3,701 research outputs found

    Nonspecific Networking

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    A new model of strategic network formation is developed and analyzed, where an agent's investment in links is nonspecific. The model comprises a large class of games which are both potential and super- or submodular games. We obtain comparative statics results for Nash equilibria with respect to investment costs for supermodular as well as submodular networking games. We also study logit-perturbed best-response dynamics for supermodular games with potentials. We find that the associated set of stochastically stable states forms a sublattice of the lattice of Nash equilibria and derive comparative statics results for the smallest and the largest stochastically stable state. Finally, we provide a broad spectrum of applications from social interaction to industrial organization. Models of strategic network formation typically assume that each agent selects his direct links to other agents in which to invest. Nonspecific networking means that an agent cannot select a specific subset of feasible links which he wants to establish or strengthen. Rather, each agent chooses an effort level or intensity of networking. In the simplest case, the agent faces a binary choice: to network or not to network. If an agent increases his networking effort, all direct links to other agents are strengthened to various degrees. We assume that benefits accrue only from direct links. The set of agents or players is finite. Each agent has a finite strategy set consisting of the networking levels to choose from. For any pair of agents, their networking levels determine the individual benefits which they obtain from interacting with each other. An agent derives an aggregate benefit from the pairwise interactions with all others. In addition, the agent incurs networking costs, which are a function of the agent's own networking level. The agent's payoff is his aggregate benefit minus his cost.Network Formation, Potential Games, Supermodular Games

    On The Table 2014 Impact Report

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    In every Chicago neighborhood and many suburban communities, thousands of residents came together to break bread and discuss how to collaboratively build and maintain strong, safe and dynamic communities. This report summarizes conversations based on a wide variety of data collected by or made available to the Institute for Policy and Civic Engagement (IPCE) and addresses three major questions IPCE posed to understand the impact of the initiative: who participated, what was discussed, and how were participants impacted by the conversations? These conversations were intended to provide a platform for partnering with and inspiring participants, organizations, and institutions in the region to take action to improve quality of life and to build a more sustainable future for the Chicago region

    Aquaculture Asia, vol. 8, no. 4, pp.1-52, October - December 2003

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    CONTENTS: Freshwater prawn, Macrobrachium nobilii a promising candidate for rural nutrition, by Pitchimuthu Mariappan, P. Balamurugan, and Chellam Balasundaram. Snapshots of a clean, innovative, socially responsible fishfarm in Sri Lanka, by Pedro Bueno. Introduction of rainbow trout Onchorynchus mykiss in Nepal: Constraints and prospects, by Tek Bahadur Gurung, Sadhu Ram Basnet. Tilapia seed production in Ho Chi Minh City, Southern Vietnam, by H. P. V. Huy, A. MacNiven, N. V. Tu, Ram C. Bhujel and David C. Little. Seaweed Mariculture: Scope And Potential In India, by Sajid I. Khan and S. B. Satam. Growth enhancement of carp and prawn through dietary sodium chloride supplementation, by P.Keshavanath, B. Gangadhara and Savitha Khadri. Fertilization, soil and water quality management in small-scale ponds, by S. Adhikari Shrimp harvesting technology on the south west coast of Bangladesh, by S. M. Nazmul Alam, Michael J. Phillips and C. K. Lin. The “Gher Revolution”, by M.C. Nandeesha [Farmers as Scientists series] Aquaculture Compendium – case study component, by Peter Edwards. Rice-Fish Culture in China, by Fang Xiuzhen. Exercising responsibilities to tackle aquatic animal diseases, by CV Mohan. Application of immunostimulants in larviculture: Feasibility and challenges, by ZhouJin. Marine Finfish Sectio

    Communication networks with endogenous link strength

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    This paper analyzes the formation of networks when players choose how much to invest in each relationship. We suppose that players have a fixed endowment that they can allocate across links, and in the baseline model, suppose that link strength is an additively separable and convex function of individual investments, and that agents use the path which maximizes the product of link strengths. We show that both the stable and efficient network architectures are stars. However, the investments of the hub may differ in stable and efficient networks. Under alternative assumptions on the investment technology and the reliability measure, other network architectures can emerge as efficient and stable

    Combating stem and leaf rust of wheat: Historical perspective, impacts, and lessons learned

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    millions fed, food security, wheat rust, stem rust, leaf rust, Norman Borlaug,

    Interaction on hypergraphs

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    Interaction on hypergraphs generalizes interaction on graphs, also known as pairwise local interaction. For games played on a hypergraph which are supermodular potential games, logit-perturbed best-response dynamics are studied. We find that the associated stochastically stable states form a sublattice of the lattice of Nash equilibria and derive comparative statics results for the smallest and the largest stochastically stable state. In the special case of networking games, we obtain comparative statics results with respect to investment costs, for Nash equilibria of supermodular games as well as for Nash equilibria of submodular games

    Diagnosis and outcome of oesophageal Crohn's disease

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    BACKGROUND AND AIMS: Crohn's disease (CD) can involve any part of the gastrointestinal tract. We aimed to characterize clinical, endoscopic, histologic features and treatment outcomes of CD patients with oesophageal involvement. METHODS: We collected cases through a retrospective multicentre European Crohn's and Colitis Organisation CONFER [COllaborative Network For Exceptionally Rare case reports] project. Clinical data were recorded in a standardized case report form. RESULTS: A total of 40 patients were reported [22 males, mean (±SD, range) age at oesophageal CD diagnosis: 25 (±13.3, 10-71) years and mean time of follow-up: 67 (±68.1, 3-240) months]. Oesophageal involvement was established at CD diagnosis in 26 patients (65%) and during follow-up in 14. CD was exclusively located in the oesophagus in 2 patients. Thirteen patients (32.2%) were asymptomatic at oesophageal disease diagnosis. Oesophageal strictures were present in 5 patients and fistulizing oesophageal disease in one. Eight patients exhibited granulomas on biopsies. Proton-pump inhibitors (PPIs) were administered in 37 patients (92.5%). Three patients underwent endoscopic dilation for symptomatic strictures and none oesophageal-related surgery. Diagnosis in pre-established CD resulted in treatment modifications in 9/14 patients. Clinical remission of oesophageal disease was seen in 33/40 patients (82.5%) after a mean time of 7 (±5.6, 1-18) months. Follow-up endoscopy was performed in 29/40 patients and 26/29 (89.7%) achieved mucosal healing. CONCLUSION: In this case series the endoscopic and histologic characteristics of isolated oesophageal CD were similar to those reported in other sites of involvement. Treatment was primarily conservative, with PPIs administered in the majority of patients and modifications in pre-existing IBD-related therapy occurring in two thirds of them. Clinical and endoscopic remission was achieved in more than 80% of the patients.info:eu-repo/semantics/publishedVersio

    Redox signaling, Nox5 and vascular remodeling in hypertension

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    Purpose of review: Extensive data indicate a role for reactive oxygen species (ROS) and redox signaling in vascular damage in hypertension. However, molecular mechanisms underlying these processes remain unclear, but oxidative post-translational modification of vascular proteins is critical. This review discusses how proteins are oxidatively modified and how redox signaling influences vascular smooth muscle cell growth and vascular remodeling in hypertension. We also highlight Nox5 as a novel vascular ROS-generating oxidase. Recent findings: Oxidative stress in hypertension leads to oxidative imbalance that affects vascular cell function through redox signaling. Many Nox isoforms produce ROS in the vascular wall, and recent findings show that Nox5 may be important in humans. ROS regulate signaling by numerous processes including cysteine oxidative post-translational modification such as S-nitrosylation, S-glutathionylation and sulfydration. In vascular smooth muscle cells, this influences cellular responses to oxidative stimuli promoting changes from a contractile to a proliferative phenotype. Summary: In hypertension, Nox-induced ROS production is increased, leading to perturbed redox signaling through oxidative modifications of vascular proteins. This influences mitogenic signaling and cell cycle regulation, leading to altered cell growth and vascular remodeling in hypertension

    Are REST APIs for Cloud Computing Well-Designed? An Exploratory Study

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    International audienceCloud computing is currently the most popular model to offer and access computational resources and services. Many cloud providers use the REST architectural style (Representational State Transfer) for offering such computational resources. However, these cloud providers face challenges when designing and exposing REST APIs that are easy to handle by end-users and/or developers. Yet, they benefit from best practices to help them design understandable and reusable REST APIs. However, these best practices are scattered in the literature and they have not be studied systematically on real-world APIs. Consequently, we propose two contributions. In our first contribution, we survey the literature and compile a catalog of 73 best practices in the design of REST APIs making APIs more understandable and reusable. In our secondcontribution, we perform a study of three different and well-known REST APIs from three cloud providers to investigate how their APIs are offered and accessed. These cloud providers are Google Cloud Platform, OpenStack, and Open Cloud Computing Interface (OCCI). In particular, we evaluate the coverage of the features provided by the REST APIsof these cloud providers and their conformance with the best practices for REST APIs design. Our results show that Google Cloud follows 66% (48/73), OpenStack follows 62% (45/73), and OCCI 1.2 follows 56% (41/73) of the best practices. Second, although these numbers are not necessarily high, partly because of the strict and precise specification of best practices, we showed that cloud APIs reach an acceptable level of maturity

    Media consumption and creation in attitudes toward and knowledge of inflammatory bowel disease: web-based survey

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    BACKGROUND: Inflammatory bowel disease (IBD) is a chronic gastrointestinal condition affecting over 5 million people globally and 1.6 million in the United States but currently lacks a precisely determined cause or cure. The range of symptoms IBD patients experience are often debilitating, and the societal stigmas associated with some such symptoms can further degrade their quality of life. Better understanding the nature of this public reproach then is a critical component for improving awareness campaigns and, ultimately, the experiences of IBD patients. OBJECTIVE: The objective of this study was to explore and assess the public's awareness and knowledge of IBD, as well as what relationship, if any, exists between the social stigma surrounding IBD, knowledge of the disease, and various media usage, including social media. METHODS: Utilizing a Web-based opt-in platform, we surveyed a nationally representative sample (n=1200) with demographics mirroring those of the US Census figures across baseline parameters. Using constructed indices based on factor analysis, we were able to build reliable measures of personal characteristics, media behaviors, and perceptions and knowledge of IBD. RESULTS: Among the American public, IBD is the most stigmatized of seven diseases, including genital herpes and human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS). Additionally, IBD knowledge is generally low with 11.08% (133/1200) of the sample indicating no familiarity with the disease and 85.50% (1026/1200) of participants inaccurately answering two-thirds of the IBD index questions with which their knowledge was assessed. Increased knowledge of IBD is associated with lower levels of stigma. However, social media use is currently related to lower levels of IBD knowledge (P<.05). Furthermore, findings indicate that participants who most frequently engaged in producing social media content are less knowledgeable about IBD (P<.10), highlighting the potential for a dangerous cycle should they be contributing to a Web-based IBD dialogue. CONCLUSIONS: Greater efforts must be taken to stymie IBD misinformation across all media, but especially in social media channels, to increase IBD knowledge and reduce stigma surrounding IBD. These findings pave the way for further research qualitatively examining the pervasiveness of specific IBD messages found in today's social media landscape and their impact on enacted stigmas so as to better equip providers and patient advocacy organizations with impactful communication solutions
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