Control of a train of high purity distillation columns for efficient production of 13C isotopes

It is well-known that high-purity distillation columns are difficult to control due to their ill-conditioned and strongly nonlinear behaviour. The fact that these processes are operated over a wide range of feed compositions and flow rates makes the control design even more challenging. This paper proposes the most suitable control strategies applicable to a series of cascaded distillation column processes. The conditions for control and input-output relations are discusssed in view of the global control strategy. The increase in complexity with increased number of series cascaded distillation column processes is tackled. Uncertainty in the model parameters is discussed with respect to the dynamics of the global train distillation process. The main outcome of this work is insight into the possible control methodologies for this particular class of distillation processes

Multi-objective genetic optimisation for self-organising fuzzy logic control

This is the post-print version of the article. The official published version can be accessed from the link below.A multi-objective genetic algorithm is developed for the purpose of optimizing the rule-base of a Self-Organising Fuzzy Logic Control algorithm (SOFLC). The tuning of the SOFLC optimization is based on selection of the best shaped performance index for modifying the rule-base on-line. A comparative study is conducted between various methods of multi-objective genetic optimisation using the SOFLC algorithm on the muscle relaxant anaesthesia system, which includes a severe non-linearity, varying dynamics and time-delay

Robustness and performance trade-offs in control design for flexible structures

Linear control design models for flexible structures are only an approximation to the “real” structural system. There are always modeling errors or uncertainty present. Descriptions of these uncertainties determine the trade-off between achievable performance and robustness of the control design. In this paper it is shown that a controller synthesized for a plant model which is not described accurately by the nominal and uncertainty models may be unstable or exhibit poor performance when implemented on the actual system. In contrast, accurate structured uncertainty descriptions lead to controllers which achieve high performance when implemented on the experimental facility. It is also shown that similar performance, theoretically and experimentally, is obtained for a surprisingly wide range of uncertain levels in the design model. This suggests that while it is important to have reasonable structured uncertainty models, it may not always be necessary to pin down precise levels (i.e., weights) of uncertainty. Experimental results are presented which substantiate these conclusions

Computer-aided design and distributed system technology development for large space structures

Proposed large space structures have many characteristics that make them difficult to analyze and control. They are highly flexible, with components mathematically modeled by partial differential equations or very large systems of ordinary differential equations. They have many resonant frequencies, typically low and closely spaced. Natural damping may be low and/or improperly modeled. Coupled with stringent operational requirements of orientation, shape control, and vibration suppression, and the inability to perform adequate ground testing, these characteristics present an unconventional identification and control design problem to the systems theorist. Some of the research underway within Langley's Spacecraft Control Branch, Guidance and Control Division aimed at developing theory and algorithms to treat large space structures systems identification and control problems is described. The research areas to be considered are computer-aided design algorithms, and systems identification and control of distributed systems

Explanation and Elaboration Document for the STROBE-Vet Statement: Strengthening the Reporting of Observational Studies in Epidemiology—Veterinary Extension

The STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) statement was first published in 2007 and again in 2014. The purpose of the original STROBE was to provide guidance for authors, reviewers and editors to improve the comprehensiveness of reporting; however, STROBE has a unique focus on observational studies. Although much of the guidance provided by the original STROBE document is directly applicable, it was deemed useful to map those statements to veterinary concepts, provide veterinary examples and highlight unique aspects of reporting in veterinary observational studies. Here, we present the examples and explanations for the checklist items included in the STROBE-Vet Statement. Thus, this is a companion document to the STROBE-Vet Statement Methods and process document, which describes the checklist and how it was developed

Addendum to Informatics for Health 2017: Advancing both science and practice

This article presents presentation and poster abstracts that were mistakenly omitted from the original publication

Robust integrated autopilot/autothrottle design using constrained parameter optimization

A multivariable control design method based on constrained parameter optimization was applied to the design of a multiloop aircraft flight control system. Specifically, the design method is applied to the following: (1) direct synthesis of a multivariable 'inner-loop' feedback control system based on total energy control principles; (2) synthesis of speed/altitude-hold designs as 'outer-loop' feedback/feedforward control systems around the above inner loop; and (3) direct synthesis of a combined 'inner-loop' and 'outer-loop' multivariable control system. The design procedure offers a direct and structured approach for the determination of a set of controller gains that meet design specifications in closed-loop stability, command tracking performance, disturbance rejection, and limits on control activities. The presented approach may be applied to a broader class of multiloop flight control systems. Direct tradeoffs between many real design goals are rendered systematic by this method following careful problem formulation of the design objectives and constraints. Performance characteristics of the optimization design were improved over the current autopilot design on the B737-100 Transport Research Vehicle (TSRV) at the landing approach and cruise flight conditions; particularly in the areas of closed-loop damping, command responses, and control activity in the presence of turbulence