Dental drill noise reduction using a combination of active noise control, passive noise control and adaptive filtering

Dental drills produce a characteristic high frequency, narrow band noise that is uncomfortable for patients and is also known to be harmful to dentists under prolonged exposure. It is therefore desirable to protect the patient and dentist whilst allowing two-way communication. A solution is to use a combination of the three main noise control methods, namely, Passive Noise Control (PNC), Adaptive Filtering (AF) and Active Noise Control (ANC). This paper discusses the application of the three methods to reduce dental drill noise while allowing two-way communication. Experimental setup for measuring the noise reduction by PNC is explained and results from different headphones and headphone types are presented. The implementation and results of an AF system using the Least Mean Square (LMS) algorithm are shown. ANC requires a modification of the LMS algorithm due to the introduction of the electro-acoustical cancellation path transfer function to compensate for the delays introduced by the control system. Therefore a cancellation path transfer function modeling method based on the filtered reference LMS (FXLMS) algorithm is presented along with preliminary results of the implementation

Genetic noise control via protein oligomerization

Gene expression in a cell entails random reaction events occurring over disparate time scales. Thus, molecular noise that often results in phenotypic and population-dynamic consequences sets a fundamental limit to biochemical signaling. While there have been numerous studies correlating the architecture of cellular reaction networks with noise tolerance, only a limited effort has been made to understand the dynamic role of protein-protein interactions. Here we have developed a fully stochastic model for the positive feedback control of a single gene, as well as a pair of genes (toggle switch), integrating quantitative results from previous in vivo and in vitro studies. We find that the overall noise-level is reduced and the frequency content of the noise is dramatically shifted to the physiologically irrelevant high-frequency regime in the presence of protein dimerization. This is independent of the choice of monomer or dimer as transcription factor and persists throughout the multiple model topologies considered. For the toggle switch, we additionally find that the presence of a protein dimer, either homodimer or heterodimer, may significantly reduce its random switching rate. Hence, the dimer promotes the robust function of bistable switches by preventing the uninduced (induced) state from randomly being induced (uninduced). The specific binding between regulatory proteins provides a buffer that may prevent the propagation of fluctuations in genetic activity. The capacity of the buffer is a non-monotonic function of association-dissociation rates. Since the protein oligomerization per se does not require extra protein components to be expressed, it provides a basis for the rapid control of intrinsic or extrinsic noise

Active noise control for high frequencies

There are many applications that can benefit from Active Noise Control (ANC) such as in aircraft cabins and air conditioning ducts, i.e. in situations where technology interferes with human hearing in a harmful way or disrupts communication. Headsets with analogue ANC circuits have been used in the armed forces for attenuating frequencies below 1 kHz, which when combined with passive filtering offers protection across the whole frequency range of human hearing. A dental surgery is also a noisy environment; in which dental drill noise is commonly off-putting for many patients and is believed to harm the dentist’s hearing over a long period of time. However, dealing with dental drill noise is a different proposition from the applications mentioned above as the frequency range of the peak amplitudes goes from approximately 1.5 kHz to 12 kHz, whereas conventional ANC applications consider a maximum of 1.5 kHz. This paper will review the application of ANC at low frequencies and justify an approach for dealing with dental noise using digital technologies at higher frequencies. The limits of current ANC technologies will be highlighted and the means of improving performance for this dental application will be explored. In particular, technicalities of implementing filtering algorithms on a Digital Signal Processor will be addressed

Shot-noise-limited control-loop noise in an interferometer with multiple degrees of freedom

Precise measurements, such as those made with interferometric gravitational-wave detectors, require the measurement device to be properly controlled so that the sensitivity can be as high as possible. Mirrors in the interferometer are to be located at specific operation points to isolate laser noise and to accumulate the signal in resonant cavities. On the other hand, rigid control of an auxiliary degree of freedom may result in imposing sensing noise of the control on the target object as excess force noise. Evaluation of this so-called loop noise is important in order to design a decent control scheme of the measurement device. In this paper, we show the method to calculate the level of loop noise, which has been recently implemented in simulation tools that are broadly used for designing gravitational-wave detectors