115 research outputs found
Efficient Two-Stage Group Testing Algorithms for Genetic Screening
Efficient two-stage group testing algorithms that are particularly suited for
rapid and less-expensive DNA library screening and other large scale biological
group testing efforts are investigated in this paper. The main focus is on
novel combinatorial constructions in order to minimize the number of individual
tests at the second stage of a two-stage disjunctive testing procedure.
Building on recent work by Levenshtein (2003) and Tonchev (2008), several new
infinite classes of such combinatorial designs are presented.Comment: 14 pages; to appear in "Algorithmica". Part of this work has been
presented at the ICALP 2011 Group Testing Workshop; arXiv:1106.368
Group Divisible Codes and Their Application in the Construction of Optimal Constant-Composition Codes of Weight Three
The concept of group divisible codes, a generalization of group divisible
designs with constant block size, is introduced in this paper. This new class
of codes is shown to be useful in recursive constructions for constant-weight
and constant-composition codes. Large classes of group divisible codes are
constructed which enabled the determination of the sizes of optimal
constant-composition codes of weight three (and specified distance), leaving
only four cases undetermined. Previously, the sizes of constant-composition
codes of weight three were known only for those of sufficiently large length.Comment: 13 pages, 1 figure, 4 table
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