Mobile Ad Hoc Networks

Guiding readers through the basics of these rapidly emerging networks to more advanced concepts and future expectations, Mobile Ad hoc Networks: Current Status and Future Trends identifies and examines the most pressing research issues in Mobile Ad hoc Networks (MANETs). Containing the contributions of leading researchers, industry professionals, and academics, this forward-looking reference provides an authoritative perspective of the state of the art in MANETs. The book includes surveys of recent publications that investigate key areas of interest such as limited resources and the mobility of mobile nodes. It considers routing, multicast, energy, security, channel assignment, and ensuring quality of service. Also suitable as a text for graduate students, the book is organized into three sections: Fundamentals of MANET Modeling and Simulation—Describes how MANETs operate and perform through simulations and models Communication Protocols of MANETs—Presents cutting-edge research on key issues, including MAC layer issues and routing in high mobility Future Networks Inspired By MANETs—Tackles open research issues and emerging trends Illustrating the role MANETs are likely to play in future networks, this book supplies the foundation and insight you will need to make your own contributions to the field. It includes coverage of routing protocols, modeling and simulations tools, intelligent optimization techniques to multicriteria routing, security issues in FHAMIPv6, connecting moving smart objects to the Internet, underwater sensor networks, wireless mesh network architecture and protocols, adaptive routing provision using Bayesian inference, and adaptive flow control in transport layer using genetic algorithms

Malignant Mesothelioma

Malignant mesothelioma (MM) is a rare and aggressive cancer, related to chronic inflammation and oxidative stress caused mainly by exposure to asbestos. Although this mineral has been banned for decades in many countries, epidemiologists predict the MM epidemic will last past 2040, raising many concerns in public health given its late diagnosis, dismal prognosis, and lack of current efficient therapies.To deal with this situation, important breakthroughs have recently been made in the understanding of MM’s complex biology and the carcinogenic process of the different patterns of the disease. Examples of these include the development of new biomarkers and the deciphering of gene–environment interactions, molecular mechanisms of invasiveness, deregulated pathways, altered expression of miRNAs, DNA damage repair, or metabolic profile. From now on, MM’s aggressive and chemoresistant character appears linked to a polyclonal malignancy, and heterogeneity in molecular alterations.Given these improvements, new therapeutic targets are being explored to solve the double challenge faced by clinicians. The first is to reduce tumor development and its wasting consequences as soon as possible, without resistance and with limited toxicity. The second is to stimulate the recognition of tumor cells by the induction of a specific immune response. This Special Issue will highlight all these aspects