Hematocolpos as a Result of Delayed Treatment of Acute Straddle Injury in an Adolescent Girl

Accidental genital trauma is most commonly caused by straddle-type injuries and is usually treatable by nonoperative management, and most of the injuries have a good prognosis. When the bleeding occurred due to straddle injury in adolescent girl, experienced gynecological examination and treatment were very important. We experienced a case of straddle injury to the posterior fourchette that caused acute hematocolpos due to delayed adequate treatment with hypotension and acute abdomen in an adolescent girl. This case shows the importance of careful and accurate physical and gynecological examination and adequate and prompt treatment of genital trauma in adolescent girls

Peripartum Hysterectomy

Peripartum hysterectomy is uncommon in modern obstetrics. It is mostly performed as an emergency procedure to control life-threatening haemorrhage. Despite recent technical advances in medicine, it is associated with high rates of morbidity and mortality. Peripartum hysterectomy constitutes a life-saving procedure

Genital trauma due to coital injury in women at Pikine National Hospital: epidemiological, diagnostic, and therapeutic insights from 32 cases

Background: Sexual trauma involves very different situations in women, most of which are uncommon in clinical practice. These are, often minor lesions following “normal” sexual act, not requiring medical attention. In general, it is estimated at less than 1% of gynecological emergencies. Methods: This is a retrospective, descriptive and analytical study which extends over a period from March 2019 to January 2023, i.e., a duration of 3 years and 10 months. Results: During the study period, 32 cases of per coital trauma were collected out of a total of 18,924 gynecological and obstetrical emergencies, i.e., a frequency of 0.16%. The 20–40-year-old age group was the most represented with a rate of 72.7% and most of them were married (72.7%). The trauma occurred during consensual sexual intercourse with a male, rate of 75.8% compared to 24.2% of non-consensual reports. It was the first sexual act in 69.7% of cases and mainly occurred at night (72.7%). Patients mainly consulted for vaginal bleeding. The relationship between the type of lesion and parity as well as that between the type of lesion and the circumstances of occurrence showed that complex lesions were more frequently encountered in nulliparous women during consensual sexual act. Conclusions: Percoital genital trauma in women remains an under-reported condition despite the enormous risks to the vital, but also functional and psychological prognosis

Surgical operations in short-stay hospitals for discharged patients, United States--1965

[by Edythe A. Gray and Sue Meads]Also available via the World Wide Web.Bibliography: p. 8

The nature and frequency of genital injuries sustained by female rape victims in Johannesburg

A research report submitted to the Faculty of Health Sciences, University of the Witwatersrand, in partial fulfilment of the requirements for the degree of Master of Science in Emergency Medicine. MScMed (Emergency Medicine) Johannesburg, November 2013Background: Little research has addressed the types and meaning of genital injury in South African rape victims. In South Africa, rape victims in private practice are examined using gross visualisation and a light source only. Research has shown that the use of toluidine blue and/ or a colposcope increases the number of injuries seen. Objective: To determine rape victim demographics and describe the genital injuries and other associated injuries reported during medico-legal examination of female rape victims older than 15 in four private Johannesburg hospitals between 1 January 2008 and 31 December 2009, as well as to determine any associations between these variables and the race or age of the victim. Method: A retrospective chart review of 310 sexual assault victims seen at these hospitals. Results: Black victims made up 62% of the study. One genital injury was recorded for 27% of the victims, while 21% had between 2 and 8 of a possible 11 injuries. The most commonly injured sites were the posterior fourchette, the hymen and the fossa navicularis. Bruising was the most common associated injury. Alcohol was reported in just fewer than 10% of cases. Conclusion: The incidence of positive genital injury documented is comparable to other research. Genital injuries are not inevitable consequences of sexual assault

Massive Postpartum Hemorrhage: Protocol and Red Code

Postpartum hemorrhage (PPH) is the leading cause of maternal death. In developing countries, approximately 8% of maternal death is caused by PPH. Protocols should provide a standardized approach to evaluate and monitor the patients. A standard protocol must be recognized by the institution and must be accepted and known by all team members. Additionally, it is important to have a massive obstetric hemorrhage protocol (red code) for those patients with an important bleeding who require blood products available as soon as possible. In the red code activation protocol there are several key points to consider: the management algorithm must be known and accepted by all team members, a clear and effective communication between the team must be established and all the participants must know the role they play. Massive obstetric hemorrhage has a multidisciplinary implication: obstetricians, anesthesiologists, pediatricians, midwife, nurses, auxiliary staff, and laboratory blood bank staff. The active participation of the multidisciplinary team in simulations before the protocols implementation facilitates the evaluation of critical points and subsequent changes before their final application, the assessment of the adequacy of circuits and infrastructure, as well as a better protocols compliance

Estudo de polimorfismo de DNA do gene codificador da LOXL-1 e prolapso de órgãos pélvicos em mulheres brasileiras

Introduction and hypothesis: We verified the presence of single nucleotide polymorphisms (SNP) rs2165241 of the lysyl oxidase-like 1 (LOXL-1) gene and the association with pelvic organ prolapse (POP) in Brazilian women and determined risk factors for POP development. Methods: We assessed 630 postmenopausal women divided into POP (stages III and IV) and control (stages 0 and I) groups by examination and peripheral blood sample collection. DNA sequence of interest was analyzed by real-time reverse-transcriptase polymerase chain reaction (RT-PCR). We used logistic regression models for the analysis, with p < 0.05 for significance. Results: There were no association between the polymorphism analyzed and POP. Multiple logistic regression analysis identified age [odds ratio (OR) = 1.09, confidence interval (CI) 95%= 1.07; 1.12], number of vaginal births (OR = 2.17, CI 95%= 1.67; 2.82), and family history (OR = 2.27, CI 95%= 1.41; 3.66) as independent risk factors for POP. Cesarean section was shown to be a protective factor (OR = 0.73, CI 95%= 0.56; 0.95). Conclusion: Our research suggests that there is a lack of association between DNA polymorphism rs2165241 of LOXL-1 with advanced POP in this population.Introdução e hipótese: Verificamos a presença do polimorfismo de nucleotídeo único (SNP) rs2165241 do gene lysyl oxidase-1 (LOXL-1) e a associação com prolapso de órgãos pélvicos (POP) em mulheres brasileiras e determinamos os fatores de risco para o desenvolvimento de POP. Métodos: Avaliamos 630 mulheres na pós-menopausa divididas nos grupos POP (estágios III e IV) e controle (estágios 0 e I) através de exame físico e coleta de amostra de sangue periférico. A sequência de DNA de interesse foi analisada por reação em cadeia da polimerase via transcriptase reversa em tempo real (RT-PCR). Utilizamos modelos de regressão logística para a análise, com p<0,05 para significância. Resultados: Não houve associação entre o polimorfismo analisado e o POP. Análise de regressão logística múltipla identificou idade [odds ratio (OR) = 1,09, intervalo de confiança (IC) 95% = 1,07; 1,12], número de partos vaginais (OR = 2,17, IC 95% = 1,67; 2,82) e histórico familiar (OR = 2,27, IC 95% = 1,41; 3,66) como fatores de risco independentes para POP. A cesárea mostrou-se um fator de proteção (OR = 0,73, IC 95% = 0,56; 0,95). Conclusão: Nosso estudo sugere a falta de associação entre polimorfismo rs2165241 da LOXL-1 e POP avançado nesta população.Dados abertos - Sucupira - Teses e dissertações (2019

Estudo de polimorfismo de DNA do gene codificador da LOXL-1 e prolapso de órgãos pélvicos em mulheres brasileiras

Introduction and hypothesis: We verified the presence of single nucleotide polymorphisms (SNP) rs2165241 of the lysyl oxidase-like 1 (LOXL-1) gene and the association with pelvic organ prolapse (POP) in Brazilian women and determined risk factors for POP development. Methods: We assessed 630 postmenopausal women divided into POP (stages III and IV) and control (stages 0 and I) groups by examination and peripheral blood sample collection. DNA sequence of interest was analyzed by real-time reverse-transcriptase polymerase chain reaction (RT-PCR). We used logistic regression models for the analysis, with p < 0.05 for significance. Results: There were no association between the polymorphism analyzed and POP. Multiple logistic regression analysis identified age [odds ratio (OR) = 1.09, confidence interval (CI) 95%= 1.07; 1.12], number of vaginal births (OR = 2.17, CI 95%= 1.67; 2.82), and family history (OR = 2.27, CI 95%= 1.41; 3.66) as independent risk factors for POP. Cesarean section was shown to be a protective factor (OR = 0.73, CI 95%= 0.56; 0.95). Conclusion: Our research suggests that there is a lack of association between DNA polymorphism rs2165241 of LOXL-1 with advanced POP in this population.Introdução e hipótese: Verificamos a presença do polimorfismo de nucleotídeo único (SNP) rs2165241 do gene lysyl oxidase-1 (LOXL-1) e a associação com prolapso de órgãos pélvicos (POP) em mulheres brasileiras e determinamos os fatores de risco para o desenvolvimento de POP. Métodos: Avaliamos 630 mulheres na pós-menopausa divididas nos grupos POP (estágios III e IV) e controle (estágios 0 e I) através de exame físico e coleta de amostra de sangue periférico. A sequência de DNA de interesse foi analisada por reação em cadeia da polimerase via transcriptase reversa em tempo real (RT-PCR). Utilizamos modelos de regressão logística para a análise, com p<0,05 para significância. Resultados: Não houve associação entre o polimorfismo analisado e o POP. Análise de regressão logística múltipla identificou idade [odds ratio (OR) = 1,09, intervalo de confiança (IC) 95% = 1,07; 1,12], número de partos vaginais (OR = 2,17, IC 95% = 1,67; 2,82) e histórico familiar (OR = 2,27, IC 95% = 1,41; 3,66) como fatores de risco independentes para POP. A cesárea mostrou-se um fator de proteção (OR = 0,73, IC 95% = 0,56; 0,95). Conclusão: Nosso estudo sugere a falta de associação entre polimorfismo rs2165241 da LOXL-1 e POP avançado nesta população.Dados abertos - Sucupira - Teses e dissertações (2019