4,845 research outputs found
On scratching your own itch
Following Massimo Banzi's comment that the Arduino development board might be seen as a means of ‘scratching your own itch’, this paper explores the concept of affect in relation to physical computing, and investigates the ways in which cybernetic and networked objects could be said to enact a series of process-philosophical and object-oriented tensions. In so doing it addresses the cultural saturation of Arduino and its employment in an array of institutional, artistic and activist contexts, and brings this to bear on the conflict between the process philosophy of Gilles Deleuze and the more directly object-oriented perspectives of Graham Harman, Ian Bogost and Bruno Latour. Framing the enquiry around the at once ethico-aesthetic and speculative realist questions of what it is to ‘scratch' and what it is to ‘itch', the paper examines micro- and macro-political agency in the context of physical computing—contrasting process philosophy's pronounced notion of affective, connective, creative differentiation with the black-boxed, withdrawn objects of object-oriented philosophy, and its quasi-causal mode of aesthetic interaction
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Exploring content and psychometric validity of newly developed assessment tools for itch and skin pain in atopic dermatitis.
BackgroundAtopic dermatitis (AD) is a common skin disorder characterized by chronic inflammation, altered skin barrier function, and inflammatory cell skin infiltration that decreases health-related quality of life (HRQoL). The study objective was to understand the patient perspective of AD burden and determine suitable patient-reported outcome (PRO) measures.MethodsThis mixed methods study involved the collection of qualitative and quantitative information from adults (≥ 18 years old) and adolescents (12 - 17 years old) with clinician-confirmed AD regarding their experiences of AD symptoms and its impact on HRQoL. The first part of the study included three stages: in-person concept elicitation (CE) interviews, a 2-week daily electronic diary (eDiary) study, and in-person cognitive debriefing (CD) interviews. An Itch numeric rating scale (NRS) (v1.0) and a Skin Pain NRS (v1.0) evaluation during CD interviews required participants to think about their 'worst' itch and 'worst' skin pain in the past 24 h. Other PRO measures allowed for psychometric testing. The second part of the study involved telephone-depth interviews (TDIs) and qualitative feedback from participants who had not participated in the CD interviews. Qualitative data were thematically analyzed. Psychometric evaluation of NRS measures was performed using eDiary data.ResultsIn the CE interviews, itch and/or itching and skin pain were the most prevalent symptoms consistently discussed by participants. Both NRS measures demonstrated strong psychometric reliability and were applicable across ages with suitable concurrent validity. During the CD interviews, some participants focused their answers on their 'average' itch/itching in the past 24 h, rather than their 'worst' itch. Some participants answered the Skin Pain NRS thinking about general pain or other types of pain, rather than skin pain specifically. Consequently, modifications to both measures addressed these issues and re-tested as paper-and-pen versions in subsequent TDIs. Itch NRS (v2.0) modifications helped participants focus on their worst itching. Most participants preferred Skin Pain NRS v2.0b, which included skin pain descriptors.ConclusionsItching and skin pain are the most important and relevant AD symptoms. The Itch NRS (v2.0) and Skin Pain NRS (v2.0b) appear to be appropriate endpoints for the assessment of itching and skin pain severity for clinical trials with adults and adolescents with AD
Outlook Magazine, Winter 2014
https://digitalcommons.wustl.edu/outlook/1194/thumbnail.jp
Environmental influences on induction of itching and scratching using immersive virtual reality
Chronic itching is a serious and uncomfortable condition. The scratch response might result in a vicious cycle of alternating itching and scratching. To develop psychological interventions for people suffering from chronic itching and to break the vicious itch-scratching-itch cycle, it is important to elucidate which environmental factors trigger itch sensations. Virtual reality (VR) techniques provide a useful tool to examine specific content characteristics in a three-dimensional (3D VR) environment and their influences on itch sensations and scratching behaviour. This article describes two experiments in which we focused on the effects of environmental information on itching and scratching behaviour. Additionally, in the second experiment, we examined the influence of having a chronic skin condition on sensitivity to itch induction. We found evidence for the importance of the content of audio–visual materials for the effectiveness in inducing feelings of itch in the observers. In both experiments, we observed significantly higher levels of perceived itch in the itch-inducing conditions than in the control condition. Moreover, the results showed that elevated levels of perceived itch were associated with an increase in scratching behaviours, which was especially salient in the contagious itch condition, in which perceived itch was accompanied by a significant increase in the number of scratches. Experiment 2 additionally showed increased perceived itch levels in participants who reported having a chronic skin condition, reflecting higher sensitivity to itch-inducing audio–visual stimuli in this group than in participants without a chronic skin condition. Based on the results we concluded that directing attention towards itch- or scratch aspects of related information in the environment and to the consequences for one’s own skin are effective tools to induce itch sensations and scratching behaviour. This knowledge provides tools for developing novel strategies in advising and treating people suffering from chronic itching and breaking the vicious itch-scratching-itch cycle
Usability and open source software.
Open source communities have successfully developed many pieces of software although most computer users only use proprietary applications. The usability of open source software is often regarded as one reason for this limited distribution. In this paper we review the existing evidence of the usability of open source software and discuss how the characteristics of open-source development influence usability. We describe how existing human-computer interaction techniques can be used to leverage distributed networked communities, of developers and users, to address issues of usability
Atopic dermatitis and distress
Atopic dermatitis (AD) is a chronic, inflammatory skin condition characterized by itching,
redness, and skin lesions, affecting approximately 10–20% of children and 1–3% of adults
worldwide. Distress associated with AD can negatively impact quality of life, work, and
daily activities.
The research aims were to explore the role of stress in AD patients and to further
investigate brain activity during stress in AD patients compared with controls. Further, one
possible mediator related to skin inflammation and stress, calcitonin gene-related peptide
(CGRP), was studied in skin from AD patients and controls, and related to psychodemographic measurements.
The initial parts of the project involved focus groups with patients and an online survey.
Results from the focus group study and the survey study underlined the importance of stress
as a trigger and worsening factor for patients with AD. Both studies indicated that stress,
especially chronic stress, could be an important worsening factor. Decision-making and
unforeseen events were often mentioned as stress triggers. In both the focus groups and the
survey study, patients rated stress as of greater importance than climate factors. Itch was
reported to be a result of stress and the type of stress possibly affected the nature of the
pruritus experienced by patients. Furthermore, physical exercise was reported to have
beneficial effects, something that was found in both the focus groups and the survey.
Differences were found in possible mechanisms for stress processing in AD patients
compared with controls. Reduced deactivation in the default mode network in response to
stress (an arithmetic test) indicated that there is likely a cognitive functional variability in
AD patients compared with healthy control subjects, manifested as lowered inhibition
ability under psychological stress. This was also supported by different correlations
between brain activities and various psycho-demographic data. Findings from a functional
magnetic resonance imaging study indicated that psychological stress affected brain
activities in the motor cortex, the somatosensory association cortex, and perception and
sensory integration processing among AD patients.
An immunohistochemical study showed an increase of CGRP in nerve-like fibers and
inflammatory cells in inflamed skin of AD patients compared with non-lesional skin. The
increase of CGRP-positive nerve-like fibers in skin correlated with depressive and anxiety
scores in the patients.
The results showed that psychological stress was an important trigger factor for AD and both
differences in central processing of stress in AD and peripheral changes in CGRP levels in
skin were observed. This emphasizes the importance of a holistic approach to treatment of
AD, with the possibility for healthcare to offer more individualized treatment depending on
each patient’s challenges and needs
An Exploration of Life With a Chronic Skin Condition
Despite considerable prevalence and clinical impact, chronic skin conditions have received little sociological attention. This research examines the social implications of living with a chronic skin condition, based on the thematic analysis of in-depth interviews featuring 24 adults with experiences of eczema, psoriasis or acne. Drawing on Bourdieusian field theory and corporeal phenomenology, this thesis brings new insight to the disembodying experiences of disordered skin, strategies enacted for their management, and the wider implications of disordered skin on social participation. Illustrating experiences of social dys-appearance, individuals are found to negotiate stigma, both enacted and perceived, based on normative expectations of bodily presentation. Employing the notion of aesthetic capital, disordered skin is shown to impair possibilities for aesthetic distinction and undermine a sense of capability in personal and working roles. Faced with disabling spatialities and difficulties surrounding disclosure, individuals develop anticipatory dispositions and a range of time-space tactics. The corporeal dys-appearance of disordered skin demands that individuals respond through laborious practices which often take on Sisyphean attributes. A novel concept of “containing” is introduced as a type of skin work reflecting how managing disordered skin requires attention to clearing up exudations of “dirty” bodily substances, such as skin flakes, blood, pus, and the remnants of topical treatments, to avoid soiling external environments. Pharmaceutical treatments are found to be a source of deep ambivalence. Moreover, individuals value agency in their treatment protocols and, where capital resources allow, enact resistance to medical authority through experimentation with alternative strategies and practices of self-medication. This study highlights a need to accommodate the additional labour demands of life with chronic skin conditions, and the desire for agency in treatment, through policy and practice measures. Further efforts are needed to address the impact of inequalities of access to resources on the burden of managing chronic illness
Main problems experienced by children with epidermolysis bullosa:A qualitative study with semi-structured interviews
The objective of this study was to identify and specify the problems of children with epidermolysis bullosa. The questions explored were: (i) What do children with epidermolysis bullosa experience as the most difficult problems; (it) What is the impact of these problems on their daily life; and (iii) Do these experiences differ between mildly and severely affected children? Qualitative research methodology was used, comprising a series of semi-structured interviews with children with different (sub)types of epidermolysis bullosa. The interviews were analysed systematically with help of the qualitative software package Atlas-ti. Five main themes were found: (i) having an itchy skin, (ii) being in pain, (iii) having difficulties with participation, (iv) lack of understanding of others, and (v) the feeling of being different. Severely affected children suffered most from itch and treatment-related pain. Mildly affected children had more problems with activity-related pain. Mildly affected children also had more concerns about their appearance and the teasing and staring of others than did severely affected children. Both groups had difficulties with participation, the visibility of their disease and the feeling of being different
A comparative approach to social learning from the bottom up
The aim of this thesis is to examine the cognitive processes of social learning from the bottom up. In the field of comparative psychology, an overemphasis on understanding complex cognitive processes in nonhuman animals (e.g. empathy, imitation), may be detrimental to the study of simpler mechanisms. In this thesis, I report five studies of simple cognitive processes related to social learning. A series of experiments with human children and capuchin monkeys (Sapajus sp.), examined action imitation and identified a possible role for associative learning in the development of this ability. An analysis of observational data from captive capuchins explored a number of lesser-studied social learning phenomena, including behavioural synchrony, the neighbour effect, and group-size effects. The results of this study emphasise the importance of exploring behaviour at a number of levels to appreciate the dynamic nature of social influence. Two final experiments examined social contagion in capuchin monkeys, and highlight the importance of describing the relationship between behaviour and emotion to properly understand more complex social cognition. Together, these studies demonstrate how approaching human and nonhuman behaviour from the bottom up, as well as from the top down, can contribute to a better comparative science of social learning
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