Nonparametric Covariate Adjustment for Receiver Operating Characteristic Curves

The accuracy of a diagnostic test is typically characterised using the receiver operating characteristic (ROC) curve. Summarising indexes such as the area under the ROC curve (AUC) are used to compare different tests as well as to measure the difference between two populations. Often additional information is available on some of the covariates which are known to influence the accuracy of such measures. We propose nonparametric methods for covariate adjustment of the AUC. Models with normal errors and non-normal errors are discussed and analysed separately. Nonparametric regression is used for estimating mean and variance functions in both scenarios. In the general noise case we propose a covariate-adjusted Mann-Whitney estimator for AUC estimation which effectively uses available data to construct working samples at any covariate value of interest and is computationally efficient for implementation. This provides a generalisation of the Mann-Whitney approach for comparing two populations by taking covariate effects into account. We derive asymptotic properties for the AUC estimators in both settings, including asymptotic normality, optimal strong uniform convergence rates and MSE consistency. The usefulness of the proposed methods is demonstrated through simulated and real data examples

Zero-variance zero-bias quantum Monte Carlo estimators of the spherically and system-averaged pair density

We construct improved quantum Monte Carlo estimators for the spherically- and system-averaged electron pair density (i.e. the probability density of finding two electrons separated by a relative distance u), also known as the spherically-averaged electron position intracule density I(u), using the general zero-variance zero-bias principle for observables, introduced by Assaraf and Caffarel. The calculation of I(u) is made vastly more efficient by replacing the average of the local delta-function operator by the average of a smooth non-local operator that has several orders of magnitude smaller variance. These new estimators also reduce the systematic error (or bias) of the intracule density due to the approximate trial wave function. Used in combination with the optimization of an increasing number of parameters in trial Jastrow-Slater wave functions, they allow one to obtain well converged correlated intracule densities for atoms and molecules. These ideas can be applied to calculating any pair-correlation function in classical or quantum Monte Carlo calculations.Comment: 13 pages, 9 figures, published versio

Advances in forecast evaluation

This paper surveys recent developments in the evaluation of point forecasts. Taking West's (2006) survey as a starting point, we briefly cover the state of the literature as of the time of West's writing. We then focus on recent developments, including advancements in the evaluation of forecasts at the population level (based on true, unknown model coefficients), the evaluation of forecasts in the finite sample (based on estimated model coefficients), and the evaluation of conditional versus unconditional forecasts. We present original results in a few subject areas: the optimization of power in determining the split of a sample into in-sample and out-of-sample portions; whether the accuracy of inference in evaluation of multi-step forecasts can be improved with judicious choice of HAC estimator (it can); and the extension of West's (1996) theory results for population-level, unconditional forecast evaluation to the case of conditional forecast evaluation.Forecasting

Advances in forecast evaluation

This paper surveys recent developments in the evaluation of point forecasts. Taking West’s (2006) survey as a starting point, we briefly cover the state of the literature as of the time of West’s writing. We then focus on recent developments, including advancements in the evaluation of forecasts at the population level (based on true, unknown model coefficients), the evaluation of forecasts in the finite sample (based on estimated model coefficients), and the evaluation of conditional versus unconditional forecasts. We present original results in a few subject areas: the optimization of power in determining the split of a sample into in-sample and out-of-sample portions; whether the accuracy of inference in evaluation of multistep forecasts can be improved with the judicious choice of HAC estimator (it can); and the extension of West’s (1996) theory results for population-level, unconditional forecast evaluation to the case of conditional forecast evaluation.Forecasting ; Time-series analysis

Revisiting the Gelman-Rubin Diagnostic

Gelman and Rubin's (1992) convergence diagnostic is one of the most popular methods for terminating a Markov chain Monte Carlo (MCMC) sampler. Since the seminal paper, researchers have developed sophisticated methods for estimating variance of Monte Carlo averages. We show that these estimators find immediate use in the Gelman-Rubin statistic, a connection not previously established in the literature. We incorporate these estimators to upgrade both the univariate and multivariate Gelman-Rubin statistics, leading to improved stability in MCMC termination time. An immediate advantage is that our new Gelman-Rubin statistic can be calculated for a single chain. In addition, we establish a one-to-one relationship between the Gelman-Rubin statistic and effective sample size. Leveraging this relationship, we develop a principled termination criterion for the Gelman-Rubin statistic. Finally, we demonstrate the utility of our improved diagnostic via examples