques, these new techniques are far simpler and yet achieve clinically useful classification performance using only a basic classification technique. They do so by exploiting the inherent nonlinearity and turbulent randomness in disordered voice signals. They are widely applicable to the whole range of disordered voice phenomena by design. These new measures could therefore be used for a variety of practical clinical purposes.
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Improving the Speech Intelligibility By Cochlear Implant Users

In this thesis, we focus on improving the intelligibility of speech for cochlear implants (CI) users. As an auditory prosthetic device, CI can restore hearing sensations for most patients with profound hearing loss in both ears in a quiet background. However, CI users still have serious problems in understanding speech in noisy and reverberant environments. Also, bandwidth limitation, missing temporal fine structures, and reduced spectral resolution due to a limited number of electrodes are other factors that raise the difficulty of hearing in noisy conditions for CI users, regardless of the type of noise. To mitigate these difficulties for CI listener, we investigate several contributing factors such as the effects of low harmonics on tone identification in natural and vocoded speech, the contribution of matched envelope dynamic range to the binaural benefits and contribution of low-frequency harmonics to tone identification in quiet and six-talker babble background. These results revealed several promising methods for improving speech intelligibility for CI patients. In addition, we investigate the benefits of voice conversion in improving speech intelligibility for CI users, which was motivated by an earlier study showing that familiarity with a talker’s voice can improve understanding of the conversation. Research has shown that when adults are familiar with someone’s voice, they can more accurately – and even more quickly – process and understand what the person is saying. This theory identified as the “familiar talker advantage” was our motivation to examine its effect on CI patients using voice conversion technique. In the present research, we propose a new method based on multi-channel voice conversion to improve the intelligibility of transformed speeches for CI patients

Digital Signal Processing

Contains an introduction and reports on seventeen research projects.U.S. Navy - Office of Naval Research (Contract N00014-77-C-0266)Amoco Foundation FellowshipU.S. Navy - Office of Naval Research (Contract N00014-81-K-0742)National Science Foundation (Grant ECS80-07102)U.S. Army Research Office (Contract DAAG29-81-K-0073)Hughes Aircraft Company FellowshipAmerican Edwards Labs. GrantWhitaker Health Sciences FundPfeiffer Foundation GrantSchlumberger-Doll Research Center FellowshipGovernment of Pakistan ScholarshipU.S. Navy - Office of Naval Research (Contract N00014-77-C-0196)National Science Foundation (Grant ECS79-15226)Hertz Foundation Fellowshi

Binaural scene analysis : localization, detection and recognition of speakers in complex acoustic scenes

The human auditory system has the striking ability to robustly localize and recognize a specific target source in complex acoustic environments while ignoring interfering sources. Surprisingly, this remarkable capability, which is referred to as auditory scene analysis, is achieved by only analyzing the waveforms reaching the two ears. Computers, however, are presently not able to compete with the performance achieved by the human auditory system, even in the restricted paradigm of confronting a computer algorithm based on binaural signals with a highly constrained version of auditory scene analysis, such as localizing a sound source in a reverberant environment or recognizing a speaker in the presence of interfering noise. In particular, the problem of focusing on an individual speech source in the presence of competing speakers, termed the cocktail party problem, has been proven to be extremely challenging for computer algorithms. The primary objective of this thesis is the development of a binaural scene analyzer that is able to jointly localize, detect and recognize multiple speech sources in the presence of reverberation and interfering noise. The processing of the proposed system is divided into three main stages: localization stage, detection of speech sources, and recognition of speaker identities. The only information that is assumed to be known a priori is the number of target speech sources that are present in the acoustic mixture. Furthermore, the aim of this work is to reduce the performance gap between humans and machines by improving the performance of the individual building blocks of the binaural scene analyzer. First, a binaural front-end inspired by auditory processing is designed to robustly determine the azimuth of multiple, simultaneously active sound sources in the presence of reverberation. The localization model builds on the supervised learning of azimuthdependent binaural cues, namely interaural time and level differences. Multi-conditional training is performed to incorporate the uncertainty of these binaural cues resulting from reverberation and the presence of competing sound sources. Second, a speech detection module that exploits the distinct spectral characteristics of speech and noise signals is developed to automatically select azimuthal positions that are likely to correspond to speech sources. Due to the established link between the localization stage and the recognition stage, which is realized by the speech detection module, the proposed binaural scene analyzer is able to selectively focus on a predefined number of speech sources that are positioned at unknown spatial locations, while ignoring interfering noise sources emerging from other spatial directions. Third, the speaker identities of all detected speech sources are recognized in the final stage of the model. To reduce the impact of environmental noise on the speaker recognition performance, a missing data classifier is combined with the adaptation of speaker models using a universal background model. This combination is particularly beneficial in nonstationary background noise