304 research outputs found
A clinical decision support system for detecting and mitigating potentially inappropriate medications
Background: Medication errors are a leading cause of preventable harm to patients. In older adults, the impact of ageing on the therapeutic effectiveness and safety of drugs is a significant concern, especially for those over 65. Consequently, certain medications called Potentially Inappropriate Medications (PIMs) can be dangerous in the elderly and should be avoided. Tackling PIMs by health professionals and patients can be time-consuming and error-prone, as the criteria underlying the definition of PIMs are complex and subject to frequent updates. Moreover, the criteria are not available in a representation that health systems can interpret and reason with directly.
Objectives: This thesis aims to demonstrate the feasibility of using an ontology/rule-based approach in a clinical knowledge base to identify potentially inappropriate medication(PIM). In addition, how constraint solvers can be used effectively to suggest alternative medications and administration schedules to solve or minimise PIM undesirable side effects.
Methodology: To address these objectives, we propose a novel integrated approach using formal rules to represent the PIMs criteria and inference engines to perform the reasoning presented in the context of a Clinical Decision Support System (CDSS). The approach aims to detect, solve, or minimise undesirable side-effects of PIMs through an ontology (knowledge base) and inference engines incorporating multiple reasoning approaches.
Contributions: The main contribution lies in the framework to formalise PIMs, including the steps required to define guideline requisites to create inference rules to detect and propose alternative drugs to inappropriate medications. No formalisation of the selected guideline (Beers Criteria) can be found in the literature, and hence, this thesis provides a novel ontology for it. Moreover, our process of minimising undesirable side effects offers a novel approach that enhances and optimises the drug rescheduling process, providing a more accurate way to minimise the effect of drug interactions in clinical practice
“So what if ChatGPT wrote it?” Multidisciplinary perspectives on opportunities, challenges and implications of generative conversational AI for research, practice and policy
Transformative artificially intelligent tools, such as ChatGPT, designed to generate sophisticated text indistinguishable from that produced by a human, are applicable across a wide range of contexts. The technology presents opportunities as well as, often ethical and legal, challenges, and has the potential for both positive and negative impacts for organisations, society, and individuals. Offering multi-disciplinary insight into some of these, this article brings together 43 contributions from experts in fields such as computer science, marketing, information systems, education, policy, hospitality and tourism, management, publishing, and nursing. The contributors acknowledge ChatGPT’s capabilities to enhance productivity and suggest that it is likely to offer significant gains in the banking, hospitality and tourism, and information technology industries, and enhance business activities, such as management and marketing. Nevertheless, they also consider its limitations, disruptions to practices, threats to privacy and security, and consequences of biases, misuse, and misinformation. However, opinion is split on whether ChatGPT’s use should be restricted or legislated. Drawing on these contributions, the article identifies questions requiring further research across three thematic areas: knowledge, transparency, and ethics; digital transformation of organisations and societies; and teaching, learning, and scholarly research. The avenues for further research include: identifying skills, resources, and capabilities needed to handle generative AI; examining biases of generative AI attributable to training datasets and processes; exploring business and societal contexts best suited for generative AI implementation; determining optimal combinations of human and generative AI for various tasks; identifying ways to assess accuracy of text produced by generative AI; and uncovering the ethical and legal issues in using generative AI across different contexts
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Sonic heritage: listening to the past
History is so often told through objects, images and photographs, but the potential of sounds to reveal place and space is often neglected. Our research project ‘Sonic Palimpsest’1 explores the potential of sound to evoke impressions and new understandings of the past, to embrace the sonic as a tool to understand what was, in a way that can complement and add to our predominant visual understandings. Our work includes the expansion of the Oral History archives held at Chatham Dockyard to include women’s voices and experiences, and the creation of sonic works to engage the public with their heritage. Our research highlights the social and cultural value of oral history and field recordings in the transmission of knowledge to both researchers and the public. Together these recordings document how buildings and spaces within the dockyard were used and experienced by those who worked there. We can begin to understand the social and cultural roles of these buildings within the community, both past and present
Application of knowledge management principles to support maintenance strategies in healthcare organisations
Healthcare is a vital service that touches people's lives on a daily basis by providing treatment and
resolving patients' health problems through the staff. Human lives are ultimately dependent on the skilled
hands of the staff and those who manage the infrastructure that supports the daily operations of the
service, making it a compelling reason for a dedicated research study. However, the UK healthcare sector
is undergoing rapid changes, driven by rising costs, technological advancements, changing patient
expectations, and increasing pressure to deliver sustainable healthcare. With the global rise in healthcare
challenges, the need for sustainable healthcare delivery has become imperative. Sustainable healthcare
delivery requires the integration of various practices that enhance the efficiency and effectiveness of
healthcare infrastructural assets. One critical area that requires attention is the management of
healthcare facilities.
Healthcare facilitiesis considered one of the core elements in the delivery of effective healthcare services,
as shortcomings in the provision of facilities management (FM) services in hospitals may have much more
drastic negative effects than in any other general forms of buildings. An essential element in healthcare
FM is linked to the relationship between action and knowledge. With a full sense of understanding of
infrastructural assets, it is possible to improve, manage and make buildings suitable to the needs of users
and to ensure the functionality of the structure and processes.
The premise of FM is that an organisation's effectiveness and efficiency are linked to the physical
environment in which it operates and that improving the environment can result in direct benefits in
operational performance. The goal of healthcare FM is to support the achievement of organisational
mission and goals by designing and managing space and infrastructural assets in the best combination of
suitability, efficiency, and cost. In operational terms, performance refers to how well a building
contributes to fulfilling its intended functions.
Therefore, comprehensive deployment of efficient FM approaches is essential for ensuring quality
healthcare provision while positively impacting overall patient experiences. In this regard, incorporating
knowledge management (KM) principles into hospitals' FM processes contributes significantly to ensuring
sustainable healthcare provision and enhancement of patient experiences. Organisations implementing
KM principles are better positioned to navigate the constantly evolving business ecosystem easily.
Furthermore, KM is vital in processes and service improvement, strategic decision-making, and
organisational adaptation and renewal.
In this regard, KM principles can be applied to improve hospital FM, thereby ensuring sustainable
healthcare delivery. Knowledge management assumes that organisations that manage their
organisational and individual knowledge more effectively will be able to cope more successfully with the challenges of the new business ecosystem. There is also the argument that KM plays a crucial role in
improving processes and services, strategic decision-making, and adapting and renewing an organisation.
The goal of KM is to aid action – providing "a knowledge pull" rather than the information overload most
people experience in healthcare FM. Other motivations for seeking better KM in healthcare FM include
patient safety, evidence-based care, and cost efficiency as the dominant drivers. The most evidence exists
for the success of such approaches at knowledge bottlenecks, such as infection prevention and control,
working safely, compliances, automated systems and reminders, and recall based on best practices. The
ability to cultivate, nurture and maximise knowledge at multiple levels and in multiple contexts is one of
the most significant challenges for those responsible for KM. However, despite the potential benefits,
applying KM principles in hospital facilities is still limited. There is a lack of understanding of how KM can
be effectively applied in this context, and few studies have explored the potential challenges and
opportunities associated with implementing KM principles in hospitals facilities for sustainable healthcare
delivery.
This study explores applying KM principles to support maintenance strategies in healthcare organisations.
The study also explores the challenges and opportunities, for healthcare organisations and FM
practitioners, in operationalising a framework which draws the interconnectedness between healthcare.
The study begins by defining healthcare FM and its importance in the healthcare industry. It then discusses
the concept of KM and the different types of knowledge that are relevant in the healthcare FM sector.
The study also examines the challenges that healthcare FM face in managing knowledge and how the
application of KM principles can help to overcome these challenges. The study then explores the different
KM strategies that can be applied in healthcare FM. The KM benefits include improved patient outcomes,
reduced costs, increased efficiency, and enhanced collaboration among healthcare professionals.
Additionally, issues like creating a culture of innovation, technology, and benchmarking are considered.
In addition, a framework that integrates the essential concepts of KM in healthcare FM will be presented
and discussed.
The field of KM is introduced as a complex adaptive system with numerous possibilities and challenges.
In this context, and in consideration of healthcare FM, five objectives have been formulated to achieve
the research aim. As part of the research, a number of objectives will be evaluated, including appraising
the concept of KM and how knowledge is created, stored, transferred, and utilised in healthcare FM,
evaluating the impact of organisational structure on job satisfaction as well as exploring how cultural
differences impact knowledge sharing and performance in healthcare FM organisations.
This study uses a combination of qualitative methods, such as meetings, observations, document analysis
(internal and external), and semi-structured interviews, to discover the subjective experiences of
healthcare FM employees and to understand the phenomenon within a real-world context and attitudes of healthcare FM as the data collection method, using open questions to allow probing where appropriate
and facilitating KM development in the delivery and practice of healthcare FM.
The study describes the research methodology using the theoretical concept of the "research onion". The
qualitative research was conducted in the NHS acute and non-acute hospitals in Northwest England.
Findings from the research study revealed that while the concept of KM has grown significantly in recent
years, KM in healthcare FM has received little or no attention. The target population was fifty (five FM
directors, five academics, five industry experts, ten managers, ten supervisors, five team leaders and ten
operatives). These seven groups were purposively selected as the target population because they play a
crucial role in KM enhancement in healthcare FM. Face-to-face interviews were conducted with all
participants based on their pre-determined availability. Out of the 50-target population, only 25 were
successfully interviewed to the point of saturation. Data collected from the interview were coded and
analysed using NVivo to identify themes and patterns related to KM in healthcare FM.
The study is divided into eight major sections. First, it discusses literature findings regarding healthcare
FM and KM, including underlying trends in FM, KM in general, and KM in healthcare FM. Second, the
research establishes the study's methodology, introducing the five research objectives, questions and
hypothesis. The chapter introduces the literature on methodology elements, including philosophical views
and inquiry strategies. The interview and data analysis look at the feedback from the interviews. Lastly, a
conclusion and recommendation summarise the research objectives and suggest further research.
Overall, this study highlights the importance of KM in healthcare FM and provides insights for healthcare
FM directors, managers, supervisors, academia, researchers and operatives on effectively leveraging
knowledge to improve patient care and organisational effectiveness
Metaverse. Old urban issues in new virtual cities
Recent years have seen the arise of some early attempts to build virtual cities,
utopias or affective dystopias in an embodied Internet, which in some respects appear to
be the ultimate expression of the neoliberal city paradigma (even if virtual). Although
there is an extensive disciplinary literature on the relationship between planning and
virtual or augmented reality linked mainly to the gaming industry, this often avoids design
and value issues. The observation of some of these early experiences - Decentraland,
Minecraft, Liberland Metaverse, to name a few - poses important questions and problems
that are gradually becoming inescapable for designers and urban planners, and allows
us to make some partial considerations on the risks and potentialities of these early virtual
cities
LIPIcs, Volume 261, ICALP 2023, Complete Volume
LIPIcs, Volume 261, ICALP 2023, Complete Volum
Semiring Provenance for Lightweight Description Logics
We investigate semiring provenance--a successful framework originally defined
in the relational database setting--for description logics. In this context,
the ontology axioms are annotated with elements of a commutative semiring and
these annotations are propagated to the ontology consequences in a way that
reflects how they are derived. We define a provenance semantics for a language
that encompasses several lightweight description logics and show its
relationships with semantics that have been defined for ontologies annotated
with a specific kind of annotation (such as fuzzy degrees). We show that under
some restrictions on the semiring, the semantics satisfies desirable properties
(such as extending the semiring provenance defined for databases). We then
focus on the well-known why-provenance, which allows to compute the semiring
provenance for every additively and multiplicatively idempotent commutative
semiring, and for which we study the complexity of problems related to the
provenance of an axiom or a conjunctive query answer. Finally, we consider two
more restricted cases which correspond to the so-called positive Boolean
provenance and lineage in the database setting. For these cases, we exhibit
relationships with well-known notions related to explanations in description
logics and complete our complexity analysis. As a side contribution, we provide
conditions on an ELHI_bot ontology that guarantee tractable reasoning.Comment: Paper currently under review. 102 page
“So what if ChatGPT wrote it?” Multidisciplinary perspectives on opportunities, challenges and implications of generative conversational AI for research, practice and policy
Transformative artificially intelligent tools, such as ChatGPT, designed to generate sophisticated text indistinguishable from that produced by a human, are applicable across a wide range of contexts. The technology presents opportunities as well as, often ethical and legal, challenges, and has the potential for both positive and negative impacts for organisations, society, and individuals. Offering multi-disciplinary insight into some of these, this article brings together 43 contributions from experts in fields such as computer science, marketing, information systems, education, policy, hospitality and tourism, management, publishing, and nursing. The contributors acknowledge ChatGPT's capabilities to enhance productivity and suggest that it is likely to offer significant gains in the banking, hospitality and tourism, and information technology industries, and enhance business activities, such as management and marketing. Nevertheless, they also consider its limitations, disruptions to practices, threats to privacy and security, and consequences of biases, misuse, and misinformation. However, opinion is split on whether ChatGPT's use should be restricted or legislated. Drawing on these contributions, the article identifies questions requiring further research across three thematic areas: knowledge, transparency, and ethics; digital transformation of organisations and societies; and teaching, learning, and scholarly research. The avenues for further research include: identifying skills, resources, and capabilities needed to handle generative AI; examining biases of generative AI attributable to training datasets and processes; exploring business and societal contexts best suited for generative AI implementation; determining optimal combinations of human and generative AI for various tasks; identifying ways to assess accuracy of text produced by generative AI; and uncovering the ethical and legal issues in using generative AI across different contexts
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