On cycling in the simplex method of the Transportation Problem

This paper shows that cycling of the simplex method for the m×n Transportation Problem where k-1 zero basic variables are leaving and reentering the basis does not occur once it does not occur in the k×k Assignment Problem. A method to disprove cycling for a particular k is applied for k=2,3,34,5 and 6.Transportation Problem, Assignment Problem, cycling, basic solution, node, link, directed weighted tree.

Switching in heteroclinic networks

We study the dynamics near heteroclinic networks for which all eigenvalues of the linearization at the equilibria are real. A common connection and an assumption on the geometry of its incoming and outgoing directions exclude even the weakest forms of switching (i.e. along this connection). The form of the global transition maps, and thus the type of the heteroclinic cycle, plays a crucial role in this. We look at two examples in $\mathbb{R}^5$, the House and Bowtie networks, to illustrate complex dynamics that may occur when either of these conditions is broken. For the House network, there is switching along the common connection, while for the Bowtie network we find switching along a cycle

Algorithms for network piecewise-linear programs

In this paper a subarea of Piecewise-Linear Programming named network Piecewise-Linear Programming (NPLP) is discussed. Initially the problem formulation, main efinitins and related Concepts are presented. In the sequence of the paper, four specialized algorithms for NPLP, as well as the results of a preliminary computational study, are presented

The Ca2+ transient as a feedback sensor controlling cardiomyocyte ionic conductances in mouse populations.

Conductances of ion channels and transporters controlling cardiac excitation may vary in a population of subjects with different cardiac gene expression patterns. However, the amount of variability and its origin are not quantitatively known. We propose a new conceptual approach to predict this variability that consists of finding combinations of conductances generating a normal intracellular Ca2+ transient without any constraint on the action potential. Furthermore, we validate experimentally its predictions using the Hybrid Mouse Diversity Panel, a model system of genetically diverse mouse strains that allows us to quantify inter-subject versus intra-subject variability. The method predicts that conductances of inward Ca2+ and outward K+ currents compensate each other to generate a normal Ca2+ transient in good quantitative agreement with current measurements in ventricular myocytes from hearts of different isogenic strains. Our results suggest that a feedback mechanism sensing the aggregate Ca2+ transient of the heart suffices to regulate ionic conductances

Survival of dominated strategies under evolutionary dynamics

We show that any evolutionary dynamic that satisfies three mild requirements— continuity, positive correlation, and innovation—does not eliminate strictly dominated strategies in all games. Likewise, we demonstrate that existing elimination results for evolutionary dynamics are not robust to small changes in the specifications of the dynamics