Searching Ontologies Based on Content: Experiments in the Biomedical Domain

As more ontologies become publicly available, finding the "right" ontologies becomes much harder. In this paper, we address the problem of ontology search: finding a collection of ontologies from an ontology repository that are relevant to the user's query. In particular, we look at the case when users search for ontologies relevant to a particular topic (e.g., an ontology about anatomy). Ontologies that are most relevant to such query often do not have the query term in the names of their concepts (e.g., the Foundational Model of Anatomy ontology does not have the term "anatomy" in any of its concepts' names). Thus, we present a new ontology-search technique that helps users in these types of searches. When looking for ontologies on a particular topic (e.g., anatomy), we retrieve from the Web a collection of terms that represent the given domain (e.g., terms such as body, brain, skin, etc. for anatomy). We then use these terms to expand the user query. We evaluate our algorithm on queries for topics in the biomedical domain against a repository of biomedical ontologies. We use the results obtained from experts in the biomedical-ontology domain as the gold standard. Our experiments demonstrate that using our method for query expansion improves retrieval results by a 113%, compared to the tools that search only for the user query terms and consider only class and property names (like Swoogle). We show 43% improvement for the case where not only class and property names but also property values are taken into account

Applications of the ACGT Master Ontology on Cancer

In this paper we present applications of the ACGT Master Ontology (MO) which is a new terminology resource for a transnational network providing data exchange in oncology, emphasizing the integration of both clinical and molecular data. The development of a new ontology was necessary due to problems with existing biomedical ontologies in oncology. The ACGT MO is a test case for the application of best practices in ontology development. This paper provides an overview of the application of the ontology within the ACGT project thus far

Semantic-based decision support for remote care of dementia patients

This paper investigates the challenges in developing a semantic-based Dementia Care Decision Support System based on the non-intrusive monitoring of the patient's behaviour. Semantic-based approaches are well suited for modelling context-aware scenarios similar to Dementia care systems, where the patient's dynamic behaviour observations (occupants movement, equipment use) need to be analysed against the semantic knowledge about the patient's condition (illness history, medical advice, known symptoms) in an integrated knowledgebase. However, our research findings establish that the ability of semantic technologies to reason upon the complex interrelated events emanating from the behaviour monitoring sensors to infer knowledge assisting medical advice represents a major challenge. We attempt to address this problem by introducing a new approach that relies on propositional calculus modelling to segregate complex events that are amenable for semantic reasoning from events that require pre-processing outside the semantic engine before they can be reasoned upon. The event pre-processing activity also controls the timing of triggering the reasoning process in order to further improve the efficiency of the inference process. Using regression analysis, we evaluate the response-time as the number of monitored patients increases and conclude that the incurred overhead on the response time of the prototype decision support systems remains tolerable

Ontologies on the semantic web

As an informational technology, the World Wide Web has enjoyed spectacular success. In just ten years it has transformed the way information is produced, stored, and shared in arenas as diverse as shopping, family photo albums, and high-level academic research. The “Semantic Web” was touted by its developers as equally revolutionary but has not yet achieved anything like the Web’s exponential uptake. This 17 000 word survey article explores why this might be so, from a perspective that bridges both philosophy and IT