71,268 research outputs found

    HTC Scientific Computing in a Distributed Cloud Environment

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    This paper describes the use of a distributed cloud computing system for high-throughput computing (HTC) scientific applications. The distributed cloud computing system is composed of a number of separate Infrastructure-as-a-Service (IaaS) clouds that are utilized in a unified infrastructure. The distributed cloud has been in production-quality operation for two years with approximately 500,000 completed jobs where a typical workload has 500 simultaneous embarrassingly-parallel jobs that run for approximately 12 hours. We review the design and implementation of the system which is based on pre-existing components and a number of custom components. We discuss the operation of the system, and describe our plans for the expansion to more sites and increased computing capacity

    MOLNs: A cloud platform for interactive, reproducible and scalable spatial stochastic computational experiments in systems biology using PyURDME

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    Computational experiments using spatial stochastic simulations have led to important new biological insights, but they require specialized tools, a complex software stack, as well as large and scalable compute and data analysis resources due to the large computational cost associated with Monte Carlo computational workflows. The complexity of setting up and managing a large-scale distributed computation environment to support productive and reproducible modeling can be prohibitive for practitioners in systems biology. This results in a barrier to the adoption of spatial stochastic simulation tools, effectively limiting the type of biological questions addressed by quantitative modeling. In this paper, we present PyURDME, a new, user-friendly spatial modeling and simulation package, and MOLNs, a cloud computing appliance for distributed simulation of stochastic reaction-diffusion models. MOLNs is based on IPython and provides an interactive programming platform for development of sharable and reproducible distributed parallel computational experiments

    Evaluator services for optimised service placement in distributed heterogeneous cloud infrastructures

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    Optimal placement of demanding real-time interactive applications in a distributed heterogeneous cloud very quickly results in a complex tradeoff between the application constraints and resource capabilities. This requires very detailed information of the various requirements and capabilities of the applications and available resources. In this paper, we present a mathematical model for the service optimization problem and study the concept of evaluator services as a flexible and efficient solution for this complex problem. An evaluator service is a service probe that is deployed in particular runtime environments to assess the feasibility and cost-effectiveness of deploying a specific application in such environment. We discuss how this concept can be incorporated in a general framework such as the FUSION architecture and discuss the key benefits and tradeoffs for doing evaluator-based optimal service placement in widely distributed heterogeneous cloud environments

    Learning and Management for Internet-of-Things: Accounting for Adaptivity and Scalability

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    Internet-of-Things (IoT) envisions an intelligent infrastructure of networked smart devices offering task-specific monitoring and control services. The unique features of IoT include extreme heterogeneity, massive number of devices, and unpredictable dynamics partially due to human interaction. These call for foundational innovations in network design and management. Ideally, it should allow efficient adaptation to changing environments, and low-cost implementation scalable to massive number of devices, subject to stringent latency constraints. To this end, the overarching goal of this paper is to outline a unified framework for online learning and management policies in IoT through joint advances in communication, networking, learning, and optimization. From the network architecture vantage point, the unified framework leverages a promising fog architecture that enables smart devices to have proximity access to cloud functionalities at the network edge, along the cloud-to-things continuum. From the algorithmic perspective, key innovations target online approaches adaptive to different degrees of nonstationarity in IoT dynamics, and their scalable model-free implementation under limited feedback that motivates blind or bandit approaches. The proposed framework aspires to offer a stepping stone that leads to systematic designs and analysis of task-specific learning and management schemes for IoT, along with a host of new research directions to build on.Comment: Submitted on June 15 to Proceeding of IEEE Special Issue on Adaptive and Scalable Communication Network
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