3,776 research outputs found
Spike-and-Slab Priors for Function Selection in Structured Additive Regression Models
Structured additive regression provides a general framework for complex
Gaussian and non-Gaussian regression models, with predictors comprising
arbitrary combinations of nonlinear functions and surfaces, spatial effects,
varying coefficients, random effects and further regression terms. The large
flexibility of structured additive regression makes function selection a
challenging and important task, aiming at (1) selecting the relevant
covariates, (2) choosing an appropriate and parsimonious representation of the
impact of covariates on the predictor and (3) determining the required
interactions. We propose a spike-and-slab prior structure for function
selection that allows to include or exclude single coefficients as well as
blocks of coefficients representing specific model terms. A novel
multiplicative parameter expansion is required to obtain good mixing and
convergence properties in a Markov chain Monte Carlo simulation approach and is
shown to induce desirable shrinkage properties. In simulation studies and with
(real) benchmark classification data, we investigate sensitivity to
hyperparameter settings and compare performance to competitors. The flexibility
and applicability of our approach are demonstrated in an additive piecewise
exponential model with time-varying effects for right-censored survival times
of intensive care patients with sepsis. Geoadditive and additive mixed logit
model applications are discussed in an extensive appendix
Penalized Likelihood and Bayesian Function Selection in Regression Models
Challenging research in various fields has driven a wide range of
methodological advances in variable selection for regression models with
high-dimensional predictors. In comparison, selection of nonlinear functions in
models with additive predictors has been considered only more recently. Several
competing suggestions have been developed at about the same time and often do
not refer to each other. This article provides a state-of-the-art review on
function selection, focusing on penalized likelihood and Bayesian concepts,
relating various approaches to each other in a unified framework. In an
empirical comparison, also including boosting, we evaluate several methods
through applications to simulated and real data, thereby providing some
guidance on their performance in practice
Generalized Functional Additive Mixed Models
We propose a comprehensive framework for additive regression models for
non-Gaussian functional responses, allowing for multiple (partially) nested or
crossed functional random effects with flexible correlation structures for,
e.g., spatial, temporal, or longitudinal functional data as well as linear and
nonlinear effects of functional and scalar covariates that may vary smoothly
over the index of the functional response. Our implementation handles
functional responses from any exponential family distribution as well as many
others like Beta- or scaled non-central -distributions. Development is
motivated by and evaluated on an application to large-scale longitudinal
feeding records of pigs. Results in extensive simulation studies as well as
replications of two previously published simulation studies for generalized
functional mixed models demonstrate the good performance of our proposal. The
approach is implemented in well-documented open source software in the "pffr()"
function in R-package "refund"
Global sensitivity analysis of computer models with functional inputs
Global sensitivity analysis is used to quantify the influence of uncertain
input parameters on the response variability of a numerical model. The common
quantitative methods are applicable to computer codes with scalar input
variables. This paper aims to illustrate different variance-based sensitivity
analysis techniques, based on the so-called Sobol indices, when some input
variables are functional, such as stochastic processes or random spatial
fields. In this work, we focus on large cpu time computer codes which need a
preliminary meta-modeling step before performing the sensitivity analysis. We
propose the use of the joint modeling approach, i.e., modeling simultaneously
the mean and the dispersion of the code outputs using two interlinked
Generalized Linear Models (GLM) or Generalized Additive Models (GAM). The
``mean'' model allows to estimate the sensitivity indices of each scalar input
variables, while the ``dispersion'' model allows to derive the total
sensitivity index of the functional input variables. The proposed approach is
compared to some classical SA methodologies on an analytical function. Lastly,
the proposed methodology is applied to a concrete industrial computer code that
simulates the nuclear fuel irradiation
Global Sensitivity Analysis of Stochastic Computer Models with joint metamodels
The global sensitivity analysis method, used to quantify the influence of
uncertain input variables on the response variability of a numerical model, is
applicable to deterministic computer code (for which the same set of input
variables gives always the same output value). This paper proposes a global
sensitivity analysis methodology for stochastic computer code (having a
variability induced by some uncontrollable variables). The framework of the
joint modeling of the mean and dispersion of heteroscedastic data is used. To
deal with the complexity of computer experiment outputs, non parametric joint
models (based on Generalized Additive Models and Gaussian processes) are
discussed. The relevance of these new models is analyzed in terms of the
obtained variance-based sensitivity indices with two case studies. Results show
that the joint modeling approach leads accurate sensitivity index estimations
even when clear heteroscedasticity is present
Boosting Functional Response Models for Location, Scale and Shape with an Application to Bacterial Competition
We extend Generalized Additive Models for Location, Scale, and Shape (GAMLSS)
to regression with functional response. This allows us to simultaneously model
point-wise mean curves, variances and other distributional parameters of the
response in dependence of various scalar and functional covariate effects. In
addition, the scope of distributions is extended beyond exponential families.
The model is fitted via gradient boosting, which offers inherent model
selection and is shown to be suitable for both complex model structures and
highly auto-correlated response curves. This enables us to analyze bacterial
growth in \textit{Escherichia coli} in a complex interaction scenario,
fruitfully extending usual growth models.Comment: bootstrap confidence interval type uncertainty bounds added; minor
changes in formulation
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