68,562 research outputs found

    Test item taxonomy based of functional criteria

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    There are many taxonomies that try to classify and apply some consistency to the very many item types currently in existence. They all have various limitations, however, such as ambiguous classification criteria, little discrimination between format types, and referring almost exclusively to pen-and-paper or screen-based items. This paper aims to overcome these limitations by proposing a new item format taxonomy based on functional criteria. Current classifications are reviewed, the criteria they are based on are examined and their limitations are identified. The proposed alternative classification identifies four essential components of items according to function: the structure of the included content, the device used for transmission of the question to the examinee, the device for receiving the response, and the instructions to the examinee about how to understand and respond to the item. The combination of different facets of these four components allows any format of item to be classified, both existing formats and those that may appear in the future. In addition to systematically and coherently classifying items, this new taxonomy may also be of great utility in the construction and research of new items. The proposed model is illustrated by examples showing how specific items are classified, using a checklist as a guide.Ministerio de Economía y Competitividad de España PSI2014-56114-PMinisterio de Economía y Competitividad de España PSI2017-85724-

    Two-particle irreducible effective action approach to nonlinear current conserving approximations in driven systems

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    Using closed-time path two-particle irreducible coarse-grained effective action (CTP 2PI CGEA) techniques, we study the response of an open interacting electronic system to time-dependent external electromagnetic fields. We show that the CTP 2PI CGEA is invariant under a simultaneous gauge transformation of the external field and the full Schwinger-Keldysh propagator, and that this property holds even when the loop expansion of the CTP 2PI CGEA is truncated at arbitrary order. The effective action approach provides a systematic way of calculating the propagator and response functions of the system, via the Schwinger-Dyson equation and the Bethe-Salpeter equations, respectively. We show that, due to the invariance of the CTP 2PI CGEA under external gauge transformations, the response functions calculated from it satisfy the Ward-Takahashi hierarchy, thus warranting the conservation of the electronic current beyond the expectation value level. We also clarify the connection between nonlinear response theory and the WT hierarchy, and discuss an example of an ad hoc approximation that violate it. These findings may be useful in the study of current fluctuations in correlated electronic pumping devices.Comment: 30 pages. Accepted for publication in JPC

    3D bioprinted human cortical neural constructs derived from induced pluripotent stem cells

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    Bioprinting techniques use bioinks made of biocompatible non-living materials and cells to build 3D constructs in a controlled manner and with micrometric resolution. 3D bioprinted structures representative of several human tissues have been recently produced using cells derived by differentiation of induced pluripotent stem cells (iPSCs). Human iPSCs can be differentiated in a wide range of neurons and glia, providing an ideal tool for modeling the human nervous system. Here we report a neural construct generated by 3D bioprinting of cortical neurons and glial precursors derived from human iPSCs. We show that the extrusion-based printing process does not impair cell viability in the short and long term. Bioprinted cells can be further differentiated within the construct and properly express neuronal and astrocytic markers. Functional analysis of 3D bioprinted cells highlights an early stage of maturation and the establishment of early network activity behaviors. This work lays the basis for generating more complex and faithful 3D models of the human nervous systems by bioprinting neural cells derived from iPSCs

    A molecular approach to complex adaptive systems

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    Complex Adaptive Systems (CAS) are dynamical networks of interacting agents which as a whole determine the behavior, adaptivity and cognitive ability of the system. CAS are ubiquitous and occur in a variety of natural and artificial systems (e.g., cells, societies, stock markets). To study CAS, Holland proposed to employ an agent-based system in which Learning Classifier Systems (LCS) were used to determine the agents behavior and adaptivity. We argue that LCS are limited for the study of CAS: the rule-discovery mechanism is pre-specified and may limit the evolvability of CAS. Secondly, LCS distinguish a demarcation between messages and rules, however operations are reflexive in CAS, e.g., in a cell, an agent (a molecule) may both act as a message (substrate) and as a catalyst (rule). To address these issues, we proposed the Molecular Classifier Systems (MCS.b), a string-based Artificial Chemistry based on Holland’s broadcast language. In the MCS.b, no explicit fitness function or rule discovery mechanism is specified, moreover no distinction is made between messages and rules. In the context of the ESIGNET project, we employ the MCS.b to study a subclass of CAS: Cell Signaling Networks (CSNs) which are complex biochemical networks responsible for coordinating cellular activities. As CSNs occur in cells, these networks must replicate themselves prior to cell division. In this paper we present a series of experiments focusing on the self-replication ability of these CAS. Results indicate counter intuitive outcomes as opposed to those inferred from the literature. This work highlights the current deficit of a theoretical framework for the study of Artificial Chemistries

    Multimedia information technology and the annotation of video

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    The state of the art in multimedia information technology has not progressed to the point where a single solution is available to meet all reasonable needs of documentalists and users of video archives. In general, we do not have an optimistic view of the usability of new technology in this domain, but digitization and digital power can be expected to cause a small revolution in the area of video archiving. The volume of data leads to two views of the future: on the pessimistic side, overload of data will cause lack of annotation capacity, and on the optimistic side, there will be enough data from which to learn selected concepts that can be deployed to support automatic annotation. At the threshold of this interesting era, we make an attempt to describe the state of the art in technology. We sample the progress in text, sound, and image processing, as well as in machine learning

    Computational Visualistics: Dealing with Pictures in Computer Science

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    Building blocks from many disciplines have to be integrated into a general science of images. Computational visualistics has been formed as a contributing field embracing all aspects of dealing with images computationally. Two basic concepts of computer science are introduced. Applied to the concept "image", they determine the methodological core of computational visualistics. As the contribution of computer science to the subject of image theory, interactive pictures are examined. Finally, relations to other "image sciences" are sketched. * * * Bausteine vieler Disziplinen müssen in eine allgemeine Bildwissenschaft integriert werden. Als Beitrag aus der Informatik versteht sich die Computervisualistik, die alle Aspekte rechnergestützten Umgangs mit Bildern umfaßt. Zwei Grundbegriffe der Informatik werden vorgestellt und bestimmen, auf den Begriff "Bild" angewendet, den methodologischen Kern der Computervisualistik. Als Beitrag der Informatik zum Gegenstand der Bildtheorie werden interaktive Bilder betrachtet. Schließlich werden die Beziehungen zu anderen "Bildwissenschaften" kurz umrissen
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