21,150 research outputs found
Hierarchical Bayesian sparse image reconstruction with application to MRFM
This paper presents a hierarchical Bayesian model to reconstruct sparse
images when the observations are obtained from linear transformations and
corrupted by an additive white Gaussian noise. Our hierarchical Bayes model is
well suited to such naturally sparse image applications as it seamlessly
accounts for properties such as sparsity and positivity of the image via
appropriate Bayes priors. We propose a prior that is based on a weighted
mixture of a positive exponential distribution and a mass at zero. The prior
has hyperparameters that are tuned automatically by marginalization over the
hierarchical Bayesian model. To overcome the complexity of the posterior
distribution, a Gibbs sampling strategy is proposed. The Gibbs samples can be
used to estimate the image to be recovered, e.g. by maximizing the estimated
posterior distribution. In our fully Bayesian approach the posteriors of all
the parameters are available. Thus our algorithm provides more information than
other previously proposed sparse reconstruction methods that only give a point
estimate. The performance of our hierarchical Bayesian sparse reconstruction
method is illustrated on synthetic and real data collected from a tobacco virus
sample using a prototype MRFM instrument.Comment: v2: final version; IEEE Trans. Image Processing, 200
Multispectral data restoration study
A digital resampling technique for LANDSAT data is reported that incorporates a deconvolution concept to minimize spatial and radiometric degradation of data during resampling for geometric correction. A quantitative comparison of cubic convolution and digital restoration methods establishes the latter as the superior technique
Sparsity driven ultrasound imaging
An image formation framework for ultrasound imaging from synthetic transducer arrays based on sparsity-driven regularization functionals using single-frequency Fourier domain data is proposed. The framework involves the use of a physics-based forward model of the ultrasound observation process, the formulation of image formation as the solution of an associated optimization problem, and the solution of that problem through efficient numerical algorithms. The sparsity-driven, model-based approach estimates a complex-valued reflectivity field and preserves physical features in the scene while suppressing spurious artifacts. It also provides robust reconstructions in the case of sparse and reduced observation apertures. The effectiveness of the proposed imaging strategy is demonstrated using experimental data
Simple method for sub-diffraction resolution imaging of cellular structures on standard confocal microscopes by three-photon absorption of quantum dots
This study describes a simple technique that improves a recently developed 3D sub-diffraction imaging method based on three-photon absorption of commercially available quantum dots. The method combines imaging of biological samples via tri-exciton generation in quantum dots with deconvolution and spectral multiplexing, resulting in a novel approach for multi-color imaging of even thick biological samples at a 1.4 to 1.9-fold better spatial resolution. This approach is realized on a conventional confocal microscope equipped with standard continuous-wave lasers. We demonstrate the potential of multi-color tri-exciton imaging of quantum dots combined with deconvolution on viral vesicles in lentivirally transduced cells as well as intermediate filaments in three-dimensional clusters of mouse-derived neural stem cells (neurospheres) and dense microtubuli arrays in myotubes formed by stacks of differentiated C2C12 myoblasts
SSTRED: A data-processing and metadata-generating pipeline for CHROMIS and CRISP
We present a data pipeline for the newly installed SST/CHROMIS imaging
spectrometer, as well as for the older SST/CRISP spectropolarimeter. The aim is
to provide observers with a user-friendly data pipeline, that delivers
science-ready data with the metadata needed for archival. We generalized the
CRISPRED data pipeline for multiple instruments and added metadata according to
recommendations worked out as part of the SOLARNET project. We made
improvements to several steps in the pipeline, including the MOMFBD image
restoration. A part of that is a new fork of the MOMFBD program called REDUX,
with several new features that are needed in the new pipeline. The CRISPEX data
viewer has been updated to accommodate data cubes stored in this format. The
pipeline code, as well as REDUX and CRISPEX are all freely available through
git repositories or web download. We derive expressions for combining
statistics of individual frames into statistics for a set of frames. We define
a new extension to the World Coordinate System, that allow us to specify cavity
errors as distortions to the spectral coordinate.Comment: Draf
The residual STL volume as a metric to evaluate accuracy and reproducibility of anatomic models for 3D printing: application in the validation of 3D-printable models of maxillofacial bone from reduced radiation dose CT images.
BackgroundThe effects of reduced radiation dose CT for the generation of maxillofacial bone STL models for 3D printing is currently unknown. Images of two full-face transplantation patients scanned with non-contrast 320-detector row CT were reconstructed at fractions of the acquisition radiation dose using noise simulation software and both filtered back-projection (FBP) and Adaptive Iterative Dose Reduction 3D (AIDR3D). The maxillofacial bone STL model segmented with thresholding from AIDR3D images at 100 % dose was considered the reference. For all other dose/reconstruction method combinations, a "residual STL volume" was calculated as the topologic subtraction of the STL model derived from that dataset from the reference and correlated to radiation dose.ResultsThe residual volume decreased with increasing radiation dose and was lower for AIDR3D compared to FBP reconstructions at all doses. As a fraction of the reference STL volume, the residual volume decreased from 2.9 % (20 % dose) to 1.4 % (50 % dose) in patient 1, and from 4.1 % to 1.9 %, respectively in patient 2 for AIDR3D reconstructions. For FBP reconstructions it decreased from 3.3 % (20 % dose) to 1.0 % (100 % dose) in patient 1, and from 5.5 % to 1.6 %, respectively in patient 2. Its morphology resembled a thin shell on the osseous surface with average thickness <0.1 mm.ConclusionThe residual volume, a topological difference metric of STL models of tissue depicted in DICOM images supports that reduction of CT dose by up to 80 % of the clinical acquisition in conjunction with iterative reconstruction yields maxillofacial bone models accurate for 3D printing
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