136,783 research outputs found
Collective Charge Fluctuations in Single-Electron Processes on Nano-Networks
Using numerical modeling we study emergence of structure and
structure-related nonlinear conduction properties in the self-assembled
nanoparticle films. Particularly, we show how different nanoparticle networks
emerge within assembly processes with molecular bio-recognition binding. We
then simulate the charge transport under voltage bias via single-electron
tunnelings through the junctions between nanoparticles on such type of
networks. We show how the regular nanoparticle array and topologically
inhomogeneous nanonetworks affect the charge transport. We find long-range
correlations in the time series of charge fluctuation at individual
nanoparticles and of flow along the junctions within the network. These
correlations explain the occurrence of a large nonlinearity in the simulated
and experimentally measured current-voltage characteristics and non-Gaussian
fluctuations of the current at the electrode.Comment: 10 pages, 7 figure
Complex networks theory for analyzing metabolic networks
One of the main tasks of post-genomic informatics is to systematically
investigate all molecules and their interactions within a living cell so as to
understand how these molecules and the interactions between them relate to the
function of the organism, while networks are appropriate abstract description
of all kinds of interactions. In the past few years, great achievement has been
made in developing theory of complex networks for revealing the organizing
principles that govern the formation and evolution of various complex
biological, technological and social networks. This paper reviews the
accomplishments in constructing genome-based metabolic networks and describes
how the theory of complex networks is applied to analyze metabolic networks.Comment: 13 pages, 2 figure
Jamming in complex networks with degree correlation
We study the effects of the degree-degree correlations on the pressure
congestion J when we apply a dynamical process on scale free complex networks
using the gradient network approach. We find that the pressure congestion for
disassortative (assortative) networks is lower (bigger) than the one for
uncorrelated networks which allow us to affirm that disassortative networks
enhance transport through them. This result agree with the fact that many real
world transportation networks naturally evolve to this kind of correlation. We
explain our results showing that for the disassortative case the clusters in
the gradient network turn out to be as much elongated as possible, reducing the
pressure congestion J and observing the opposite behavior for the assortative
case. Finally we apply our model to real world networks, and the results agree
with our theoretical model
Near mean-field behavior in the generalized Burridge-Knopoff earthquake model with variable range stress transfer
Simple models of earthquake faults are important for understanding the
mechanisms for their observed behavior in nature, such as Gutenberg-Richter
scaling. Because of the importance of long-range interactions in an elastic
medium, we generalize the Burridge-Knopoff slider-block model to include
variable range stress transfer. We find that the Burridge-Knopoff model with
long-range stress transfer exhibits qualitatively different behavior than the
corresponding long-range cellular automata models and the usual
Burridge-Knopoff model with nearest-neighbor stress transfer, depending on how
quickly the friction force weakens with increasing velocity. Extensive
simulations of quasiperiodic characteristic events, mode-switching phenomena,
ergodicity, and waiting-time distributions are also discussed. Our results are
consistent with the existence of a mean-field critical point and have important
implications for our understanding of earthquakes and other driven dissipative
systems.Comment: 24 pages 12 figures, revised version for Phys. Rev.
Confined water in the low hydration regime
Molecular dynamics results on water confined in a silica pore in the low
hydration regime are presented. Strong layering effects are found due to the
hydrophilic character of the substrate. The local properties of water are
studied as function of both temperature and hydration level. The interaction of
the thin films of water with the silica atoms induces a strong distortion of
the hydrogen bond network. The residence time of the water molecules is
dependent on the distance from the surface. Its behavior shows a transition
from a brownian to a non-brownian regime approaching the substrate in agreement
with results found in studies of water at contact with globular proteins.Comment: 7 pages with 12 figures (RevTeX4). To be published on J. Chem. Phy
Vortex Lattice Melting in 2D Superconducting Networks and Films
We carry out MC studies of 2D superconducting networks, in an applied
magnetic field, for square and honeycomb geometries. We consider both dilute
systems (f=1/q) and systems near full frustration (f=1/2-1/q). For the dilute
case (which models a film as q->infinity), we find two transitions: at
T_c(f)~1/q there is a depinning transition from a pinned to a floating vortex
lattice; at T_m(f)~constant the floating vortex lattice melts into an isotropic
liquid. We analyze this melting according to the Kosterlitz- Thouless theory of
dislocation mediated melting, and find that the melting is weakly first order.
For the case near full frustration, the system can be described in terms of the
density of defects in an otherwise fully frustrated vortex pattern. We find
pinned solid, floating solid, and liquid defect phases, as well as a higher
sharp transition corresponding to the disordering of the fully frustrated
background.Comment: 55 pages, RevTex3.0, 25 figures (available by mail by contacting
[email protected]
Modeling of solvent flow effects in enzyme catalysis under physiological conditions
A stochastic model for the dynamics of enzymatic catalysis in explicit,
effective solvents under physiological conditions is presented.
Analytically-computed first passage time densities of a diffusing particle in a
spherical shell with absorbing boundaries are combined with densities obtained
from explicit simulation to obtain the overall probability density for the
total reaction cycle time of the enzymatic system. The method is used to
investigate the catalytic transfer of a phosphoryl group in a phosphoglycerate
kinase-ADP-bis phosphoglycerate system, one of the steps of glycolysis. The
direct simulation of the enzyme-substrate binding and reaction is carried out
using an elastic network model for the protein, and the solvent motions are
described by multiparticle collision dynamics, which incorporates hydrodynamic
flow effects. Systems where solvent-enzyme coupling occurs through explicit
intermolecular interactions, as well as systems where this coupling is taken
into account by including the protein and substrate in the multiparticle
collision step, are investigated and compared with simulations where
hydrodynamic coupling is absent. It is demonstrated that the flow of solvent
particles around the enzyme facilitates the large-scale hinge motion of the
enzyme with bound substrates, and has a significant impact on the shape of the
probability densities and average time scales of substrate binding for
substrates near the enzyme, the closure of the enzyme after binding, and the
overall time of completion of the cycle.Comment: 15 pages in double column forma
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