Ultrasound Signal Processing: From Models to Deep Learning

Medical ultrasound imaging relies heavily on high-quality signal processing algorithms to provide reliable and interpretable image reconstructions. Hand-crafted reconstruction methods, often based on approximations of the underlying measurement model, are useful in practice, but notoriously fall behind in terms of image quality. More sophisticated solutions, based on statistical modelling, careful parameter tuning, or through increased model complexity, can be sensitive to different environments. Recently, deep learning based methods have gained popularity, which are optimized in a data-driven fashion. These model-agnostic methods often rely on generic model structures, and require vast training data to converge to a robust solution. A relatively new paradigm combines the power of the two: leveraging data-driven deep learning, as well as exploiting domain knowledge. These model-based solutions yield high robustness, and require less trainable parameters and training data than conventional neural networks. In this work we provide an overview of these methods from the recent literature, and discuss a wide variety of ultrasound applications. We aim to inspire the reader to further research in this area, and to address the opportunities within the field of ultrasound signal processing. We conclude with a future perspective on these model-based deep learning techniques for medical ultrasound applications

Advanced Restoration Techniques for Images and Disparity Maps

With increasing popularity of digital cameras, the field of Computa- tional Photography emerges as one of the most demanding areas of research. In this thesis we study and develop novel priors and op- timization techniques to solve inverse problems, including disparity estimation and image restoration. The disparity map estimation method proposed in this thesis incor- porates multiple frames of a stereo video sequence to ensure temporal coherency. To enforce smoothness, we use spatio-temporal connec- tions between the pixels of the disparity map to constrain our solution. Apart from smoothness, we enforce a consistency constraint for the disparity assignments by using connections between the left and right views. These constraints are then formulated in a graphical model, which we solve using mean-field approximation. We use a filter-based mean-field optimization that perform efficiently by updating the dis- parity variables in parallel. The parallel updates scheme, however, is not guaranteed to converge to a stationary point. To compare and demonstrate the effectiveness of our approach, we developed a new optimization technique that uses sequential updates, which runs ef- ficiently and guarantees convergence. Our empirical results indicate that with proper initialization, we can employ the parallel update scheme and efficiently optimize our disparity maps without loss of quality. Our method ranks amongst the state of the art in common benchmarks, and significantly reduces the temporal flickering artifacts in the disparity maps. In the second part of this thesis, we address several image restora- tion problems such as image deblurring, demosaicing and super- resolution. We propose to use denoising autoencoders to learn an approximation of the true natural image distribution. We parametrize our denoisers using deep neural networks and show that they learn the gradient of the smoothed density of natural images. Based on this analysis, we propose a restoration technique that moves the so- lution towards the local extrema of this distribution by minimizing the difference between the input and output of our denoiser. Weii demonstrate the effectiveness of our approach using a single trained neural network in several restoration tasks such as deblurring and super-resolution. In a more general framework, we define a new Bayes formulation for the restoration problem, which leads to a more efficient and robust estimator. The proposed framework achieves state of the art performance in various restoration tasks such as deblurring and demosaicing, and also for more challenging tasks such as noise- and kernel-blind image deblurring. Keywords. disparity map estimation, stereo matching, mean-field optimization, graphical models, image processing, linear inverse prob- lems, image restoration, image deblurring, image denoising, single image super-resolution, image demosaicing, deep neural networks, denoising autoencoder

An Adaptive and Robust Deep Learning Framework for THz Ultra-Massive MIMO Channel Estimation

Terahertz ultra-massive MIMO (THz UM-MIMO) is envisioned as one of the key enablers of 6G wireless networks, for which channel estimation is highly challenging. Traditional analytical estimation methods are no longer effective, as the enlarged array aperture and the small wavelength result in a mixture of far-field and near-field paths, constituting a hybrid-field channel. Deep learning (DL)-based methods, despite the competitive performance, generally lack theoretical guarantees and scale poorly with the size of the array. In this paper, we propose a general DL framework for THz UM-MIMO channel estimation, which leverages existing iterative channel estimators and is with provable guarantees. Each iteration is implemented by a fixed point network (FPN), consisting of a closed-form linear estimator and a DL-based non-linear estimator. The proposed method perfectly matches the THz UM-MIMO channel estimation due to several unique advantages. First, the complexity is low and adaptive. It enjoys provable linear convergence with a low per-iteration cost and monotonically increasing accuracy, which enables an adaptive accuracy-complexity tradeoff. Second, it is robust to practical distribution shifts and can directly generalize to a variety of heavily out-of-distribution scenarios with almost no performance loss, which is suitable for the complicated THz channel conditions. For practical usage, the proposed framework is further extended to wideband THz UM-MIMO systems with beam squint effect. Theoretical analysis and extensive simulation results are provided to illustrate the advantages over the state-of-the-art methods in estimation accuracy, convergence rate, complexity, and robustness.Comment: 15 pages, 11 figures, 5 tables, accepted by IEEE Journal of Selected Topics in Signal Processing (JSTSP