Enrichment of Wind Turbine Health History for Condition-Based Maintenance

This research develops a methodology for and shows the benefit of linking records of wind turbine maintenance. It analyses commercially sensitive real-world maintenance records with the aim of improving the productivity of offshore wind farms. The novel achievements of this research are that it applies multi-feature record linkage techniques to maintenance data, that it applies statistical techniques for the interval estimation of a binomial proportion to record linkage techniques and that it estimates the distribution of the coverage error of statistical techniques for the interval estimation of a binomial proportion. The main contribution of this research is a process for the enrichment of offshore wind turbine health history. The economic productivity of a wind farm depends on the price of electricity and on the suitability of the weather, both of which are beyond the control of a maintenance team, but also on the cost of operating the wind farm, on the cost of maintaining the wind turbines and on how much of the wind farm’s potential production of electricity is lost to outages. Improvements in maintenance scheduling, in condition-based maintenance, in troubleshooting and in the measurement of maintenance effectiveness all require knowledge of the health history of the plant. To this end, this thesis presents new techniques for linking together existing records of offshore wind turbine health history. Multi-feature record linkage techniques are used to link records of maintenance data together. Both the quality of record linkage and the uncertainty of that quality are assessed. The quality of record linkage was measured by comparing the generated set of linked records to a gold standard set of linked records identified in collaboration with offshore wind turbine maintenance experts. The process for the enrichment of offshore wind turbine health history developed in this research requires a vector of weights and thresholds. The agreement and disagreement weights for each feature indicate the importance of the feature to the quality of record linkage. This research uses differential evolution to globally optimise this vector of weights and thresholds. There is inevitably some uncertainty associated with the measurement of the quality of record linkage, and consequently with the optimum values for the weights and thresholds; this research not only measures the quality of record linkage but also identifies robust techniques for the estimation of its uncertainty.

Machine Learning Techniques and Stochastic Modeling in Mathematical Oncology

The cancer stem cell hypothesis claims that tumor growth and progression are driven by a (typically) small niche of the total cancer cell population called cancer stem cells (CSCs). These CSCs can go through symmetric or asymmetric divisions to differentiate into specialised, progenitor cells or reproduce new CSCs. While it was once held that this differentiation pathway was unidirectional, recent research has demonstrated that differenti- ated cells are more plastic than initially considered. In particular, differentiated cells can de-differentiate and recover their stem-like capacity. Two recent papers have considered how this rate of plasticity affects the evolutionary dynamic of an invasive, malignant population of stem cells and differentiated cells into existing tissue [64, 109]. These papers arrive at seemingly opposing conclusions, one claiming that increased plasticity results in increased invasive potential, and the other that increased plasticity decreases invasive potential. Here, we show that what is most important, when determining the effect on invasive potential, is how one distributes this increased plasticity between the compartments of resident and mutant-type cells. We also demonstrate how these results vary, producing non-monotone fixation probability curves, as inter-compartmental plasticity changes when differentiated cell compartments are allowed to continue proliferating, highlighting a fundamental dif- ference between the two models. We conclude by demonstrating the stability of these qualitative results over various parameter ranges. Imaging flow cytometry is a tool that uses the high-throughput capabilities of conven- tional flow cytometry for the purposes of producing single cell images. We demonstrate the label free prediction of mitotic cell cycle phases in Jurkat cells by utilizing brightfield and darkfield images from an imaging flow cytometer. The method is a non destructive method that relies upon images only and does not introduce (potentially confounding) dies or biomarkers to the cell cycles. By utilizing deep convolutional neural networks regularized by generated, synthetic images in the presence of severe class imbalance we are able to produce an estimator that outperforms the previous state of the art on the dataset by 10-15%. The in-silico development of a chemotherapeutic dosing schedule for treating cancer relies upon a parameterization of a particular tumour growth model to describe the dynamics of the cancer in response to the dose of the drug. In practice, it is often prohibitively difficult to ensure the validity of patient-specific parameterizations of these models for any particular patient. As a result, sensitivities to these particular parameters can result in therapeutic dosing schedules that are optimal in principle not performing well on particular patients. In this study, we demonstrate that chemotherapeutic dosing strategies learned via reinforcement learning methods are more robust to perturbations in patient-specific parameter values than those learned via classical optimal control methods. By training a reinforcement learning agent on mean-value parameters and allowing the agent periodic access to a more easily measurable metric, relative bone marrow density, for the purpose of optimizing dose schedule while reducing drug toxicity, we are able to develop drug dosing schedules that outperform schedules learned via classical optimal control methods, even when such methods are allowed to leverage the same bone marrow measurements

Cell fault management using machine learning techniques

This paper surveys the literature relating to the application of machine learning to fault management in cellular networks from an operational perspective. We summarise the main issues as 5G networks evolve, and their implications for fault management. We describe the relevant machine learning techniques through to deep learning, and survey the progress which has been made in their application, based on the building blocks of a typical fault management system. We review recent work to develop the abilities of deep learning systems to explain and justify their recommendations to network operators. We discuss forthcoming changes in network architecture which are likely to impact fault management and offer a vision of how fault management systems can exploit deep learning in the future. We identify a series of research topics for further study in order to achieve this

Ensembles of Pruned Deep Neural Networks for Accurate and Privacy Preservation in IoT Applications

The emergence of the AIoT (Artificial Intelligence of Things) represents the powerful convergence of Artificial Intelligence (AI) with the expansive realm of the Internet of Things (IoT). By integrating AI algorithms with the vast network of interconnected IoT devices, we open new doors for intelligent decision-making and edge data analysis, transforming various domains from healthcare and transportation to agriculture and smart cities. However, this integration raises pivotal questions: How can we ensure deep learning models are aptly compressed and quantised to operate seamlessly on devices constrained by computational resources, without compromising accuracy? How can these models be effectively tailored to cope with the challenges of statistical heterogeneity and the uneven distribution of class labels inherent in IoT applications? Furthermore, in an age where data is a currency, how do we uphold the sanctity of privacy for the sensitive data that IoT devices incessantly generate while also ensuring the unhampered deployment of these advanced deep learning models? Addressing these intricate challenges forms the crux of this thesis, with its contributions delineated as follows: Ensyth: A novel approach designed to synthesise pruned ensembles of deep learning models, which not only makes optimal use of limited IoT resources but also ensures a notable boost in predictability. Experimental evidence gathered from CIFAR-10, CIFAR-5, and MNIST-FASHION datasets solidify its merit, especially given its capacity to achieve high predictability. MicroNets: Venturing into the realms of efficiency, this is a multi-phase pruning pipeline that fuses the principles of weight pruning, channel pruning. Its objective is clear: foster efficient deep ensemble learning, specially crafted for IoT devices. Benchmark tests conducted on CIFAR-10 and CIFAR-100 datasets demonstrate its prowess, highlighting a compression ratio of nearly 92%, with these pruned ensembles surpassing the accuracy metrics set by conventional models. FedNets: Recognising the challenges of statistical heterogeneity in federated learning and the ever-growing concerns of data privacy, this innovative federated learning framework is introduced. It facilitates edge devices in their collaborative quest to train ensembles of pruned deep neural networks. More than just training, it ensures data privacy remains uncompromised. Evaluations conducted on the Federated CIFAR-100 dataset offer a testament to its efficacy. In this thesis, substantial contributions have been made to the AIoT application domain. Ensyth, MicroNets, and FedNets collaboratively tackle the challenges of efficiency, accuracy, statistical heterogeneity arising from distributed class labels, and privacy concerns inherent in deploying AI applications on IoT devices. The experimental results underscore the effectiveness of these approaches, paving the way for their practical implementation in real-world scenarios. By offering an integrated solution that satisfies multiple key requirements simultaneously, this research brings us closer to the realisation of effective and privacy-preserved AIoT systems