Photoacoustic computed tomography guided microrobots for targeted navigation in intestines in vivo

Tremendous progress in synthetic micro/nanomotors has been made for potential biomedical applications. However, existing micro/nanomotor platforms are inefficient for deep tissue imaging and motion control in vivo. Here, we present a photoacoustic computed tomography (PACT) guided investigation of micromotors in intestines in vivo. The micromotors enveloped in microcapsules exhibit efficient propulsion in various biofluids once released. PACT has visualized the migration of micromotor capsules toward the targeted regions in real time in vivo. The integration of the developed microrobotic system and PACT enables deep imaging and precise control of the micromotors in vivo

Foreign Object Detection and Quantification of Fat Content Using A Novel Multiplexing Electric Field Sensor

There is an ever growing need to ensure the quality of food and assess specific quality parameters in all the links of the food chain, ranging from processing, distribution and retail to preparing food. Various imaging and sensing technologies, including X-ray imaging, ultrasound, and near infrared reflectance spectroscopy have been applied to the problem. Cost and other constraints restrict the application of some of these technologies. In this study we test a novel Multiplexing Electric Field Sensor (MEFS), an approach that allows for a completely non-invasive and non-destructive testing approach. Our experiments demonstrate the reliable detection of certain foreign objects and provide evidence that this sensor technology has the capability of measuring fat content in minced meat. Given the fact that this technology can already be deployed at very low cost, low maintenance and in various different form factors, we conclude that this type of MEFS is an extremely promising technology for addressing specific food quality issues

Workshops at IMS2023

Lists future events that should be of interest to practitioners and researchers.Peer ReviewedPostprint (published version

A Dual-Beam Irradiation Facility for a Novel Hybrid Cancer Therapy

In this paper we present the main ideas and discuss both the feasibility and the conceptual design of a novel hybrid technique and equipment for an experimental cancer therapy based on the simultaneous and/or sequential application of two beams, namely a beam of neutrons and a CW (continuous wave) or intermittent sub-terahertz wave beam produced by a gyrotron for treatment of cancerous tumors. The main simulation tools for the development of the computer aided design (CAD) of the prospective experimental facility for clinical trials and study of such new medical technology are briefly reviewed. Some tasks for a further continuation of this feasibility analysis are formulated as well.Comment: 18 pages, 3 tables, 8 figures, 50 reference

Microwave Breast Imaging Techniques and Measurement Systems

Electromagnetic waves at microwave frequencies allow penetration into many optically non-transparent mediums such as biological tissues. Over the past 30 years, researchers have extensively investigated microwave imaging (MI) approaches including imaging algorithms, measurement systems and applications in biomedical fields, such as breast tumor detection, brain stroke detection, heart imaging and bone imaging. Successful clinical trials of MI for breast imaging brought worldwide excitation, and this achievement further confirmed that the MI has potential to become a low-risk and cost-effective alternative to existing medical imaging tools such as X-ray mammography for early breast cancer detection. This chapter offers comprehensive descriptions of the most important MI approaches for early breast cancer detection, including reconstruction procedures and measurement systems as well as apparatus

The Future of High Frequency Circuit Design

The cut-off wavelengths of integrated silicon transistors have exceeded the die sizes of the chips being fabricated with them. Combined with the ability to integrate billions of transistors on the same die, this size-wavelength cross-over has produced a unique opportunity for a completely new class of holistic circuit design combining electromagnetics, device physics, circuits, and communication system theory in one place. In this paper, we discuss some of these opportunities and their associated challenges in greater detail and provide a few of examples of how they can be used in practice