Dirichlet Bayesian Network Scores and the Maximum Relative Entropy Principle

A classic approach for learning Bayesian networks from data is to identify a maximum a posteriori (MAP) network structure. In the case of discrete Bayesian networks, MAP networks are selected by maximising one of several possible Bayesian Dirichlet (BD) scores; the most famous is the Bayesian Dirichlet equivalent uniform (BDeu) score from Heckerman et al (1995). The key properties of BDeu arise from its uniform prior over the parameters of each local distribution in the network, which makes structure learning computationally efficient; it does not require the elicitation of prior knowledge from experts; and it satisfies score equivalence. In this paper we will review the derivation and the properties of BD scores, and of BDeu in particular, and we will link them to the corresponding entropy estimates to study them from an information theoretic perspective. To this end, we will work in the context of the foundational work of Giffin and Caticha (2007), who showed that Bayesian inference can be framed as a particular case of the maximum relative entropy principle. We will use this connection to show that BDeu should not be used for structure learning from sparse data, since it violates the maximum relative entropy principle; and that it is also problematic from a more classic Bayesian model selection perspective, because it produces Bayes factors that are sensitive to the value of its only hyperparameter. Using a large simulation study, we found in our previous work (Scutari, 2016) that the Bayesian Dirichlet sparse (BDs) score seems to provide better accuracy in structure learning; in this paper we further show that BDs does not suffer from the issues above, and we recommend to use it for sparse data instead of BDeu. Finally, will show that these issues are in fact different aspects of the same problem and a consequence of the distributional assumptions of the prior.Comment: 20 pages, 4 figures; extended version submitted to Behaviormetrik

An Empirical-Bayes Score for Discrete Bayesian Networks

Bayesian network structure learning is often performed in a Bayesian setting, by evaluating candidate structures using their posterior probabilities for a given data set. Score-based algorithms then use those posterior probabilities as an objective function and return the maximum a posteriori network as the learned model. For discrete Bayesian networks, the canonical choice for a posterior score is the Bayesian Dirichlet equivalent uniform (BDeu) marginal likelihood with a uniform (U) graph prior (Heckerman et al., 1995). Its favourable theoretical properties descend from assuming a uniform prior both on the space of the network structures and on the space of the parameters of the network. In this paper, we revisit the limitations of these assumptions; and we introduce an alternative set of assumptions and the resulting score: the Bayesian Dirichlet sparse (BDs) empirical Bayes marginal likelihood with a marginal uniform (MU) graph prior. We evaluate its performance in an extensive simulation study, showing that MU+BDs is more accurate than U+BDeu both in learning the structure of the network and in predicting new observations, while not being computationally more complex to estimate.Comment: 12 pages, PGM 201

Exploiting network topology for large-scale inference of nonlinear reaction models

The development of chemical reaction models aids understanding and prediction in areas ranging from biology to electrochemistry and combustion. A systematic approach to building reaction network models uses observational data not only to estimate unknown parameters, but also to learn model structure. Bayesian inference provides a natural approach to this data-driven construction of models. Yet traditional Bayesian model inference methodologies that numerically evaluate the evidence for each model are often infeasible for nonlinear reaction network inference, as the number of plausible models can be combinatorially large. Alternative approaches based on model-space sampling can enable large-scale network inference, but their realization presents many challenges. In this paper, we present new computational methods that make large-scale nonlinear network inference tractable. First, we exploit the topology of networks describing potential interactions among chemical species to design improved "between-model" proposals for reversible-jump Markov chain Monte Carlo. Second, we introduce a sensitivity-based determination of move types which, when combined with network-aware proposals, yields significant additional gains in sampling performance. These algorithms are demonstrated on inference problems drawn from systems biology, with nonlinear differential equation models of species interactions

Labeled Directed Acyclic Graphs: a generalization of context-specific independence in directed graphical models

We introduce a novel class of labeled directed acyclic graph (LDAG) models for finite sets of discrete variables. LDAGs generalize earlier proposals for allowing local structures in the conditional probability distribution of a node, such that unrestricted label sets determine which edges can be deleted from the underlying directed acyclic graph (DAG) for a given context. Several properties of these models are derived, including a generalization of the concept of Markov equivalence classes. Efficient Bayesian learning of LDAGs is enabled by introducing an LDAG-based factorization of the Dirichlet prior for the model parameters, such that the marginal likelihood can be calculated analytically. In addition, we develop a novel prior distribution for the model structures that can appropriately penalize a model for its labeling complexity. A non-reversible Markov chain Monte Carlo algorithm combined with a greedy hill climbing approach is used for illustrating the useful properties of LDAG models for both real and synthetic data sets.Comment: 26 pages, 17 figure

Bayesian Fused Lasso regression for dynamic binary networks

We propose a multinomial logistic regression model for link prediction in a time series of directed binary networks. To account for the dynamic nature of the data we employ a dynamic model for the model parameters that is strongly connected with the fused lasso penalty. In addition to promoting sparseness, this prior allows us to explore the presence of change points in the structure of the network. We introduce fast computational algorithms for estimation and prediction using both optimization and Bayesian approaches. The performance of the model is illustrated using simulated data and data from a financial trading network in the NYMEX natural gas futures market. Supplementary material containing the trading network data set and code to implement the algorithms is available online