7,716 research outputs found

    Accelerated Particle Swarm Optimization and Support Vector Machine for Business Optimization and Applications

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    Business optimization is becoming increasingly important because all business activities aim to maximize the profit and performance of products and services, under limited resources and appropriate constraints. Recent developments in support vector machine and metaheuristics show many advantages of these techniques. In particular, particle swarm optimization is now widely used in solving tough optimization problems. In this paper, we use a combination of a recently developed Accelerated PSO and a nonlinear support vector machine to form a framework for solving business optimization problems. We first apply the proposed APSO-SVM to production optimization, and then use it for income prediction and project scheduling. We also carry out some parametric studies and discuss the advantages of the proposed metaheuristic SVM.Comment: 12 page

    Multiobjective strategies for New Product Development in the pharmaceutical industry

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    New Product Development (NPD) constitutes a challenging problem in the pharmaceutical industry, due to the characteristics of the development pipeline. Formally, the NPD problem can be stated as follows: select a set of R&D projects from a pool of candidate projects in order to satisfy several criteria (economic profitability, time to market) while coping with the uncertain nature of the projects. More precisely, the recurrent key issues are to determine the projects to develop once target molecules have been identified, their order and the level of resources to assign. In this context, the proposed approach combines discrete event stochastic simulation (Monte Carlo approach) with multiobjective genetic algorithms (NSGAII type, Non-Sorted Genetic Algorithm II) to optimize the highly combinatorial portfolio management problem. In that context, Genetic Algorithms (GAs) are particularly attractive for treating this kind of problem, due to their ability to directly lead to the so-called Pareto front and to account for the combinatorial aspect. This work is illustrated with a study case involving nine interdependent new product candidates targeting three diseases. An analysis is performed for this test bench on the different pairs of criteria both for the bi- and tricriteria optimization: large portfolios cause resource queues and delays time to launch and are eliminated by the bi- and tricriteria optimization strategy. The optimization strategy is thus interesting to detect the sequence candidates. Time is an important criterion to consider simultaneously with NPV and risk criteria. The order in which drugs are released in the pipeline is of great importance as with scheduling problems

    Multiobjective strategies for New Product Development in the pharmaceutical industry

    Get PDF
    New Product Development (NPD) constitutes a challenging problem in the pharmaceutical industry, due to the characteristics of the development pipeline. Formally, the NPD problem can be stated as follows: select a set of R&D projects from a pool of candidate projects in order to satisfy several criteria (economic profitability, time to market) while coping with the uncertain nature of the projects. More precisely, the recurrent key issues are to determine the projects to develop once target molecules have been identified, their order and the level of resources to assign. In this context, the proposed approach combines discrete event stochastic simulation (Monte Carlo approach) with multiobjective genetic algorithms (NSGAII type, Non-Sorted Genetic Algorithm II) to optimize the highly combinatorial portfolio management problem. In that context, Genetic Algorithms (GAs) are particularly attractive for treating this kind of problem, due to their ability to directly lead to the so-called Pareto front and to account for the combinatorial aspect. This work is illustrated with a study case involving nine interdependent new product candidates targeting three diseases. An analysis is performed for this test bench on the different pairs of criteria both for the bi- and tricriteria optimization: large portfolios cause resource queues and delays time to launch and are eliminated by the bi- and tricriteria optimization strategy. The optimization strategy is thus interesting to detect the sequence candidates. Time is an important criterion to consider simultaneously with NPV and risk criteria. The order in which drugs are released in the pipeline is of great importance as with scheduling problems

    A Review on Energy Consumption Optimization Techniques in IoT Based Smart Building Environments

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    In recent years, due to the unnecessary wastage of electrical energy in residential buildings, the requirement of energy optimization and user comfort has gained vital importance. In the literature, various techniques have been proposed addressing the energy optimization problem. The goal of each technique was to maintain a balance between user comfort and energy requirements such that the user can achieve the desired comfort level with the minimum amount of energy consumption. Researchers have addressed the issue with the help of different optimization algorithms and variations in the parameters to reduce energy consumption. To the best of our knowledge, this problem is not solved yet due to its challenging nature. The gap in the literature is due to the advancements in the technology and drawbacks of the optimization algorithms and the introduction of different new optimization algorithms. Further, many newly proposed optimization algorithms which have produced better accuracy on the benchmark instances but have not been applied yet for the optimization of energy consumption in smart homes. In this paper, we have carried out a detailed literature review of the techniques used for the optimization of energy consumption and scheduling in smart homes. The detailed discussion has been carried out on different factors contributing towards thermal comfort, visual comfort, and air quality comfort. We have also reviewed the fog and edge computing techniques used in smart homes

    Intelligent perturbation algorithms to space scheduling optimization

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    The limited availability and high cost of crew time and scarce resources make optimization of space operations critical. Advances in computer technology coupled with new iterative search techniques permit the near optimization of complex scheduling problems that were previously considered computationally intractable. Described here is a class of search techniques called Intelligent Perturbation Algorithms. Several scheduling systems which use these algorithms to optimize the scheduling of space crew, payload, and resource operations are also discussed

    Longterm schedule optimization of an underground mine under geotechnical and ventilation constraints using SOT

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    Long-term mine scheduling is complex as well time and labour intensive. Yet in the mainstream of the mining industry, there is no computing program for schedule optimization and, in consequence, schedules are still created manually. The objective of this study was to compare a base case schedule generated with the Enhanced Production Scheduler (EPS®) and an optimized schedule generated with the Schedule Optimization Tool (SOT). The intent of having an optimized schedule is to improve the project value for underground mines. This study shows that SOT generates mine schedules that improve the Net Present Value (NPV) associated with orebody extraction. It does so by means of systematically and automatically exploring the options to vary the sequence and timing of mine activities, subject to constraints. First, a conventional scheduling method (EPS®) was adopted to identify a schedule of mining activities that satisfied basic sets of constraints, including physical adjacencies of mining activities and operational resource capacity. Additional constraint scenarios explored were geotechnical and ventilation, which negatively effect development rates. Next, the automated SOT procedure was applied to determine whether the schedules could be improved upon. It was demonstrated that SOT permitted the rapid re-assessment of project value when new constraint scenarios were applied. This study showed that the automated schedule optimization added value to the project every time it was applied. In addition, the reoptimizing and re-evaluating was quickly achieved. Therefore, the tool used in this research produced more optimized schedules than those produced using conventional scheduling methods.Master of Applied Science (MASc) in Natural Resources Engineerin

    An efficient ant colony system based on receding horizon control for the aircraft arrival sequencing and scheduling problem

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    The aircraft arrival sequencing and scheduling (ASS) problem is a salient problem in air traffic control (ATC), which proves to be nondeterministic polynomial (NP) hard. This paper formulates the ASS problem in the form of a permutation problem and proposes a new solution framework that makes the first attempt at using an ant colony system (ACS) algorithm based on the receding horizon control (RHC) to solve it. The resultant RHC-improved ACS algorithm for the ASS problem (termed the RHC-ACS-ASS algorithm) is robust, effective, and efficient, not only due to that the ACS algorithm has a strong global search ability and has been proven to be suitable for these kinds of NP-hard problems but also due to that the RHC technique can divide the problem with receding time windows to reduce the computational burden and enhance the solution's quality. The RHC-ACS-ASS algorithm is extensively tested on the cases from the literatures and the cases randomly generated. Comprehensive investigations are also made for the evaluation of the influences of ACS and RHC parameters on the performance of the algorithm. Moreover, the proposed algorithm is further enhanced by using a two-opt exchange heuristic local search. Experimental results verify that the proposed RHC-ACS-ASS algorithm generally outperforms ordinary ACS without using the RHC technique and genetic algorithms (GAs) in solving the ASS problems and offers high robustness, effectiveness, and efficienc
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