31,511 research outputs found
A multi-view approach to cDNA micro-array analysis
The official published version can be obtained from the link below.Microarray has emerged as a powerful technology that enables biologists to study thousands of genes simultaneously, therefore, to obtain a better understanding of the gene interaction and regulation mechanisms. This paper is concerned with improving the processes involved in the analysis of microarray image data. The main focus is to clarify an image's feature space in an unsupervised manner. In this paper, the Image Transformation Engine (ITE), combined with different filters, is investigated. The proposed methods are applied to a set of real-world cDNA images. The MatCNN toolbox is used during the segmentation process. Quantitative comparisons between different filters are carried out. It is shown that the CLD filter is the best one to be applied with the ITE.This work was supported in part by the Engineering and Physical Sciences Research
Council (EPSRC) of the UK under Grant GR/S27658/01, the National Science Foundation of China under Innovative Grant 70621001, Chinese Academy of Sciences
under Innovative Group Overseas Partnership Grant, the BHP Billiton Cooperation of Australia Grant, the International Science and Technology Cooperation Project of China
under Grant 2009DFA32050 and the Alexander von Humboldt Foundation of Germany
Hyperspectral Unmixing Overview: Geometrical, Statistical, and Sparse Regression-Based Approaches
Imaging spectrometers measure electromagnetic energy scattered in their
instantaneous field view in hundreds or thousands of spectral channels with
higher spectral resolution than multispectral cameras. Imaging spectrometers
are therefore often referred to as hyperspectral cameras (HSCs). Higher
spectral resolution enables material identification via spectroscopic analysis,
which facilitates countless applications that require identifying materials in
scenarios unsuitable for classical spectroscopic analysis. Due to low spatial
resolution of HSCs, microscopic material mixing, and multiple scattering,
spectra measured by HSCs are mixtures of spectra of materials in a scene. Thus,
accurate estimation requires unmixing. Pixels are assumed to be mixtures of a
few materials, called endmembers. Unmixing involves estimating all or some of:
the number of endmembers, their spectral signatures, and their abundances at
each pixel. Unmixing is a challenging, ill-posed inverse problem because of
model inaccuracies, observation noise, environmental conditions, endmember
variability, and data set size. Researchers have devised and investigated many
models searching for robust, stable, tractable, and accurate unmixing
algorithms. This paper presents an overview of unmixing methods from the time
of Keshava and Mustard's unmixing tutorial [1] to the present. Mixing models
are first discussed. Signal-subspace, geometrical, statistical, sparsity-based,
and spatial-contextual unmixing algorithms are described. Mathematical problems
and potential solutions are described. Algorithm characteristics are
illustrated experimentally.Comment: This work has been accepted for publication in IEEE Journal of
Selected Topics in Applied Earth Observations and Remote Sensin
Data-driven Soft Sensors in the Process Industry
In the last two decades Soft Sensors established themselves as a valuable alternative to the traditional means for the acquisition of critical process variables, process monitoring and other tasks which are related to process control. This paper discusses characteristics of the process industry data which are critical for the development of data-driven Soft Sensors. These characteristics are common to a large number of process industry fields, like the chemical industry, bioprocess industry, steel industry, etc. The focus of this work is put on the data-driven Soft Sensors because of their growing popularity, already demonstrated usefulness and huge, though yet not completely realised, potential. A comprehensive selection of case studies covering the three most important Soft Sensor application fields, a general introduction to the most popular Soft Sensor modelling techniques as well as a discussion of some open issues in the Soft Sensor development and maintenance and their possible solutions are the main contributions of this work
The Multiscale Morphology Filter: Identifying and Extracting Spatial Patterns in the Galaxy Distribution
We present here a new method, MMF, for automatically segmenting cosmic
structure into its basic components: clusters, filaments, and walls.
Importantly, the segmentation is scale independent, so all structures are
identified without prejudice as to their size or shape. The method is ideally
suited for extracting catalogues of clusters, walls, and filaments from samples
of galaxies in redshift surveys or from particles in cosmological N-body
simulations: it makes no prior assumptions about the scale or shape of the
structures.}Comment: Replacement with higher resolution figures. 28 pages, 17 figures. For
Full Resolution Version see:
http://www.astro.rug.nl/~weygaert/tim1publication/miguelmmf.pd
Generalized Perceptual Linear Prediction (gPLP) Features for Animal Vocalization Analysis
A new feature extraction model, generalized perceptual linear prediction (gPLP), is developed to calculate a set of perceptually relevant features for digital signal analysis of animalvocalizations. The gPLP model is a generalized adaptation of the perceptual linear prediction model, popular in human speech processing, which incorporates perceptual information such as frequency warping and equal loudness normalization into the feature extraction process. Since such perceptual information is available for a number of animal species, this new approach integrates that information into a generalized model to extract perceptually relevant features for a particular species. To illustrate, qualitative and quantitative comparisons are made between the species-specific model, generalized perceptual linear prediction (gPLP), and the original PLP model using a set of vocalizations collected from captive African elephants (Loxodonta africana) and wild beluga whales (Delphinapterus leucas). The models that incorporate perceptional information outperform the original human-based models in both visualization and classification tasks
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