Molecular gas in NGC6946

We present imaging of molecular gas emission in the star-forming spiral galaxy NGC6946. Our CO(1-0) and CO(3-2) images, made at 22" resolution with the IRAM 30-m and the Heinrich Hertz 10-m radio telescopes, are the most extensive CO observations of this galaxy and are among the most extensive observations of molecular gas in any spiral galaxy. The molecular component in NGC6946 is unusually massive, with a ratio of molecular to atomic Hydrogen of 0.57. A star formation efficiency image for NGC6946 ranges by over two orders of magnitude with highest values found in the northeastern spiral arm, and anticorrelates with the 6cm polarized emission image, which traces the regular part of the magnetic field. We analyse the ISM in NGC6946's disk by making 1-D and 2-D comparisons of images made in several wavebands. A point-by-point correlation technique finds that the molecular gas is closely associated with the 7micron-emitting dust. The high correlation found between the MIR emission and the radio continuum at 6cm cannot be due to dust heating and gas ionization in star-forming regions because the thermal radio emission is less correlated with the MIR than the nonthermal emission. A coupling of magnetic fields to gas clouds is proposed as a possible scenario.Comment: A&A accepted, 23 pages, 11 figures. Version with high resolution figures available at: http://cfa-www.harvard.edu/~wwalsh/sp.htm

Mapping the submillimeter spiral wave in NGC 6946

We have analysed SCUBA 850\mum images of the (near) face-on spiral galaxy NGC 6946, and found a tight correlation between dust thermal emission and molecular gas. The map of visual optical depth relates well to the distribution of neutral gas (HI+H2) and implies a global gas-to-dust ratio of 90. There is no significant radial variation of this ratio: this can be understood, since the gas content is dominated by far by the molecular gas. The latter is estimated through the CO emission tracer, which is itself dependent on metallicity, similarly to dust emission. By comparing the radial profile of our visual optical depth map with that of the SCUBA image, we infer an emissivity (dust absorption coefficient) at 850\mum that is 3 times lower than the value measured by COBE in the Milky Way, and 9 times lower than in NGC 891. A decomposition of the spiral structure half way out along the disk of NGC 6946 suggests an interarm optical depth of between 1 and 2. These surprisingly high values represent 40-80% of the visual opacity that we measure for the arm region (abridged).Comment: 12 pages, 9 figures, accepted in A&

Support Vector Machine classification of strong gravitational lenses

The imminent advent of very large-scale optical sky surveys, such as Euclid and LSST, makes it important to find efficient ways of discovering rare objects such as strong gravitational lens systems, where a background object is multiply gravitationally imaged by a foreground mass. As well as finding the lens systems, it is important to reject false positives due to intrinsic structure in galaxies, and much work is in progress with machine learning algorithms such as neural networks in order to achieve both these aims. We present and discuss a Support Vector Machine (SVM) algorithm which makes use of a Gabor filterbank in order to provide learning criteria for separation of lenses and non-lenses, and demonstrate using blind challenges that under certain circumstances it is a particularly efficient algorithm for rejecting false positives. We compare the SVM engine with a large-scale human examination of 100000 simulated lenses in a challenge dataset, and also apply the SVM method to survey images from the Kilo-Degree Survey.Comment: Accepted by MNRA

The supermassive black hole in the Seyfert 2 galaxy NGC 5252

We present results from HST/STIS long-slit spectroscopy of the gas motions in the nuclear region of the Seyfert 2 galaxy NGC 5252. The observed velocity field is consistent with gas in regular rotation with superposed localized patches of disturbed gas. The dynamics of the circumnuclear gas can be accurately reproduced by adding to the stellar mass component a compact dark mass of MBH = 0.95 (-0.45;+1.45) 10E9 M(sun), very likely a supermassive black hole. Contrarily to results obtained in similar studies rotational broadening is sufficient to reproduce also the behaviour of line widths. The MBH estimated for NGC 5252 is in good agreement with the correlation between MBH and bulge mass. The comparison with the MBH vs sigma relationship is less stringent (mostly due to the relatively large error in sigma); NGC 5252 is located above the best fit line by between 0.3 and 1.2 dex, i.e. 1 - 4 times the dispersion of the correlation. Both the galaxy's and MBH of NGC 5252 are substantially larger than those usually estimated for Seyfert galaxies but, on the other hand, they are typical of radio-quiet quasars. Combining the determined MBH with the hard X-ray luminosity, we estimate that NGC 5252 is emitting at a fraction ~ 0.005 of L(Edd). In this sense, this active nucleus appears to be a quasar relic, now probably accreting at a low rate, rather than a low black hole mass counterpart of a QSO.Comment: Accepted for publication in A&

Thermochemical conversion of waste biomass (cherry rejects) to renewable platform chemicals: FUR and HMF

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Magnetic resonance imaging of brain tissue abnormalities: transverse relaxation time in autism and Tourette syndrome and development of a novel whole-brain myelin mapping technique

The transverse relaxation time (T2) is a fundamental parameter of magnetic resonance imaging sensitive to tissue microstructure and water content, thus offering a non-invasive approach to evaluate abnormalities of brain tissue in-vivo. Prevailing hypotheses of two childhood psychiatric disorders were tested using quantitative T2 imaging and automated region of interest (ROI) analyses. In autism, the under-connectivity theory, which proposes aberrant connectivity within white matter (WM) was assessed, finding T2 to be eleveted in the frontal and parietal lobes, while dividing whole brain data into neurodevelopmentally relevant WM ROIs found increased T2 in bridging and radiate WM. In Tourette syndrome, tissue abnormalities of deep gray matter structures implicated in the symptomology of this disorder were evaluated and increased T2 of the caudate was found. Despite the sensitivity of quantitative T2 measurements to underlying pathophysiology, interpretation remain difficult. However, in WM, the compartmentalization of distinct water environments may lead to the detection of multi-exponential T2 decay. The metric of interest is principally the myelin water fraction (MWF), which is the proportion of the MRI signal arising from water trapped within layers of the myelin sheath. As a proof of concept study, the ability to measure the MWF based on T2* decay was evaluated and compared to a MWF measurements obtained from T2 decay. Data were analysed using both non-negative least squares and a two-pool model. Signal losses near sources of magnetic field inhomogeneity, such as the sinuses, rendered T2* components inseparable, invalidating this approach for whole brain MWF measurements. However, this study demonstrated the suitability of a two-pool model to calculate the MWF in WM. A novel approach, based on the multi-component gradient echo sampling of spin echoes (mcGESSE) and a two-pool model of WM, is proposed and its feasibility demonstrated using simulations. The in-vivo implementation of mcGESSE followed, with reproducibility of MWF measurements being assessed and the potential of an accelerated protocol using parallel imaging being investigated. While further work is needed to assess data quality, this approach shows great potential to obtain whole brain MWF data within a clinically relevant scan time

Assessing Midbrain Abnormalities In Parkinson’s Disease Using Magnetic Resonance Imaging

Diagnosing early-stage Parkinson’s disease (PD) and its manifestations is still a clinical challenge. Previous imaging studies using iron, neuromelanin (NM) and the Nigrosome-1 (N1) measures in the substantia nigra (SN) by themselves have been unable to provide sufficiently high diagnostic performance for these methods to be adopted clinically. In this dissertation, we start by studying idiopathic PD patients at their intermediate stages of the disease to evaluate the role of global and regional iron in the major deep gray matter nuclei. Then, we only focus on the NM complex in the midbrain and how neuronal loss interact with iron overload as well as their relationship with clinical scores strictly on early PD patients. Finally, by taking one more step back in the disease progression process, we investigate the impact of iron deposition and N1 appearance in idiopathic rapid eye movement sleep behavior disorder (RBD) as the prodromal stage of PD. The results of this work are summarized as the following: 1) the increase in iron in the SN in some PD patients is higher than the normal range in healthy controls (HC) as found in both regional and global analyses and that regional high iron content may provide a means to separate two populations of PD patients; one with and one without iron increases in the SN; 2) we have introduced a rapid five-minute 3D approach to depict NM degeneration and iron deposition simultaneously which provides a practical MR imaging method to differentiate early stage subjects with PD from HCs with an approximately 98% accuracy; and finally 3) iRBD patients were found to have a higher incidence of N1 loss, reduced volume and elevated iron levels in a few brain structures as well as cognitive and motor impairment scores being correlated with iron deposition of several cerebral nuclei. All these in vivo biomarkers put together can significantly contribute to a better understanding of the underlying pathophysiology in PD onset and progression with the ultimate goal being a more confident clinical diagnosis prior to symptomatic dysfunction