880 research outputs found

    QKD based on symmetric entangled Bernstein-Vazirani

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    This paper introduces a novel entanglement-based QKD protocol, that makes use of a modified symmetric version of the Bernstein-Vazirani algorithm, in order to achieve a secure and efficient key distribution. Two variants of the protocol, one fully symmetric and one semi-symmetric, are presented. In both cases, the spatially separated Alice and Bob share multiple EPR pairs, one qubit of the pair each. The fully symmetric version allows both parties to input a secret key from the irrespective location and, finally, acquire in the end a totally new and original key, an idea which was inspired by the Diffie-Hellman key exchange protocol. In the semi-symmetric version, Alice sends her chosen secret key to Bob (or vice versa). Furthermore, their performance against an eavesdropper's attack is analyzed. Finally, in order to illustrate the operation of the protocols in practice, two small scale but detailed examples are given.Comment: 16 pages, 8 figure

    The Disposal Mode of Maine’s Waste Governance

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    Maine’s materials management system is stuck in a disposal mode of waste governance. Despite significant investments in programs and policies designed to reduce the amount of waste the state buries each year, recent shocks and uncertainties have resulted in increased waste generation and disposal. This paper analyzes specific ways through which materials management in Maine has become locked in to a disposal mode of waste governance. We build a framework to help understand various forms of lock-in and how they might be unlocked. This framework is applied to the extended producer responsibility packaging law that is presently under the rule-making process in Maine, the first state to adopt such a policy in the United States

    E-health and e-welfare of Finland - Check point 2015

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    The new e-health and e-welfare strategy in Finland aims to support the renewal of the social welfare and health care services and the active role of citizens in maintaining their own well-being. The means include the development of knowledge management and increasing the provision of online services. The overall structural changes taking place in Finnish health and social care will also influence information and communication technologies (ICT). The report provides information about the change in the services and the service system brought on by ICT over time. The report illustrates the status in 2014 as compared with the strategic outcomes and objectives set on ICT to support performance and renewal of social welfare and health care. The results are condensed from four surveys for a comprehensive view: availability and use of ICT in health care as well as in social care, usability of the systems for physicians, and citizens´ use and anticipations. These are accompanied by a review of Finnish health care system and ICT development. For the international reader, the report provides an overview of progressive nationwide activities towards better e-services in Finland

    Automated tools and techniques for distributed Grid Software: Development of the testbed infrastructure

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    Grid technology is becoming more and more important as the new paradigm for sharing computational resources across different organizations in a secure way. The great powerfulness of this solution, requires the definition of a generic stack of services and protocols and this is the scope of the different Grid initiatives. As a result of international collaborations for its development, the Open Grid Forum created the Open Grid Services Architecture (OGSA) which aims to define the common set of services that will enable interoperability across the different implementations. This master thesis has been developed in this framework, as part of the two European-funded projects ETICS and OMII-Europe. The main objective is to contribute to the design and maintenance of large distributed development projects with the automated tool that enables to implement Software Engineering techniques oriented to achieve an acceptable level of quality at the release process. Specifically, this thesis develops the testbed concept as the virtual production-like scenario where to perform compliance tests. As proof of concept, the OGSA Basic Execution Service has been chosen in order to implement and execute conformance tests within the ETICS automated testbed framework

    From Artefacts to Infrastructures

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    In their initial articulation of the direction of the CSCW field, scholars advanced an open-ended agenda. This continuing commitment to open-ness to different contexts and approaches is not, however, reflected in the contents of the major CSCW outlets. The field appears to privilege particular forms of cooperative work. We find many examples of what could be described as ‘localist studies’, restricted to particular settings and timeframes. This focus on the ‘here and now’ is particularly problematic when one considers the kinds of large-scale, integrated and interconnected workplace information technologies—or what we are calling Information Infrastructures—increasingly found within and across organisations today. CSCW appears unable (or unwilling) to grapple with these technologies—which were at the outset envisaged as falling within the scope of the field. Our paper hopes to facilitate greater CSCW attention to Information Infrastructures through offering a re-conceptualisation of the role and nature of ‘design’. Design within an Information Infrastructures perspective needs to accommodate non-local constraints. We discuss two such forms of constraint: standardisation (how local fitting entails unfitting at other sites) and embeddedness (the entanglement of one technology with other apparently unrelated ones). We illustrate these themes through introducing case material drawn on from a number of previous studies

    The Synthesis and Characterization of Multifunctional Nanoparticles of Elastin-Like Polypeptides for Theranostic Applications

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    Theranostics is a promising field that aims to combine therapeutics and diagnostics into single multifunctional formulations. This field is driven by advancements in nanotechnology and specifically in the creation of multifunctional nanoparticles capable of providing the necessary functionalities. Elastin-like polypeptides (ELPs) are a class of environmentally responsive biopolymers that are known to undergo a transition in response to various stimuli. The organic nature of ELPs along with the ability to control their design at the gene level and the aforementioned responsive behavior make them a promising candidate for use in theranostic systems. The system presented here is one of the first examples of using ELPs as the base for multifunctional theranostic nanoparticles. Presented in this study is a fully protein based self-assembling nanoparticle system based on micelles of ELPs for use in theranostic applications. Micelle forming ELP constructs have been modified through the fusion of the protein based MRI contrast agent CA1.CD2 to the C terminal of existing protein constructs. Micelles were then crosslinked into stable nanoparticles that relied only on changes in temperature to drive the transition. In addition to that, a targeting peptide has been added to the system as well to provide active targeting to cancer cells. As a contrast agent the system has been shown to bind and retain gadolinium while effectively providing contrast in T1 weighted imaging and having higher relaxivity values than clinical contrast agents. Modification of the architecture of the construct through changes of the tail length, and through creation of mixtures did not drastically affect the behavior of the system demonstrating its flexibility. Here I detail, the design, synthesis of the expression, purification and characterization of all the required properties of the constructs

    The Synthesis and Characterization of Multifunctional Nanoparticles of Elastin-Like Polypeptides for Theranostic Applications

    Get PDF
    Theranostics is a promising field that aims to combine therapeutics and diagnostics into single multifunctional formulations. This field is driven by advancements in nanotechnology and specifically in the creation of multifunctional nanoparticles capable of providing the necessary functionalities. Elastin-like polypeptides (ELPs) are a class of environmentally responsive biopolymers that are known to undergo a transition in response to various stimuli. The organic nature of ELPs along with the ability to control their design at the gene level and the aforementioned responsive behavior make them a promising candidate for use in theranostic systems. The system presented here is one of the first examples of using ELPs as the base for multifunctional theranostic nanoparticles. Presented in this study is a fully protein based self-assembling nanoparticle system based on micelles of ELPs for use in theranostic applications. Micelle forming ELP constructs have been modified through the fusion of the protein based MRI contrast agent CA1.CD2 to the C terminal of existing protein constructs. Micelles were then crosslinked into stable nanoparticles that relied only on changes in temperature to drive the transition. In addition to that, a targeting peptide has been added to the system as well to provide active targeting to cancer cells. As a contrast agent the system has been shown to bind and retain gadolinium while effectively providing contrast in T1 weighted imaging and having higher relaxivity values than clinical contrast agents. Modification of the architecture of the construct through changes of the tail length, and through creation of mixtures did not drastically affect the behavior of the system demonstrating its flexibility. Here I detail, the design, synthesis of the expression, purification and characterization of all the required properties of the constructs

    E-health and e-welfare of Finland : Check Point 2022

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    The report provides an overview of progressive nationwide activities towards better e-services in Finland. The information system services of social welfare and health care are monitored by systematic gathering, analysis, and use of data, which allows the tracking of the progress of operations and the realisation of goals. In 2020 and 2021, six data collections were carried out to produce data for the monitoring of the Finnish ‘Information to support well-being and service renewal, eHealth and eSocial Strategy’. Some of the results presented in the report are also openly available in database cubes

    PPEPR: plug and play electronic patient records.

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    ABSTRACT The integration of Electronic Patient Record (EPR) systems is at the centre of many of the new regional and national initiatives to integrate clinical processes across department, region, and national levels. Web Service technologies offer significant solutions to provide an interoperable communication infrastructure but are unable to support precise definitions for healthcare messages, functionality, and standards, required for making meaningful integration. The lack of interoperability within healthcare standards adds complexity to the initiatives. This heterogeneity exists within two versions of same standard (e.g. HL7), and also between standards (e.g. HL7, openEHR, CEN TC/251 13606). We therefore introduce an integration platform PPEPR (Plug and Play Electronic Patient Records), which is based on the principles of a semantic Service-Oriented Architecture (sSOA). PPEPR solves the problem of interoperability at the semantic level. A key focus of PPEPR is that once a patient information is captured, should be available for use across all potential care processes

    Secure and seamless prepayment for wireless mesh networks

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    Wireless Mesh Network (WMN) is multi-hop high-speed networking technology for broadband access. Compared to conventional network service providing systems, WMNs are easy to deploy and cost-effective. In this thesis, we propose a secure and seamless prepayment system for the Internet access through WMNs (SSPayWMN). Practical payment systems for network access generally depend on trustworthiness of service provider. However, in real life, service providers may unintentionally overcharge their clients. This misbehavior in the system may cause disputes between the clients and the service providers. Even if the service provider is rightful, it is very difficult to convince the customer since the service providers generally do not have justifiable proofs that can easily be denied by the clients. The main goal of SSPayWMN is to provide a secure payment scheme, which is fair to both operators and clients. Using cryptographic tools and techniques, all system entities are able to authenticate each other and provide/get service in an undeniable way. Moreover, SSPayWMN provides privacy and untraceability in order not to track down particular user’s network activities. We implemented SSPayWMN on a network simulator (ns-3) and performed performance evaluation to understand the latency caused by the system's protocols. Our results show that our protocols achieve low steady state latency and in overall put very little burden on the system
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