Dynamical criticality: overview and open questions

Systems that exhibit complex behaviours are often found in a particular dynamical condition, poised between order and disorder. This observation is at the core of the so-called criticality hypothesis, which states that systems in a dynamical regime between order and disorder attain the highest level of computational capabilities and achieve an optimal trade-off between robustness and flexibility. Recent results in cellular and evolutionary biology, neuroscience and computer science have revitalised the interest in the criticality hypothesis, emphasising its role as a viable candidate general law in adaptive complex systems. This paper provides an overview of the works on dynamical criticality that are - to the best of our knowledge - particularly relevant for the criticality hypothesis. The authors review the main contributions concerning dynamics and information processing at the edge of chaos, and illustrate the main achievements in the study of critical dynamics in biological systems. Finally, the authors discuss open questions and propose an agenda for future work

What is Robotics: Why Do We Need It and How Can We Get It?

Robotics is an emerging synthetic science concerned with programming work. Robot technologies are quickly advancing beyond the insights of the existing science. More secure intellectual foundations will be required to achieve better, more reliable and safer capabilities as their penetration into society deepens. Presently missing foundations include the identification of fundamental physical limits, the development of new dynamical systems theory and the invention of physically grounded programming languages. The new discipline needs a departmental home in the universities which it can justify both intellectually and by its capacity to attract new diverse populations inspired by the age old human fascination with robots. For more information: Kod*la

This Week's Finds in Mathematical Physics (1-50)

These are the first 50 issues of This Week's Finds of Mathematical Physics, from January 19, 1993 to March 12, 1995. These issues focus on quantum gravity, topological quantum field theory, knot theory, and applications of $n$-categories to these subjects. However, there are also digressions into Lie algebras, elliptic curves, linear logic and other subjects. They were typeset in 2020 by Tim Hosgood. If you see typos or other problems please report them. (I already know the cover page looks weird).Comment: 242 page

Inquiries into words, constraints and contexts : Festschrift in the honour of Kimmo Koskenniemi on his 60th birthday

Peer reviewe

Translational Oncogenomics and Human Cancer Interactome Networks

An overview of translational, human oncogenomics, transcriptomics and cancer interactomic networks is presented together with basic concepts and potential, new applications to Oncology and Integrative Cancer Biology. Novel translational oncogenomics research is rapidly expanding through the application of advanced technology, research findings and computational tools/models to both pharmaceutical and clinical problems. A self-contained presentation is adopted that covers both fundamental concepts and the most recent biomedical, as well as clinical, applications. Sample analyses in recent clinical studies have shown that gene expression data can be employed to distinguish between tumor types as well as to predict outcomes. Potentially important applications of such results are individualized human cancer therapies or, in general, ‘personalized medicine’. Several cancer detection techniques are currently under development both in the direction of improved detection sensitivity and increased time resolution of cellular events, with the limits of single molecule detection and picosecond time resolution already reached. The urgency for the complete mapping of a human cancer interactome with the help of such novel, high-efficiency / low-cost and ultra-sensitive techniques is also pointed out