Feature-driven Volume Visualization of Medical Imaging Data

Direct volume rendering (DVR) is a volume visualization technique that has been proved to be a very powerful tool in many scientific visualization domains. Diagnostic medical imaging is one such domain in which DVR provides new capabilities for the analysis of complex cases and improves the efficiency of image interpretation workflows. However, the full potential of DVR in the medical domain has not yet been realized. A major obstacle for a better integration of DVR in the medical domain is the time-consuming process to optimize the rendering parameters that are needed to generate diagnostically relevant visualizations in which the important features that are hidden in image volumes are clearly displayed, such as shape and spatial localization of tumors, its relationship with adjacent structures, and temporal changes in the tumors. In current workflows, clinicians must manually specify the transfer function (TF), view-point (camera), clipping planes, and other visual parameters. Another obstacle for the adoption of DVR to the medical domain is the ever increasing volume of imaging data. The advancement of imaging acquisition techniques has led to a rapid expansion in the size of the data, in the forms of higher resolutions, temporal imaging acquisition to track treatment responses over time, and an increase in the number of imaging modalities that are used for a single procedure. The manual specification of the rendering parameters under these circumstances is very challenging. This thesis proposes a set of innovative methods that visualize important features in multi-dimensional and multi-modality medical images by automatically or semi-automatically optimizing the rendering parameters. Our methods enable visualizations necessary for the diagnostic procedure in which 2D slice of interest (SOI) can be augmented with 3D anatomical contextual information to provide accurate spatial localization of 2D features in the SOI; the rendering parameters are automatically computed to guarantee the visibility of 3D features; and changes in 3D features can be tracked in temporal data under the constraint of consistent contextual information. We also present a method for the efficient computation of visibility histograms (VHs) using adaptive binning, which allows our optimal DVR to be automated and visualized in real-time. We evaluated our methods by producing visualizations for a variety of clinically relevant scenarios and imaging data sets. We also examined the computational performance of our methods for these scenarios

Feature-driven Volume Visualization of Medical Imaging Data

Direct volume rendering (DVR) is a volume visualization technique that has been proved to be a very powerful tool in many scientific visualization domains. Diagnostic medical imaging is one such domain in which DVR provides new capabilities for the analysis of complex cases and improves the efficiency of image interpretation workflows. However, the full potential of DVR in the medical domain has not yet been realized. A major obstacle for a better integration of DVR in the medical domain is the time-consuming process to optimize the rendering parameters that are needed to generate diagnostically relevant visualizations in which the important features that are hidden in image volumes are clearly displayed, such as shape and spatial localization of tumors, its relationship with adjacent structures, and temporal changes in the tumors. In current workflows, clinicians must manually specify the transfer function (TF), view-point (camera), clipping planes, and other visual parameters. Another obstacle for the adoption of DVR to the medical domain is the ever increasing volume of imaging data. The advancement of imaging acquisition techniques has led to a rapid expansion in the size of the data, in the forms of higher resolutions, temporal imaging acquisition to track treatment responses over time, and an increase in the number of imaging modalities that are used for a single procedure. The manual specification of the rendering parameters under these circumstances is very challenging. This thesis proposes a set of innovative methods that visualize important features in multi-dimensional and multi-modality medical images by automatically or semi-automatically optimizing the rendering parameters. Our methods enable visualizations necessary for the diagnostic procedure in which 2D slice of interest (SOI) can be augmented with 3D anatomical contextual information to provide accurate spatial localization of 2D features in the SOI; the rendering parameters are automatically computed to guarantee the visibility of 3D features; and changes in 3D features can be tracked in temporal data under the constraint of consistent contextual information. We also present a method for the efficient computation of visibility histograms (VHs) using adaptive binning, which allows our optimal DVR to be automated and visualized in real-time. We evaluated our methods by producing visualizations for a variety of clinically relevant scenarios and imaging data sets. We also examined the computational performance of our methods for these scenarios

Multigranularity Representations for Human Inter-Actions: Pose, Motion and Intention

Tracking people and their body pose in videos is a central problem in computer vision. Standard tracking representations reason about temporal coherence of detected people and body parts. They have difficulty tracking targets under partial occlusions or rare body poses, where detectors often fail, since the number of training examples is often too small to deal with the exponential variability of such configurations. We propose tracking representations that track and segment people and their body pose in videos by exploiting information at multiple detection and segmentation granularities when available, whole body, parts or point trajectories. Detections and motion estimates provide contradictory information in case of false alarm detections or leaking motion affinities. We consolidate contradictory information via graph steering, an algorithm for simultaneous detection and co-clustering in a two-granularity graph of motion trajectories and detections, that corrects motion leakage between correctly detected objects, while being robust to false alarms or spatially inaccurate detections. We first present a motion segmentation framework that exploits long range motion of point trajectories and large spatial support of image regions. We show resulting video segments adapt to targets under partial occlusions and deformations. Second, we augment motion-based representations with object detection for dealing with motion leakage. We demonstrate how to combine dense optical flow trajectory affinities with repulsions from confident detections to reach a global consensus of detection and tracking in crowded scenes. Third, we study human motion and pose estimation. We segment hard to detect, fast moving body limbs from their surrounding clutter and match them against pose exemplars to detect body pose under fast motion. We employ on-the-fly human body kinematics to improve tracking of body joints under wide deformations. We use motion segmentability of body parts for re-ranking a set of body joint candidate trajectories and jointly infer multi-frame body pose and video segmentation. We show empirically that such multi-granularity tracking representation is worthwhile, obtaining significantly more accurate multi-object tracking and detailed body pose estimation in popular datasets

Object detection and tracking using a parts-based approach

One of the main goals of artificial intelligence is to allow computers to understand the world around them. As humans we extract a large amount of knowledge about the world from our visual perception, and the field of computer vision is determined to give computers access to this same wealth of knowledge. One of the fundamental steps in understanding the world is finding specific objects within our field of view, and the related task of following these objects as they move. In this thesis the Implicit Shape Model algorithm, a local feature-based object detection algorithm, is implemented and used to develop an appearance model and object tracking algorithm based on it. This algorithm is very robust to intraclass variation, and can successfully track objects when both occlusion and non-stationary backgrounds are present. The usefulness of the proposed appearance model is analyzed, and results of the algorithm on real video sequences are presented. Several enhancements to the method are also proposed, and performance in terms of recall and precision is analyzed