Improved Otsu and Kapur approach for white blood cells segmentation based on LebTLBO optimization for the detection of Leukemia.

The diagnosis of leukemia involves the detection of the abnormal characteristics of blood cells by a trained pathologist. Currently, this is done manually by observing the morphological characteristics of white blood cells in the microscopic images. Though there are some equipment- based and chemical-based tests available, the use and adaptation of the automated computer vision-based system is still an issue. There are certain software frameworks available in the literature; however, they are still not being adopted commercially. So there is a need for an automated and software- based framework for the detection of leukemia. In software-based detection, segmentation is the first critical stage that outputs the region of interest for further accurate diagnosis. Therefore, this paper explores an efficient and hybrid segmentation that proposes a more efficient and effective system for leukemia diagnosis. A very popular publicly available database, the acute lymphoblastic leukemia image database (ALL-IDB), is used in this research. First, the images are pre-processed and segmentation is done using Multilevel thresholding with Otsu and Kapur methods. To further optimize the segmentation performance, the Learning enthusiasm-based teaching-learning-based optimization (LebTLBO) algorithm is employed. Different metrics are used for measuring the system performance. A comparative analysis of the proposed methodology is done with existing benchmarks methods. The proposed approach has proven to be better than earlier techniques with measuring parameters of PSNR and Similarity index. The result shows a significant improvement in the performance measures with optimizing threshold algorithms and the LebTLBO technique

Soft computing applied to optimization, computer vision and medicine

Artificial intelligence has permeated almost every area of life in modern society, and its significance continues to grow. As a result, in recent years, Soft Computing has emerged as a powerful set of methodologies that propose innovative and robust solutions to a variety of complex problems. Soft Computing methods, because of their broad range of application, have the potential to significantly improve human living conditions. The motivation for the present research emerged from this background and possibility. This research aims to accomplish two main objectives: On the one hand, it endeavors to bridge the gap between Soft Computing techniques and their application to intricate problems. On the other hand, it explores the hypothetical benefits of Soft Computing methodologies as novel effective tools for such problems. This thesis synthesizes the results of extensive research on Soft Computing methods and their applications to optimization, Computer Vision, and medicine. This work is composed of several individual projects, which employ classical and new optimization algorithms. The manuscript presented here intends to provide an overview of the different aspects of Soft Computing methods in order to enable the reader to reach a global understanding of the field. Therefore, this document is assembled as a monograph that summarizes the outcomes of these projects across 12 chapters. The chapters are structured so that they can be read independently. The key focus of this work is the application and design of Soft Computing approaches for solving problems in the following: Block Matching, Pattern Detection, Thresholding, Corner Detection, Template Matching, Circle Detection, Color Segmentation, Leukocyte Detection, and Breast Thermogram Analysis. One of the outcomes presented in this thesis involves the development of two evolutionary approaches for global optimization. These were tested over complex benchmark datasets and showed promising results, thus opening the debate for future applications. Moreover, the applications for Computer Vision and medicine presented in this work have highlighted the utility of different Soft Computing methodologies in the solution of problems in such subjects. A milestone in this area is the translation of the Computer Vision and medical issues into optimization problems. Additionally, this work also strives to provide tools for combating public health issues by expanding the concepts to automated detection and diagnosis aid for pathologies such as Leukemia and breast cancer. The application of Soft Computing techniques in this field has attracted great interest worldwide due to the exponential growth of these diseases. Lastly, the use of Fuzzy Logic, Artificial Neural Networks, and Expert Systems in many everyday domestic appliances, such as washing machines, cookers, and refrigerators is now a reality. Many other industrial and commercial applications of Soft Computing have also been integrated into everyday use, and this is expected to increase within the next decade. Therefore, the research conducted here contributes an important piece for expanding these developments. The applications presented in this work are intended to serve as technological tools that can then be used in the development of new devices

Image similarity in medical images

Recent experiments have indicated a strong influence of the substrate grain orientation on the self-ordering in anodic porous alumina. Anodic porous alumina with straight pore channels grown in a stable, self-ordered manner is formed on (001) oriented Al grain, while disordered porous pattern is formed on (101) oriented Al grain with tilted pore channels growing in an unstable manner. In this work, numerical simulation of the pore growth process is carried out to understand this phenomenon. The rate-determining step of the oxide growth is assumed to be the Cabrera-Mott barrier at the oxide/electrolyte (o/e) interface, while the substrate is assumed to determine the ratio β between the ionization and oxidation reactions at the metal/oxide (m/o) interface. By numerically solving the electric field inside a growing porous alumina during anodization, the migration rates of the ions and hence the evolution of the o/e and m/o interfaces are computed. The simulated results show that pore growth is more stable when β is higher. A higher β corresponds to more Al ionized and migrating away from the m/o interface rather than being oxidized, and hence a higher retained O:Al ratio in the oxide. Experimentally measured oxygen content in the self-ordered porous alumina on (001) Al is indeed found to be about 3% higher than that in the disordered alumina on (101) Al, in agreement with the theoretical prediction. The results, therefore, suggest that ionization on (001) Al substrate is relatively easier than on (101) Al, and this leads to the more stable growth of the pore channels on (001) Al

Segmentation Method for Pathological Brain Tumor and Accurate Detection using MRI

Image segmentation is challenging task in field of medical image processing. Magnetic resonance imaging is helpful to doctor for detection of human brain tumor within three sources of images (axil, corneal, sagittal). MR images are nosier and detection of brain tumor location as feature is more complicated. Level set methods have been applied but due to human interaction they are affected so appropriate contour has been generated in discontinuous regions and pathological human brain tumor portion highlighted after applying binarization, removing unessential objects; therefore contour has been generated. Then to classify tumor for segmentation hybrid Fuzzy K Mean-Self Organization Mapping (FKM-SOM) for variation of intensities is used. For improved segmented accuracy, classification has been performed, mainly features are extracted using Discrete Wavelet Transformation (DWT) then reduced using Principal Component Analysis (PCA). Thirteen features from every image of dataset have been classified for accuracy using Support Vector Machine (SVM) kernel classification (RBF, linear, polygon) so results have been achieved using evaluation parameters like Fscore, Precision, accuracy, specificity and recall

Information theoretic thresholding techniques based on particle swarm optimization.

In this dissertation, we discuss multi-level image thresholding techniques based on information theoretic entropies. In order to apply the correlation information of neighboring pixels of an image to obtain better segmentation results, we propose several multi-level thresholding models by using Gray-Level & Local-Average histogram (GLLA) and Gray-Level & Local-Variance histogram (GLLV). Firstly, a RGB color image thresholding model based on GLLA histogram and Tsallis-Havrda-Charv\u27at entropy is discussed. We validate the multi-level thresholding criterion function by using mathematical induction. For each component image, we assign the mean value from each thresholded class to obtain three segmented component images independently. Then we obtain the segmented color image by combining the three segmented component images. Secondly, we use the GLLV histogram to propose three novel entropic multi-level thresholding models based on Shannon entropy, R\u27enyi entropy and Tsallis-Havrda-Charv\u27at entropy respectively. Then we apply these models on the three components of a RGB color image to complete the RGB color image segmentation. An entropic thresholding model is mostly about searching for the optimal threshold values by maximizing or minimizing a criterion function. We apply particle swarm optimization (PSO) algorithm to search the optimal threshold values for all the models. We conduct the experiments extensively on The Berkeley Segmentation Dataset and Benchmark (BSDS300) and calculate the average four performance indices (Probability Rand Index, PRI, Global Consistency Error, GCE, Variation of Information, VOI and Boundary Displacement Error, BDE) to show the effectiveness and reasonability of the proposed models

A precise bare simulation approach to the minimization of some distances. Foundations

In information theory -- as well as in the adjacent fields of statistics, machine learning, artificial intelligence, signal processing and pattern recognition -- many flexibilizations of the omnipresent Kullback-Leibler information distance (relative entropy) and of the closely related Shannon entropy have become frequently used tools. To tackle corresponding constrained minimization (respectively maximization) problems by a newly developed dimension-free bare (pure) simulation method, is the main goal of this paper. Almost no assumptions (like convexity) on the set of constraints are needed, within our discrete setup of arbitrary dimension, and our method is precise (i.e., converges in the limit). As a side effect, we also derive an innovative way of constructing new useful distances/divergences. To illustrate the core of our approach, we present numerous examples. The potential for widespread applicability is indicated, too; in particular, we deliver many recent references for uses of the involved distances/divergences and entropies in various different research fields (which may also serve as an interdisciplinary interface)

Cooperative Swarm Intelligence Algorithms for Adaptive Multilevel Thresholding Segmentation of COVID-19 CT-Scan Images

The Coronavirus Disease 2019 (COVID-19) is widespread throughout the world and poses a serious threat to public health and safety. A COVID-19 infection can be recognized using computed tomography (CT) scans. To enhance the categorization, some image segmentation techniques are presented to extract regions of interest from COVID-19 CT images. Multi-level thresholding (MLT) is one of the simplest and most effective image segmentation approaches, especially for grayscale images like CT scan images. Traditional image segmentation methods use histogram approaches; however, these approaches encounter some limitations. Now, swarm intelligence inspired meta-heuristic algorithms have been applied to resolve MLT, deemed an NP-hard optimization task. Despite the advantages of using meta-heuristics to solve global optimization tasks, each approach has its own drawbacks. However, the common flaw for most meta-heuristic algorithms is that they are unable to maintain the diversity of their population during the search, which means they might not always converge to the global optimum. This study proposes a cooperative swarm intelligence-based MLT image segmentation approach that hybridizes the advantages of parallel meta-heuristics and MLT for developing an efficient image segmentation method for COVID-19 CT images. An efficient cooperative model-based meta-heuristic called the CPGH is developed based on three practical algorithms: particle swarm optimization (PSO), grey wolf optimizer (GWO), and Harris hawks optimization (HHO). In the cooperative model, the applied algorithms are executed concurrently, and a number of potential solutions are moved across their populations through a procedure called migration after a set number of generations. The CPGH model can solve the image segmentation problem using MLT image segmentation. The proposed CPGH is evaluated using three objective functions, cross-entropy, Otsu’s, and Tsallis, over the COVID-19 CT images selected from open-sourced datasets. Various evaluation metrics covering peak signal-to-noise ratio (PSNR), structural similarity index (SSIM), and universal quality image index (UQI) were employed to quantify the segmentation quality. The overall ranking results of the segmentation quality metrics indicate that the performance of the proposed CPGH is better than conventional PSO, GWO, and HHO algorithms and other state-of-the-art methods for MLT image segmentation. On the tested COVID-19 CT images, the CPGH offered an average PSNR of 24.8062, SSIM of 0.8818, and UQI of 0.9097 using 20 thresholds